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Colorado Rockies vs San Francisco Giants Prediction 9/28/2025 Today’s MLB Picks
Pick details
Colorado (43-118) vs San Francisco (80-81)
September 28, 2025 at 03:05 PM EDT
The Line: Betting Odds: San Francisco -1.5 — Over/Under: +7.5
Colorado Rockies Betting Preview
The Colorado Rockies are 43-118 on the year after playing the Mariners. The Colorado Rockies are batting .237 on the season, have a .293 OBP, and a .387 slugging percentage. The Colorado Rockies pitching staff has a 5.99 ERA and a 1.58 WHIP. Hunter Goodman leads the Colorado Rockies with 149 hits and 91 RBI, while Jordan Beck and Mickey Moniak have combined for 256 hits and 121 RBI.
McCade Brown gets the ball for the Colorado Rockies, and he is 0-4 with a 7.54 ERA and 21 strikeouts this season. This will be Brown’s first career game against the San Francisco Giants.
San Francisco Giants Betting Preview
The San Francisco Giants are 80-81 on the year after playing the Cardinals. The San Francisco Giants are batting .235 on the season, have a .311 OBP, and a .386 slugging percentage. The San Francisco Giants pitching staff has a 3.87 ERA and a 1.30 WHIP. Heliot Ramos leads the San Francisco Giants with 159 hits and 69 RBI while Jung Hoo Lee and Willy Adames have combined for 278 hits and 139 RBI.
Logan Webb gets the ball for the San Francisco Giants, and he is 14-11 with a 3.30 ERA and 216 strikeouts this season. Webb is 10-3 with a 3.12 ERA and 96 strikeouts in his career against the Colorado Rockies.
Colorado Rockies @ San Francisco Giants Betting Trends: September 28, 2025
- Probable Starting Pitcher: Logan Webb Record this season: 14-11 ERA: 3.30
- Home Record: 7-4
- Last 5 against Rockies: 3-1
Why the San Francisco Giants will win
- The Rockies have lost each of their last 15 games at Oracle Park against NL West opponents that held a losing record.
- The Giants have won each of their last 13 games against the Rockies at Oracle Park following a win.
- The Rockies have failed to cover the run line in seven of their last eight day games against NL West opponents following a road loss.
- The Giants have covered the run line in 12 of their last 15 games as home favorites against the Rockies.
- The Giants have led after 5 innings in each of their last nine day games against the Rockies at Oracle Park.
- The Giants have led after 3 innings in each of their last six games against the Rockies.
- Probable Starting Pitcher: McCade Brown Record this season: 0-4 ERA: 7.54
- Road Record: 0-2
- Last 5 against Giants: –
Why the Colorado Rockies will win
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- The Giants have lost four of their last five games as home favorites after playing the previous day.
- The underdogs have won four of the Giants’ last six games.
- The Giants have failed to cover the run line in each of their last five games as home favorites after playing the previous day.
- The road team has covered the run line in four of the last five games between the Rockies and Giants.
Total Runs Facts
- Six of the Rockies’ last seven games as underdogs against National League opponents have gone OVER the total runs line.
- Six of the Giants’ last seven day games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last seven games as home favorites.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last five road games against NL West opponents.
San Francisco Giants Player Prop Facts
- Heliot Ramos has hit a home run in three of the Giants’ last four games as home favorites.
- Logan Webb has recorded seven or more strikeouts in four of his last five appearances against opponents that held a losing record.
- Wilmer Flores has recorded at least one hit in each of his last 10 appearances with the Giants as favorites against the Rockies.
- Logan Webb has recorded a win in each of his last four appearances against the Rockies at Oracle Park.
- Rafael Devers has recorded a Double in each of the Giants’ last three home games against NL West opponents that held a losing record.
Colorado Rockies Player Prop Facts
- Brenton Doyle has hit a home run in four of his last six road appearances against opponents that held a losing record.
- Ezequiel Tovar has recorded at least one hit in each of his last 11 appearances with the Rockies as underdogs against the Giants.
Colorado Rockies vs San Francisco Giants Prediction
We have one more chance to fade one of the worst teams in baseball history. There’s nothing left to say here, folks, as we’ve been betting against the Rockies all season. The Giants are finishing the season on a positive note, and Webb has been great at Oracle in his career. In 86 starts at Oracle, Webb has a 2.87 ERA and 1.14 WHIP, with 514 strikeouts. In 88 at bats against current Rockies, Webb is allowing a .227 batting average with 20 strikeouts. Give me the Giants and the RL for max betting value.
Randy Chambers's Pick: San Francisco Giants
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