Sep 17, 2025; Kansas City, Missouri, USA; Kansas City Royals starting pitcher Cole Ragans (55) delivers a pitch against the Seattle Mariners during the first inning at Kauffman Stadium. Mandatory Credit: Denny Medley-Imagn Images

Kansas City Royals vs Oakland Athletics Prediction 9/28/2025 Today’s MLB Picks

Pick details

Kansas City (81-80) vs Oakland (76-85)

September 28, 2025 at 03:05 PM EDT

The Line: Betting Odds: Oakland -110 — Over/Under: 8.5

(Get latest betting odds)

In this article, we will formulate a Royals vs Athletics Prediction for this MLB game on Saturday, September 28th at the Sutter Health Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 76-85 record this season and are sitting on the last place of the AL West. The Athletics have a 36-44 home record and are 77-77 in over/under. They are coming off a 2-4 home defeat by the Royals. Under is 8-3-1 in their last 12 games.

The Athletics have a .253 batting average this season, .318 OBP and .431 Slugging percentage. Athletics’ pitching staff has a 4.68 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 164 hits, while Jacob Wilson is the team’s best hitter with a .311 batting average. Tyler Soderstrom adds a team-high 93 RBI, while Nick Kurtz adds a team-high 35 home runs. 

Brady Basso (R) is the projected starter for the Athletics, and he has a 1-0 record,1.74 ERA and 1.55 WHIP.

Kansas City Royals Preview

The Kansas City Royals have an 81-80 record this season and are sitting on the second place of the AL Central. The Royals have a 38-42 road record and are 70-90 in over/under. They are coming off a 4-2 road win over the A’s.

The Royals have a .246 batting average this season, .308 OBP and .395 Slugging percentage. Kansas’ pitching staff has a 3.74 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 183 hits, and he is the team’s best hitter with a .296 batting average. Vinnie Pasquantino leads the team in RBI, with 113, and a team-high 32 home runs.

Cole Ragans (R) is the projected starter for the Royals, and he has a 3-3 record, 5.02 ERA and 1.22 WHIP.

Kansas City Royals @ Athletics Betting Trends: September 28, 2025

  • Probable Starting Pitcher: Brady Basso      Record this season: 1-0      ERA: 1.74
  • Home Record: 1-0
  • Last 5 against Royals: –

Why the Athletics will win

  • The Athletics have won 10 of their last 11 home games against the Royals following a loss.
  • The Royals have lost 10 of their last 11 games following a road win.
  • The Athletics have covered the run line in nine of their last 10 games against teams that held a winning record.
  • The Royals have failed to cover the run line in eight of their last nine day games following a win.
  • The Royals have lost the first inning in three of their last four day games against opponents that held a losing record.
  • The Royals have trailed after 5 innings in nine of their last 10 day games against American League opponents.
  • The Royals have trailed after 3 innings in each of their last four day games.

  • Probable Starting Pitcher: Cole Ragans      Record this season: 3-3      ERA: 5.02
  • Road Record: 2-1
  • Last 5 against Athletics: 2-1

Why the Kansas City Royals will win

  • The Athletics have lost nine of their last 10 day games against AL Central opponents that held a winning record.
  • The road team has won five of the last six games between the Royals and Athletics.
  • The Athletics have failed to cover the run line in nine of their last 10 day games against AL Central opponents following a loss.
  • The Royals have covered the run line in 13 of their last 14 Sunday road games.
  • The Athletics have lost the first inning in each of their last six Sunday games.
  • The Athletics have trailed after 5 innings in nine of their last 10 day games against AL Central opponents that held a winning record.
  • The Athletics have trailed after 3 innings in nine of their last 10 day games against AL Central opponents that held a winning record.

Total Runs Facts


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  • Seven of the Athletics’ last eight home games against American League opponents have gone UNDER the total runs line.
  • Four of the Royals’ last five day games against AL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last six day games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Royals’ last 10 day games against AL West opponents.

Athletics Player Prop Facts

  • Zack Gelof has hit a home run in each of his last three appearances against the Royals.
  • Shea Langeliers has recorded at least one hit in each of his last 13 appearances against AL Central opponents.
  • Shea Langeliers has recorded a Double in seven of his last eight home appearances against AL Central opponents.

Kansas City Royals Player Prop Facts

  • Bobby Witt Jr. has recorded a Double in each of the Royals’ last three day games against AL West opponents that held a losing record.
  • Vinnie Pasquantino has hit a home run in each of the Royals’ last two day games against AL West opponents that held a losing record.
  • Bobby Witt Jr. has recorded at least one hit in 15 of his last 16 appearances in day games against AL teams that held a losing record.

Matchup/League Facts

  • The Athletics rank 2nd in the league for doubles this season (294).
  • The Athletics rank 28th in the league for walks allowed this season (566).
  • The Royals rank 2nd in the league for strikeouts against this season (1088).
  • The Royals rank 29th in the league for walks this season (431).

Royals vs Athletics Prediction

The Athletics are 6-2 in their last 8 meetings against the Royals, and are 3-2 in their last 5 home meetings. Under is 9-3 in their last 12 meetings.  

In this Royals vs Athletics Prediction, both teams are coming at a pickem price. This is the final regular season game between two teams that have nothing to play for. The A’s are going for a bullpen game, while the Royals are putting Ragans on the mound, who has been bad this season and in terrible form lately. But both teams cannot hit lefties at all, as they average 7.5 runs per game combined against left-handed pitching, and the previous two games of this series were low-scoring ones, with 7 and 6 total runs. I expect another low-scoring affair, so take the under 8.5 in this one.

Nikos Lagouretos's Pick: Under 8.5

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