Aug 21, 2025; Chicago, Illinois, USA; Milwaukee Brewers second baseman Brice Turang (2) celebrates with designated hitter Christian Yelich (22) after hitting a two-run home run against the Chicago Cubs during the second inning at Wrigley Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

Giants vs Brewers Prediction 8/23/2025 Today’s MLB Picks

Pick details

San Francisco (61-68) vs Milwaukee (81-48)

August 23, 2025 at 07:10 PM EDT

The Line: Betting Odds: Milwaukee -1.5 — Over/Under: +7.5

(Get latest betting odds)

In this article we will formulate a Giants vs Brewers prediction for this MLB game on Saturday, August 23rd at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

San Francisco Giants Betting Preview

The San Francisco Giants are 61-68 this year after they lost game one by a score of 5-4 on Friday night. San Francisco was able to tie the game at four in the top of the ninth, but allowed a run in the bottom half of the inning for the loss. The Giants recorded five hits in the game and they were led by Adames, who went 2-4 with two home runs and two RBIs in the loss. SF started Whisenhunt, who allowed four hits and two earned runs over 4.0 innings, while Lucchesi allowed two earned runs in relief. 

Prior to this series, the Giants lost three out of four against the Padres and two out of three against the Rays. San Francisco has lost 11 of their last 13 games and they are fourth in the NL West standings. The San Francisco pitching staff has a 3.76 ERA with a 1.29 WHIP, and a .245 opponent batting average, while the offense has scored 519 runs with a .231 batting average and a .308 on base percentage this season. Wilmer Flores has led San Francisco with 13 home runs and 63 RBIs, while Willy Adames has added 22 home runs and 65 RBIs this year. The projected starting pitcher for San Francisco is Logan Webb, who is 11-9 with a 3.19 ERA and a 1.22 WHIP over 160.2 innings pitched this year. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 81-48 this season after they won game one in dramatic fashion on Friday night. Milwaukee trailed 2-0 in the second inning, but they scored the next four runs in the game, before needing a run in the ninth to get the win. The Brewers recorded seven hits in the game and they were led by Contreras, who went 2-4 with one home run and two RBIs in the win. Milwaukee started Quintana, who allowed two hits and two earned runs over 5.1 innings, while Megill blew the save, but also got the win. 

Prior to this series, the Brewers lost three out of five against the Cubs, but did win two out of three against the Reds before that. Milwaukee has lost three of their last five games and they are currently leading the NL Central standings. The Milwaukee pitching staff has a 3.57 ERA with a 1.22 WHIP and a .228 opponent batting average, while the offense has scored 662 runs with a .257 batting average and a .332 on base percentage this season. Christian Yelich has led Milwaukee with 26 home runs and 87 RBIs, while William Contreras has added 14 home runs and 63 RBIs this year. The projected starting pitcher for Milwaukee is Freddy Peralta, who is 15-5 with a 2.78 ERA and a 1.10 WHIP over 142.2 innings pitched this season.

Why the Brewers will beat the Giants 

  • The Brewers have won each of their last 11 games against National League opponents that held a losing record.
  • The Giants have lost nine of their last 10 games against National League opponents.
  • The Brewers have covered the run line in each of their last 10 night games against National League opponents following a home win.
  • The Giants have failed to cover the run line in eight of their last 10 games against National League opponents after playing the previous day.
  • The Giants have trailed after 5 innings in three of their last four road games against National League opponents that held a winning record.

    Why the Giants will beat the Brewers 

    • The Giants have won four of their last six games as underdogs against NL Central opponents following a loss.
    • The Brewers have lost three of their last four night games against the Giants following a home win.
    • The Giants have covered the run line in seven of their last eight road games against NL Central opponents following a loss.
    • The Brewers have failed to cover the run line in each of their last five night games against the Giants following a win.
    • The Giants have led after 3 innings in four of their last five games as underdogs against NL Central opponents.

    Total Runs Facts

    • Seven of the Brewers’ last nine home games after playing the previous day have gone OVER the total runs line.
    • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last four night games.
    • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Brewers’ last five home games.

    Giants vs Brewers Prediction 

    San Francisco comes into this matchup trying to snap their four game losing streak, but they have allowed 26 runs in those four losses. The Giants are 31-35 on the road this year, while the Brewers are 43-20 at home. Milwaukee has won two games in a row and they are starting Peralta, who has allowed a total of one earned run in his last three outings. The Giants are going with Webb, who has allowed one earned run or fewer in three of his last four starts. Take the under in this contest. 

    David Racey's Pick: Under 7.5

    Need More? Get Premium Picks

    Hot Cappers

    Latest Picks & Game Previews

    • Sofia Kenin vs Laura Siegemund Prediction 9/15/2025 Today’s Tennis Picks

      September 15, 2025

    • Tampa Bay Buccaneers vs Houston Texans Prediction 9/15/2025 Today’s NFL Picks

      September 15, 2025

    • Los Angeles Chargers vs Las Vegas Raiders Prediction 9/15/2025 Today’s NFL Picks

      September 15, 2025