Los Angeles Angels vs Milwaukee Brewers Prediction 9/18/2025 Today’s MLB Picks

In this article, we will formulate an Angels vs Brewers Prediction for this MLB game on Thursday, September 18th at the American Family Field in the third game of this series, with the Brewers having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 93-59 record this season and are sitting on the first place of the NL Central. They have a 50-27 home record and are 74-73 in over/under. They are coming off a 9-2 home victory over the Angels, and are 4-1 in their last 5 games. Over is 7-2 in their last 9 games and are playing the Cardinals and the Padres next.

The Brewers have a .261 batting average this season, .334 OBP and .409 Slugging percentage. Milwaukee’s pitching staff has a 3.61 ERA and 1.22 WHIP. Brice Turang leads the Brewers with 158 hits, while Christian Yelich leads the team in RBI, with 99, adding a team-high 29 home runs. Sal Frelick is the team’s best hitter with a .296 batting average.

Quinn Priester (R) is the projected starting pitcher for the Brewers, and he has a 13-2 record, 3.25 ERA and 1.23 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 69-83 record this season and are sitting on the 4th place of the AL West. The Angels have a 32-45 road record and 84-65 in over/under They are coming off a 2-9 road defeat by the Brewers, and have six consecutive losses. Over is 9-3 in their last 12 games and are playing the Rockies and the Royals next.

The Angels have a .226 batting average this season, .300 OBP and .398 Slugging percentage. LA’s pitching staff has a 4.89 ERA and 1.44 WHIP. Zach Neto leads the Angels with 129 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 100 RBI, while Jo Adell adds a team-high 36 home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 6-11 record, 4.08 ERA and 1.46 WHIP.

Los Angeles Angels @ Milwaukee Brewers Betting Trends: September 18, 2025

• Probable Starting Pitcher: Quinn Priester      Record this season: 13-2      ERA: 3.25
• Home Record: 7-1
• Last 5 against Angels: 0-1

Why the Milwaukee Brewers will win

• The home team has won each of the Angels’ last eight games.
• The Angels have lost each of their last seven road games.
• The Angels have failed to cover the run line in each of their last eight night games against NL Central opponents following a loss.
• The Brewers have covered the run line in eight of their last nine night games against AL West opponents that held a losing record.
• The Angels have lost the first inning in three of their last four games.
• The Brewers have led after 3 innings in each of their last seven games as home favorites against AL West opponents.
• The Angels have trailed after 5 innings in each of their last eight games as underdogs against National League opponents.

• Probable Starting Pitcher: Yusei Kikuchi      Record this season: 6-11      ERA: 4.08
• Road Record: 1-8
• Last 5 against Brewers: 2-1

Why the Los Angeles Angels will win

• The Brewers have lost five of their last seven games as home favorites after playing the previous day.
• The Angels have won 12 of their last 18 games as road underdogs against National League opponents following a loss.
• The Brewers have failed to cover the run line in seven of their last eight home games following a win.

Total Runs Facts

• Seven of the Angels’ last eight night games after playing the previous day have gone OVER the total runs line.
• Each of the Brewers’ last four games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Brewers’ last 11 night games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Angels’ last 11 games as underdogs against National League opponents.

Milwaukee Brewers Player Prop Facts

• Andrew Vaughn has hit a home run in two of his last three appearances with his team as a home favorite against AL opponents.
• Andrew Vaughn has recorded at least one Double in each of his last three appearances with his team as a favorite against the Angels.
• Sal Frelick has recorded at least one hit in each of his last 12 appearances with the Brewers as home favorites against AL opponents.
• Quinn Priester ranks T9th in the league for Wins (13) this season.

Los Angeles Angels Player Prop Facts

• Yusei Kikuchi has recorded five or more strikeouts in 12 of his last 13 road appearances against NL opponents.
• Travis d’Arnaud has hit at least one home run in each of his last two road appearances against the Brewers.
• Zach Neto has recorded at least one hit in each of his last 10 Thursday night appearances.
• Jo Adell ranks 8th in the league in Home Runs (36) this season.

Matchup/League Facts

• The Brewers rank 2nd in the league for batting average this season (.261).
• The Brewers rank 2nd in the league for on-base percentage this season (.334).
• The Angels rank 30th in the league for doubles this season (202).
• The Angels rank 30th in the league for strikeouts against this season (1510).

Angels vs Brewers Prediction

The Brewers are 6-2 in their last 8 meetings against the Angels, and are 4-2 in their last 6 meetings Milwaukee. Under is 5-3-1 in their last 9 meetings.

In this Angels vs Brewers Prediction, the Brewers are coming as -185 home favorites. The Brewers are dominating the Angels in this series, having won both games with a combined 18-4 score. They are putting Priester on the mound, who has a stellar 11-2 record, and has been in good form lately, with a 2.25 ERA across his last 5 starts. On the flip side, Kikuchi has been terrible on the road for the Angels, with a 5.16 road ERA, and struggling mightily lately, with a 1-4 record and 7.30 ERA in his last 5 starts. Milwaukee has the third-best offense in baseball, and the Angels the third-worst bullpen ERA. I expect another dominating win by the hosts, so take the Milwaukee Brewers on the moneyline in this one.