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Los Angeles Angels vs Cleveland Guardians Prediction 6/1/25 MLB Picks

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Cleveland Guardians (31-26) vs Los Angeles Angels (26-31)

June 1, 2025 at 01:40 PM EDT

The Line: Betting Odds: Cleveland Guardians -170 / Los Angeles Angels +142 — Over/Under: 8.5

(Get latest betting odds)

The Los Angeles Angels and Cleveland Guardians meet Sunday in MLB action at Progressive Field. Here’s a Los Angeles Angels vs Cleveland Guardians Prediction. This article will include a Los Angeles Angels vs Cleveland Guardians Pick.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 26-31 on the year and play the Red Sox, Mariners, and Athletics next. The Los Angeles Angels are batting .227 on the season, have a .288 OBP, and a .408 slugging percentage. The Los Angeles Angels pitching staff has a 4.82 ERA and a 1.51 WHIP. Nolan Schanuel leads the Los Angeles Angels with 53 hits and 14 RBI, while Taylor Ward and Logan O’Hoppe have combined for 94 hits and 68 RBI. 

Jack Kochanowicz gets the ball for the Los Angeles Angels, and he is 3-6 with a 5.07 ERA and 40 strikeouts this season. This will be Kochanowicz’s second career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 31-26 on the year and play the Yankees, Astros, and Reds next. The Cleveland Guardians are batting .235 on the season, have a .307 OBP, and a .382 slugging percentage. The Cleveland Guardians pitching staff has a 4.14 ERA and a 1.40 WHIP. Steven Kwan leads the Cleveland Guardians with 70 hits and 20 RBI while Jose Ramirez and Carlos Santana have combined for 115 hits and 57 RBI.

Gavin Williams gets the ball for the Cleveland Guardians, and he is 4-3 with a 4.27 ERA and 60 strikeouts this season. This will be Williams’ second career game against the Los Angeles Angels.

Why the Cleveland Guardians will win

  • The Angels have lost each of their last 10 day games against the Guardians at Progressive Field following a road loss.
  • The Guardians have won each of their last nine day games against the Angels following a home win.
  • The Angels have failed to cover the run line in each of their last eight games against AL Central opponents following a road loss.
  • The Guardians have covered the run line in eight of their last nine day games against AL West opponents following a home win.

Why the Los Angeles Angels will win

  • The Guardians have lost each of their last three games as favorites against AL West opponents following a win.
  • The Angels have won eight of their last nine road games.
  • The Angels have covered the run line in eight of their last nine games as road underdogs.
  • The Guardians have failed to cover the run line in each of their last four games as favorites against the Angels following a win.
  • The Angels have led after 3 innings in six of their last seven games at Progressive Field against American League opponents that held a winning record.
  • The Angels have led after 5 innings in eight of their last nine games as road underdogs.

Cleveland Guardians Player Prop Facts

  • Jose Ramirez has hit a home run in three of the Guardians’ last four home games against opponents that held a losing record.
  • Carlos Santana has scored a run in each of his last seven appearances with the Guardians as home favorites against the Angels.
  • Carlos Santana has recorded at least one hit in each of his last 11 appearances with his team as a home favorite against AL West opponents.
  • Carlos Santana has recorded a Single in each of his last seven appearances with his team as a home favorite against AL West opponents.
  • Jose Ramirez has recorded at least one RBI in each of the Guardians’ last four day games against AL West opponents that held a losing record.

Los Angeles Angels Player Prop Facts

  • Jorge Soler has hit a home run in three of the Angels’ last four games against the Guardians.
  • Taylor Ward has scored at least one run in seven of the Angels’ last eight games as road underdogs.
  • Taylor Ward has recorded at least one hit in each of the Angels’ last 10 games as road underdogs.
  • Logan O’Hoppe has recorded at least one Single in each of his last seven appearances with the Angels as underdogs against the Guardians.
  • Taylor Ward has recorded at least one RBI in seven of the Angels’ last eight games as road underdogs.

Los Angeles Angels vs Cleveland Guardians Prediction

The Angels continue to have a rough week where they can’t buy a win and I doubt things change with Kochanowicz on the mound. Kochanowicz has a 5.07 ERA and 1.52 WHIP on the season, and he has a 5.63 ERA and .285 allowed batting average in 32 road innings. Williams has been hittable this season as well, but he is coming off a decent May where he allowed 21 hits and nine runs in 24.2 innings. I just don’t have confidence in the Angels and their pitching matchup isn’t attractive. Give me the Guardians and the somewhat reasonable price.

Randy Chambers's Pick: Cleveland Guardians -170

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