Sep 13, 2025; Seattle, Washington, USA; Seattle Mariners designated hitter Jorge Polanco (7) runs the bases after hitting a 2-RBI double against the Los Angeles Angels during the first inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images

Colorado Rockies vs Seattle Mariners Prediction 9/25/2025 Today’s MLB Picks

Pick details

Colorado (43-115) vs Seattle (89-69)

September 25, 2025 at 09:40 PM EDT

The Line: Betting Odds: Seattle — Over/Under:

(Get latest betting odds)

The Colorado Rockies and the Seattle Mariners meet Thursday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Colorado Rockies will send out Bradley Blalock here and Blalock is 2-5 with a 9.16 ERA and 26 strikeouts this season. This will be Blalock’s first career start against the Mariners. The Seattle Mariners did not have a starting pitcher announced at the time that this article was posted.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from a 9-2 loss at the hands of the Mariners last time out to sit at 43-115 this season. After this series, the Rockies will finish the regular season with a division series against the San Francisco Giants.

Rockies Looking To Avoid Sweep

Hunter Goodman leads the Rockies with 144 hits including 26 doubles, 5 triples, 30 home runs and 88 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 132 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 15 home runs, 26 doubles, 52 RBIs, 5 triples and 17 stolen bases. Brenton Doyle has 113 hits with 21 doubles, 14 home runs, 56 RBIs and 17 stolen bases. Mickey Moniak has 114 hits with 18 doubles, 8 triples and 24 home runs with 68 RBIs. Tyler Freeman also has 106 hits with 20 doubles and 18 stolen bases so far this season.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their win over Colorado from Wednesday to sit at 89-69 on the year. After this set, the Mariners will take on the Los Angeles Dodgers in an interleague series at home.

Mariners Win 6th In A Row, Clinch First AL West Crown Since 2001

Jorge Polanco has 122 hits including 30 doubles, 24 home runs and 74 RBIs while Cal Raleigh has 141 hits with 22 doubles, a team-high 58 home runs and 121 RBIs. Randy Arozarena has 138 hits with 30 doubles, 27 home runs, 73 RBIs and 28 stolen bases. Julio Rodriguez also has 171 hits with 31 doubles, 4 triples, 31 home runs, 94 RBIs and 28 stolen bases. J.P Crawford has 148 hits with 24 doubles, 12 home runs and 58 RBIs.

Colorado Rockies @ Seattle Mariners Betting Trends: September 25, 2025

  • Probable Starting Pitcher: TBD

Why the Seattle Mariners will win


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  • The Mariners have won each of their last 10 home games.
  • The Rockies have lost 12 of their last 13 road games against AL West opponents that held a winning record.
  • The Mariners have covered the run line in each of their last six games against National League opponents after playing the previous day.
  • The Rockies have failed to cover the run line in seven of their last eight road games after playing the previous day.
  • The Rockies have trailed after 3 innings in seven of their last eight road games.
  • The Mariners have won the first inning in three of their last four home games.
  • The Mariners have led after 5 innings in five of their last six games.
  • Probable Starting Pitcher: Bradley Blalock      Record this season: 2-5      ERA: 9.16
  • Road Record: 0-1
  • Last 5 against Mariners: –

Why the Colorado Rockies will win

  • The road team has covered the run line in five of the Mariners’ last six games.
  • The Mariners have failed to cover the run line in five of their last six games against NL West opponents that held a losing record.
  • The Mariners have trailed after 3 innings in five of their last six night games against NL West opponents.

Total Runs Facts

  • Five of the Rockies’ last six road games against American League opponents have gone UNDER the total runs line.
  • Five of the Mariners’ last six night games against NL West opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last 10 Thursday night games at T-Mobile Park.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Rockies’ last five road games.

Seattle Mariners Player Prop Facts

  • Cal Raleigh has hit at least one home run in three of the Mariners’ last four games.
  • J.P. Crawford has recorded at least one hit in each of the Mariners’ last 10 Thursday games.
  • Jorge Polanco has recorded at least one Double in eight of the Mariners’ last 10 home games.

Colorado Rockies Player Prop Facts

  • Kris Bryant has hit a home run in three of his last six appearances in night games against AL teams that held a winning record.
  • Tyler Freeman has recorded at least one hit in each of his last 14 appearances against AL opponents that held a winning record.

Matchup/League Facts

  • The Mariners rank 2nd in the league for home runs this season (236).
  • The Mariners rank 29th in the league for doubles this season (229).
  • The Rockies rank 30th in the league for on-base percentage this season (.294).
  • The Rockies rank 30th in the league for walks this season (387).

Colorado Rockies vs. Seattle Mariners Prediction

I’m backing Seattle here. It’s a lean because now that the Mariners have clinched the division, who knows what Seattle will do here, but there’s still work to do as the top-2 spots and the first round bye in the AL is still up for grabs and Bradley Blalock has been batting practice for whoever he has gone against this season. I think Colorado gets shelled here as Blalock gets chased early, so give me Seattle in this one.

Chris Ruffolo's Pick: Seattle -1.5


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