Sep 2, 2025; Pittsburgh, Pennsylvania, USA;  Los Angeles Dodgers two-way player Shohei Ohtani (17) asks for time-out in his at bat against the Pittsburgh Pirates during the seventh inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images

Dodgers vs Pirates Prediction 9/3/2025 Today’s MLB Picks

Pick details

Los Angeles (78-60) vs Pittsburgh (62-77)

September 3, 2025 at 06:40 PM EDT

The Line: Betting Odds: Pittsburgh +150 — Over/Under: +8.5

(Get latest betting odds)

In this article we will formulate a Dodgers vs Pirates prediction for this MLB game on Wednesday, September 3rd at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 78-60 this year after they lost game one by a score of 9-7 on Tuesday night. Los Angeles fell behind 4-0 in the first inning and they played catch up all night, but came up short in the ninth for the loss. The Dodgers recorded 12 hits in the game and they were led by Ohtani, who went 3-5 with one home run and two RBIs in the loss. Los Angeles started Kershaw, who allowed four hits and four earned runs over 5.0 innings, while Henriquez picked up the loss in relief. 

Prior to this series, the Dodgers lost two out of three against the Diamondbacks, but did win all three against the Reds before that. Los Angeles has lost three of their last four games and they are currently first in the NL West standings. The Los Angeles pitching staff has a 4.12 ERA with a 1.29 WHIP and a .241 opponent batting average, while their offense has scored 707 runs with a .253 batting average and a .329 on base percentage this season. Shohei Ohtani has led LA with 46 home runs and 87 RBI’s, while Andy Pages has added 24 home runs and 78 RBIs this year. The projected starting pitcher for Los Angeles is Shohei Ohtani, who is 1-1 with a 4.18 ERA and a 1.21 WHIP over 32.1 innings pitched this year. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 62-77 this season after they won game one by a score of 9-7 on Tuesday evening. Pittsburgh blew an early 4-0 lead, but they retook the lead in the sixth and never looked back in the victory. The Pirates recorded eight hits and they committed one error in the game, while they were led by Pham and Triolo, who both had two RBIs in the win. Pittsburgh started Mlodzinski, who allowed two hits and one earned run over 2.0 innings, while Chandler got the win and Santana picked up the save. 

Prior to this series, the Pirates won two out of three against the Red Sox and split four games with the Cardinals. Pittsburgh has won three of their last four games and they are last in the NL Central standings. The Pittsburgh pitching staff has a 3.91 ERA with a 1.22 WHIP and a .237 opponent batting average, while their offense has scored 509 runs with a .234 batting average and a .308 on base percentage this season. Oneil Cruz has led Pittsburgh with 19 home runs and 54 RBIs, while Bryan Reynolds has added 14 home runs and 68 RBIs this year. The projected starting pitcher for Pittsburgh is Braxton Ashcraft, who is 4-2 with a 2.58 ERA and a 1.15 WHIP over 52.1 innings pitched this season. 

Why the Dodgers will beat the Pirates

The Pirates have lost seven of their last eight games at PNC Park against NL West opponents that held a winning record.
The Dodgers have won five of their last six road games against National League opponents following a loss.
The Dodgers have covered the run line in five of their last six games as road favorites against the Pirates following a loss.
The Pirates have failed to cover the run line in three of their last four home games against NL West opponents that held a winning record.

Total Runs Facts

Five of the Pirates’ last six night games against NL West opponents have gone OVER the total runs line.
Four of the Dodgers’ last five games as favorites against the Pirates have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last six night games between the Dodgers and Pirates.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Dodgers’ last nine night games.

Pittsburgh Pirates Player Prop Facts

Tommy Pham has recorded a Double in three of his last four home appearances.
Andrew McCutchen has hit a home run in three of the Pirates’ last five games against NL West opponents that held a winning record.
Tommy Pham has recorded at least one hit in each of his last 10 Wednesday appearances with the Pirates as underdogs.

Los Angeles Dodgers Player Prop Facts

Shohei Ohtani has hit a home run in each of the Dodgers’ last two road games.
Andy Pages has recorded at least one hit in each of the Dodgers’ last eight games.
Shohei Ohtani has recorded at least one Double in each of the Dodgers’ last three games against the Pirates.
Shohei Ohtani has recorded six or more strikeouts in four of his last five appearances in night games against NL teams that held a losing record.

Dodgers vs Pirates Prediction 

The Pirates were able to stay hot with another win on Tuesday to start this series, and they have won nine of their last twelve games. Pittsburgh is 40-30 at home this year, while LA is 33-34 on the road. The Dodgers have struggled recently and they are starting Ohtani, who has allowed one earned run or fewer in two of his last four outings. The Pirates are starting Ashcraft, who has allowed one earned run or fewer in four straight starts. I think Ashcraft has been the better starting pitcher, but I will back the Dodgers on the run line here.

David Racey's Pick: Dodgers -1.5

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