Cleveland Guardians vs Chicago White Sox Prediction 8/8/2025 Today’s MLB Picks

The Cleveland Guardians and the Chicago White Sox meet Friday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs. Chicago White Sox prediction.

Starting Pitching Matchup

The Cleveland Guardians will send out Tanner Bibee here and Bibee is 7-9 with a 4.51 ERA and 112 strikeouts this season. In his career, Bibee is 2-0 with a 5.40 ERA and 13 strikeouts against the White Sox. Aaron Civale will get the nod for the White Sox here and is 3-6 with a 3.99 ERA and 56 strikeouts this season. In his career, Civale is 1-0 with a 3.24 ERA and 9 strikeouts against the Guardians.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to add on to their 4-1 win over the New York Mets last time out to sit at 59-55 on the year. After this series, the Guardians will head home for a series against the Miami Marlins.

Guardians Win Three Straight & 8 Of Last 9

Steven Kwan has 122 hits as part of a .284 batting average and 9 home runs, 20 doubles and 39 RBIs. Kyle Manzardo has 74 hits with 13 doubles, 2 triples, 18 home runs and 49 RBIs as well this year. Gabriel Arias has 19 doubles but also 100 strikeouts and Manzardo has 91 strikeouts so far this season. Arias has also added 8 home runs and 40 RBIs and Jose Ramirez has chipped in 23 home runs and 61 RBIs with 32 stolen bases as well. Carlos Santana has also added 84 hits with 11 home runs and 47 RBIs as well this season.

Why the Cleveland Guardians will win

• The White Sox have lost each of their last nine night games against AL Central opponents following a road loss.
• The Guardians have won 10 of their last 11 games against the White Sox.
• The road team has covered the run line in each of the Guardians’ last six games.
• The White Sox have failed to cover the run line in four of their last five night games against teams that held a winning record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in each of the Guardians’ last two games as favorites.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Lane Thomas has recorded at least one hit in each of his 12 previous road appearances against AL Central opponents that held a losing record.
• Jose Ramirez ranks T3rd in the league in Steals (32) this season.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to rebound from their 4-3 loss at the hands of the Seattle Mariners last time out to sit at 42-73 this season. After this series, the White Sox will take on the Detroit Tigers at home.

White Sox Lose Four In A Row

Lenyn Sosa has 97 hits including 16 doubles and 45 RBIs. Andrew Benintendi has 69 hits including 13 doubles, 14 home runs, 44 RBIs and a .226 batting average while Miguel Vargas has 90 hits, 25 doubles, 13 home runs and 44 RBIs. Brooks Baldwin has also added 25 RBIs while Luis Robert Jr. has a team-high 31 stolen bases along with 46 RBIs so far this season. Chase Meidroth has added 78 hits with 11 stolen bases as well as 12 doubles this season.

Why the Chicago White Sox will win

• The underdogs have won each of the Guardians’ last four games.
• The Guardians have lost three of their last four night games at Rate Field following a win.
• The White Sox have covered the run line in each of their last seven games against American League opponents following an extra innings loss.
• The Guardians have failed to cover the run line in each of their last six games against American League opponents following a win.

Chicago White Sox Player Prop Facts

• Aaron Civale has recorded six or more strikeouts in each of his last three appearances.
• Luis Robert has recorded at least one hit in each of his last 13 appearances in night games.
• Michael A. Taylor has hit a home run in each of the White Sox’s last two games as underdogs.
• Luis Robert ranks 5th in the league in Steals (31) this season.

Total Runs Facts

• Each of the White Sox’s last five night games against AL Central opponents have gone OVER the total runs line.
• Seven of the Guardians’ last nine games as road favorites have gone UNDER the total runs line.

Cleveland Guardians vs. Chicago White Sox Prediction

I’m on the Guardians here. It’s not a game I’m rushing to bet considering that Aaron Civale has been really solid in his starts since the all-star break, but the White Sox just look like a team that the value is gone on. The Guardians are quietly doing Guardian things at this point in the year as this has always been a team that comes on strong towards the end of the year and play meaningful baseball over the final couple of months. I think it’s more of the same here in all honesty so I’ll roll with Cleveland in this one.