Houston Astros vs Seattle Mariners Prediction 4/13/2026 Today’s MLB Picks

The Houston Astros and Seattle Mariners meet Monday in MLB action at T-Mobile Park. Here’s a Houston Astros vs. Seattle Mariners Prediction. This article will include a Houston Astros vs. Seattle Mariners Pick.

Houston Astros Betting Preview

The Houston Astros are 6-10 on the year and play the Rockies and Cardinals next. The Houston Astros are batting .275 on the season and have a .369 OBP, and a .454 slugging percentage. The Houston Astros pitching staff has a 6.49 ERA and a 1.70 WHIP. Jose Altuve leads the Houston Astros with 19 hits and 6 RBI, while Christian Walker and Yordan Alvarez have combined for 35 hits and 27 RBI.

Mike Burrows gets the ball for the Houston Astros, and he is 1-2 with a 5.63 ERA and 15 strikeouts this season. This will be Burrows’ second career game against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 7-9 on the year and play the Rangers and Padres next. The Seattle Mariners are batting. 198 on the season, have a .312 OBP, and have a .324 slugging percentage. The Seattle Mariners pitching staff has a 3.01 ERA and a 1.04 WHIP. Randy Arozarena leads the Seattle Mariners with 16 hits and 7 RBI while Cole Young and Julio Rodriguez have combined for 26 hits and 14 RBI.

George Kirby gets the ball for the Seattle Mariners, and he is 1-2 with a 3.60 ERA and 16 strikeouts this season. Kirby is 4-1 with a 2.15 ERA and 48 strikeouts in his career against the Houston Astros.

Why the Seattle Mariners will win

• The Mariners have won each of their last 13 games at T-Mobile Park against teams that held a losing record.
• The Astros have lost each of their last seven road games.
• The Astros have failed to cover the run line in six of their last seven road games.
• The Mariners have covered the run line in five of their last six games as favorites against the Astros.
• The Mariners have led after 5 innings in five of their last six games against the Astros.
• The Astros have lost the first inning in each of their last four road games.

Why the Houston Astros will win

• The underdogs have won seven of the Astros’ last 10 games.
• The Mariners have lost four of their last six games as favorites following a win.
• The Astros have covered the run line in 19 of their last 22 games as underdogs against American League opponents following a road loss.
• The Mariners have failed to cover the run line in five of their last six games as favorites following a win.

Total Runs Facts

• Seven of the Astros’ last eight games against AL West opponents have gone OVER the total runs line.
• Four of the last five games between the Astros and Mariners have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last seven games as underdogs against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Mariners’ last eight games against AL West opponents.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit a home run in three of the Mariners’ last five games as favorites against the Astros.
• George Kirby has recorded six or more strikeouts in six of his last seven home appearances.
• Julio Rodriguez has recorded at least one hit in each of the Mariners’ last eight games against the Astros.
• George Kirby has recorded a win in eight of his last nine appearances in day games against AL West teams that held a losing record.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in three of the Astros’ last four road games against AL West opponents.
• Jose Altuve has recorded at least one hit in 27 of his last 28 road appearances against the Mariners after playing the previous day.
• Yordan Alvarez ranks T2nd in the league in Home Runs (6) this season.

Matchup/League Facts

• The Mariners rank 2nd in the league for walks allowed this season (35).
• The Mariners rank 28th in the league for hits this season (102).
• The Astros rank 1st in the league for doubles this season (42).
• The Astros rank 1st in the league for on-base percentage this season (.369).

Houston Astros vs Seattle Mariners Prediction

As I said in previous write-ups, the Astros are a tough sell given their pitching situation. The Astros are horrendous right now and Burrows has played a role in the disaster. Burrows has a 5.63 ERA and 1.75 WHIP through 16 innings. The Mariners have used this series to find their bats and this talented lineup is hard to stop once they get going. I have little use for the Astros and these issues on the bump. Give me the Mariners at home with the quick turnaround.

Randy Chambers's Pick: Seattle Mariners