Giants vs Cubs Prediction 6/5/2026 Today’s MLB Picks

In this article we will formulate a Giants vs Cubs prediction for this MLB game on Friday, June 5th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

San Francisco Giants Betting Preview

The San Francisco Giants are 25-38 this year after they split four games with the Brewers by scores of 2-16, 3-8, 1-0, and 12-9. In game four, San Francisco scored six runs in the first three innings and they eventually led 12-3 in the seventh, before nearly blowing the lead. The Giants recorded 20 hits and they committed one error in the game, while they were led by Haase, who went 1-4 with one home run and four RBIs. Houser allowed five hits and two earned runs over 4.1 innings, while Hentges picked up the win and Kilian got the save. Prior to that series, San Francisco lost two out of three against the Rockies and all three against the Diamondbacks. 

This season, San Francisco has a 4.58 ERA with a 1.41 WHIP and a .253 opponent batting average, while they have scored 250 runs with a .256 batting average and a .304 on base percentage. Casey Schmitt has led the Giants with 13 home runs and 35 RBIs, while Rafael Devers has added seven home runs and 30 RBIs. The projected starting pitcher for San Francisco is Robbie Ray, who is 3-6 with a 4.45 ERA and a 1.40 WHIP over 62.2 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 33-30 this season after they lost two out of three against the Athletics by scores of 1-2, 4-5, and 7-6. In game three, Chicago trailed 6-1 in the seventh inning, but they rallied and ended up with a walk-off win. The Cubs recorded 11 hits in the game and they were led by Happ, who went 2-4 with one home run and three RBIs. Imanaga allowed six hits and six earned runs over 6.0 innings, while Rolison picked up the win in relief. Prior to that series, Chicago lost two out of three against the Cardinals and split four games with the Pirates. 

This season, Chicago has a 4.17 ERA with a 1.23 WHIP and a .238 opponent batting average, while they have scored 296 runs with a .240 batting average and a .333 on base percentage. Michael Busch has led the Cubs with six home runs and 36 RBIs, while Ian Happ has added 14 home runs and 34 RBIs. The projected starting pitcher for Chicago is Edward Cabrera, who is 3-2 with a 4.00 ERA and a 1.35 WHIP over 54.0 innings pitched this season. 

Why the Chicago Cubs will win

• The Cubs have won each of their last 10 games at Wrigley Field against National League opponents that held a losing record.
• The Giants have lost eight of their last 10 games against National League opponents that held a winning record.
• The Cubs have covered the run line in nine of their last 10 games at Wrigley Field against National League opponents that held a losing record.
• The Giants have failed to cover the run line in four of their last five games against National League opponents following a win.
• The Giants have trailed after 5 innings in eight of their last 10 games at Wrigley Field against National League opponents that held a winning record.

Why the San Francisco Giants will win

• The Giants have won each of their last seven day games against NL Central opponents that held a winning record.
• The Cubs have lost 10 of their last 12 games as favorites.
• The Cubs have failed to cover the run line in each of their last nine games at Wrigley Field.
• The Giants have covered the run line in each of their last eight day games against NL Central opponents following a road win.
• The Cubs have trailed after 3 innings in three of their last four day games.
• The Giants have led after 5 innings in five of their last six road day games.

Total Runs Facts

• Four of the Giants’ last five games have gone OVER the total runs line.
• Six of the Cubs’ last eight games as favorites against the Giants have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Cubs’ last seven games as favorites against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of Robbie Ray’s last three appearances as a starter.

Chicago Cubs Player Prop Facts

• Edward Cabrera has recorded six or more strikeouts in each of his five previous appearances with his team as a favorite against NL West opponents.
• Seiya Suzuki has hit a home run in each of the Cubs’ last three home games against NL opponents that held a losing record.
• Alex Bregman has recorded at least one hit in each of the Cubs’ last eight games against NL opponents.

San Francisco Giants Player Prop Facts

• Casey Schmitt has hit a home run in four of the Giants’ last six day games against opponents that held a winning record.
• Jung Hoo Lee has recorded at least one hit in each of his last 12 appearances.

Giants vs Cubs Prediction 

San Francisco comes into this matchup after managing a series split with the Brewers, but they have allowed 8+ runs in three of their last four games. The Giants are 13-22 on the road this year, while the Cubs are 19-13 at home. Chicago has lost three of their last four games and they were very lucky to win on Thursday night. The Cubs are starting Cabrera, who has allowed 3+ earned runs in four of his last five outings, while Ray has allowed 1, 4, 9, and 3 earned runs in his last four starts. I think we are going to see plenty of runs in this game and even with a high number, I like the over here.

David Racey's Pick: Over 11