Cleveland Guardians vs Tampa Bay Rays Prediction 9/6/2025 Today’s MLB Picks

The Cleveland Guardians and Tampa Bay Rays meet Saturday in MLB action at George M. Steinbrenner Field. Here’s a Cleveland Guardians vs Tampa Bay Rays Prediction. This article will include a Cleveland Guardians vs Tampa Bay Rays Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 70-70 on the year and play the Royals, White Sox, and Tigers next. The Cleveland Guardians are batting .224 on the season, have a .294 OBP, and a .369 slugging percentage. The Cleveland Guardians pitching staff has a 3.95 ERA and a 1.32 WHIP. Steven Kwan leads the Cleveland Guardians with 147 hits and 46 RBI, while Jose Ramirez and Kyle Manzardo have combined for 137 hits and 135 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 9-11 with a 4.77 ERA and 136 strikeouts this season. Bibee is 1-2 with a 4.74 ERA and 17 strikeouts in his career against the Tampa Bay Rays.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 71-70 on the year and play the White Sox, Cubs, and Blue Jays next. The Tampa Bay Rays are batting .252 on the season, have a .314 OBP, and a .403 slugging percentage. The Tampa Bay Rays pitching staff has a 3.87 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 153 hits and 76 RBI while Junior Caminero and Brandon Lowe have combined for 256 hits and 177 RBI.

Shane Baz gets the ball for the Tampa Bay Rays, and he is 9-11 with a 4.98 ERA and 156 strikeouts this season. This will be Baz’s second career game against the Cleveland Guardians.

Cleveland Guardians @ Tampa Bay Rays Betting Trends: September 6, 2025

• Probable Starting Pitcher: Shane Baz      Record this season: 9-11      ERA: 4.98
• Home Record: 6-5
• Last 5 against Guardians: 0-1

Why the Tampa Bay Rays will win

• The Guardians have lost each of their last six road games against the Rays following a win.
• The Rays have won each of their last five games against the Guardians following a home loss.
• The Guardians have failed to cover the run line in each of their last six road games against the Rays following a road win.
• The Rays have covered the run line in six of their last seven home games.
• The Guardians have trailed after 5 innings in 13 of their last 17 games as road underdogs against AL East opponents.

• Probable Starting Pitcher: Tanner Bibee       Record this season: 9-11      ERA: 4.77
• Road Record: 6-6
• Last 5 against Rays: 1-2

Why the Cleveland Guardians will win

• The underdogs have won four of the Rays’ last five games at George M. Steinbrenner Field.
• The Rays have lost three of their last four games as home favorites against American League opponents.
• The Rays have failed to cover the run line in each of their last six games against American League opponents following a home loss.
• The Guardians have covered the run line in nine of their last 11 night games against American League opponents that held a winning record.

Total Runs Facts

• Seven of the Rays’ last eight home games after playing the previous day have gone OVER the total runs line.
• Four of the Guardians’ last five road games have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Rays’ last 10 games as favorites against AL Central opponents.

Tampa Bay Rays Player Prop Facts

• Brandon Lowe has hit a home run in three of the Rays’ last six games as favorites against AL opponents.
• Yandy Diaz has recorded two or more hits in five of his last seven appearances against the Guardians after playing the previous day.
• Taylor Walls has recorded a Double in three of his last four appearances with the Rays as favorites against AL opponents.
• Yandy Diaz ranks T5th in the league in Hits (153) this season.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has recorded at least one hit in eight of his last nine road appearances against the Rays.
• Austin Hedges has hit a home run in two of his last three appearances.

Matchup/League Facts

• The Rays rank T26th in the league for walks this season (405).
• The Rays are one of only five teams in the league to rank top 10 in both steals and batting average this season.
• The Guardians rank 30th in the league for on-base percentage this season (.294).
• The Guardians rank 29th in the league for slugging percentage this season (.369).

Cleveland Guardians vs Tampa Bay Rays Prediction

Bibee is really having issues this season, which includes an August where he allowed 39 hits and 23 earned runs in 33.2 innings. In 83 road innings, Bibee has a 5.64 ERA and .271 allowed batting average. With that said, Baz hasn’t been much better with his 4.98 ERA and 1.34 WHIP, and in 72.1 home innings, he has a 6.47 ERA and .280 allowed batting average. Two hittable pitchers, we should see some fireworks on Saturday. I’ll take the over in this spot.