Los Angeles Angels vs Colorado Rockies Prediction 9/21/2025 Today’s MLB Picks

The Los Angeles Angels and Colorado Rockies meet Sunday in MLB action at Coors Field. Here’s a Los Angeles Angels vs Colorado Rockies Prediction. This article will include a Los Angeles Angels vs Colorado Rockies Pick.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 70-85 on the year and play the Royals and Astros next. The Los Angeles Angels are batting .226 on the season, have a .299 OBP, and a .399 slugging percentage. The Los Angeles Angels pitching staff has a 4.87 ERA and a 1.41 WHIP. Zach Neto leads the Los Angeles Angels with 129 hits and 62 RBI, while Taylor Ward and Nolan Schanuel have combined for 254 hits and 153 RBI.

Caden Dana gets the ball for the Los Angeles Angels, and he is 0-2 with a 7.45 ERA and 23 strikeouts this season. This will be Dana’s first career game against the Colorado Rockies.

Colorado Rockies Betting Preview

The Colorado Rockies are 42-113 on the year and play the Mariners and Giants next. The Colorado Rockies are batting .239 on the season, have a .295 OBP, and a .389 slugging percentage. The Colorado Rockies pitching staff has a 6.02 ERA and a 1.59 WHIP. Hunter Goodman leads the Colorado Rockies with 144 hits and 88 RBI while Jordan Beck and Mickey Moniak have combined for 251 hits and 120 RBI.

Kyle Freeland gets the ball for the Colorado Rockies, and he is 4-16 with a 5.14 ERA and 113 strikeouts this season. Freeland is 2-0 with a 2.63 ERA and 19 strikeouts in his career against the Los Angeles Angels.

Los Angeles Angels @ Colorado Rockies Betting Trends: September 21, 2025

• Probable Starting Pitcher: Kyle Freeland      Record this season: 4-16      ERA: 5.14
• Home Record: 2-7
• Last 5 against Angels: 2-0

Why the Colorado Rockies will win

• The Angels have lost eight of their last nine games.
• The Rockies have won five of their last six games against the Angels following a loss.
• The Angels have failed to cover the run line in six of their last seven games.
• The Rockies have covered the run line in five of their last six games against the Angels following a loss.
• The Rockies have led after 5 innings in three of their last four home games against AL West opponents that held a losing record.

• Probable Starting Pitcher: Caden Dana      Record this season: 0-2      ERA: 7.45
• Road Record: 0-1
• Last 5 against Rockies: –

Why the Los Angeles Angels will win

• The Rockies have lost 22 of their last 25 games after playing the previous day.
• The road team has won four of the Rockies’ last five games.
• The Rockies have failed to cover the run line in 14 of their last 16 games after playing the previous day.
• The Angels have covered the run line in four of their last five road games against NL West opponents.
• The Angels have led after 3 innings in three of their last four games against opponents that held a losing record.
• The Angels have led after 5 innings in each of their last three day games against opponents that held a losing record.

Total Runs Facts

• Five of the Rockies’ last six games after playing the previous day have gone OVER the total runs line.
• Three of the Angels’ last four road games against NL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last four day games against AL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the Angels’ last 13 games against NL West opponents.

Colorado Rockies Player Prop Facts

• Ezequiel Tovar has recorded two or more hits in each of the Rockies’ last four day games against AL West opponents that held a losing record.
• Kyle Freeland has recorded four or more strikeouts in three of his last four appearances against AL opponents.
• Kris Bryant has hit a home run in seven of his last 29 appearances against AL West opponents.
• Tyler Freeman has recorded at least one Double in five of his last six appearances at Coors Field against AL opponents that held a losing record.

Los Angeles Angels Player Prop Facts

• Taylor Ward has hit a home run in three of the Angels’ last four games against NL West opponents.
• Chris Taylor has recorded at least one hit in each of his last seven appearances against NL West opponents that held a losing record.

Matchup/League Facts

• The Rockies rank 30th in the league for ERA this season (6.02).
• The Rockies rank 30th in the league for strikeouts this season (1034).
• The Angels rank 30th in the league for strikeouts against this season (1559).
• The Angels rank 30th in the league for walks allowed this season (599).

Los Angeles Angels vs Colorado Rockies Prediction

Another game between two awful teams, I don’t want to get involved at all. You need to call a 1-800 number if looking to bet this game. With that said, I’d lean over if forced to pick. Dana has allowed 15 hits and 11 earned runs in his last 13.1 innings. Freeland has a 5.14 ERA and 1.47 WHIP on the season, and he has a 6.14 ERA and .327 allowed batting average at home. We should see runs. Give me the over.