Sep 6, 2026; Cleveland, Ohio, USA; Cleveland Guardians shortstop Brayan Rocchio (4) celebrates with first baseman Nathaniel Lowe (46) after center fielder Daniel Schneemann (not pictured) hit a game-wining RBI single during the tenth inning against the Detroit Tigers at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images
IMAGN IMAGES via Reuters Connect

Cleveland Guardians vs Baltimore Orioles Prediction 9/7/2026 Today’s MLB Picks

Pick details

MATCHUP Cleveland Guardians Baltimore Orioles
Team Records 73-71 69-75
Spread +1.5 -199 -1.5 163
Moneyline +109 -131
Total Over 8.5 (-102) Under 8.5 (-118)
Where Oriole Park at Camden Yards, Baltimore, Maryland
When Monday, September 7, 2026
Time 01:35 PM EDT
TV MLB.TV

The Cleveland Guardians and Baltimore Orioles meet Monday in MLB action at Oriole Park. Here’s a Cleveland Guardians vs Baltimore Orioles Prediction. This article will include a Cleveland Guardians vs Baltimore Orioles Pick.

Cleveland Guardians Betting Preview


The Cleveland Guardians are 73-71 on the year and play the White Sox and Twins next. The Cleveland Guardians are batting .236 on the season, have a .313 OBP, and a .371 slugging percentage. The Cleveland Guardians pitching staff has a 3.75 ERA and a 1.26 WHIP. Chase DeLauter leads the Cleveland Guardians with 131 hits and 60 RBI, while Steven Kwan and Brayan Rocchio have combined for 247 hits and 87 RBI.

Joey Cantillo gets the ball for the Cleveland Guardians, and he is 9-8 with a 3.81 ERA and 151 strikeouts this season. Cantillo is 1-1 with a 4.91 ERA and 17 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview


The Baltimore Orioles are 69-75 on the year and play the Blue Jays and Mets next. The Baltimore Orioles are batting .234 on the season, with a .315 OBP and a .393 slugging percentage. The Baltimore Orioles pitching staff has a 4.13 ERA and a 1.34 WHIP. Pete Alonso leads the Baltimore Orioles with 144 hits and 94 RBI, while Leody Taveras and Gunnar Henderson have combined for 210 hits and 109 RBI.

Trevor Rogers gets the ball for the Baltimore Orioles, and he is 9-9 with a 4.30 ERA and 132 strikeouts this season. Rogers is 0-2 with a 6.91 ERA and 13 strikeouts in his career against the Cleveland Guardians.

Why the Baltimore Orioles will win

  • The Guardians have lost each of their last six day games against AL East opponents.
  • The Orioles have won seven of their last eight day games against AL Central opponents following a loss.
  • The Guardians have failed to cover the run line in each of their last six games.
  • The Orioles have covered the run line in each of their last seven Monday games.
  • The Guardians have trailed after 5 innings in each of their last four games as underdogs against AL East opponents.
  • The Guardians have trailed after 3 innings in each of their last four games.
  • The Guardians have lost the first inning in three of their last four games.

Why the Cleveland Guardians will win

  • The Orioles have lost each of their last six games.
  • The Guardians have won each of their last six road games.
  • The underdogs have covered the run line in each of the Guardians’ last five games.
  • The Orioles have failed to cover the run line in nine of their last 11 home games against AL Central opponents that held a winning record.
  • The Orioles have trailed after 5 innings in nine of their last 11 day games against AL Central opponents.
  • The Guardians have led after 3 innings in five of their last six day games against AL East opponents that held a losing record.

Total Runs Facts

  • Nine of the Guardians’ last 10 road games following an extra-innings win have gone UNDER the total runs line.
  • Six of the Orioles’ last seven games have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of the Guardians’ last six road games against AL East opponents.
  • There has been no run scored during the first inning in nine of Trevor Rogers’ last 10 appearances as a starter.

Baltimore Orioles Player Prop Facts

  • Carlos Narvaez has recorded at least one hit in each of his seven previous appearances in day games against AL Central teams that held a winning record.
  • Trevor Rogers has recorded six or more strikeouts in each of his last six appearances with the Orioles as favorites.
  • Trevor Rogers has recorded a win in four of his last five appearances in day games against AL teams that held a winning record.
  • Colton Cowser has hit a home run in three of the Orioles’ last four day games against opponents that held a winning record.
  • Pete Alonso ranks 9th in the league in Home Runs (33) this season.

Cleveland Guardians Player Prop Facts

  • Jo Adell has hit a home run in each of the Guardians’ last two games as road underdogs.
  • Joey Cantillo has recorded six or more strikeouts in four of his last five road appearances against AL opponents that held a losing record.
  • Steven Kwan has recorded at least one hit in each of his last eight appearances with the Guardians as road underdogs.
  • Jose Ramirez ranks T6th in the league in Steals (31) this season.

Matchup/League Facts

  • The Orioles rank 27th in the league for strikeouts against this season (1332).
  • The Orioles rank 4th in the league for walks this season (531).
  • The Guardians rank 29th in the league for home runs this season (134).
  • The Guardians rank 29th in the league for slugging percentage this season (.371).

Cleveland Guardians vs Baltimore Orioles Prediction


The Orioles are coming off a horrible week that has put them on the back burner in terms of the playoff race. The Guardians are in far better shape and playing the better ball overall. Cantillo has also been stronger than Rogers with a 3.81 ERA and 1.48 WHIP through 141.2 innings. The fact that you can get the Guardians in this spot at a plus-money price feels too good to be true. Who is laying juice on the O’s in their current form? Not I. Give me the Guardians.

Randy Chambers's Pick: Cleveland Guardians

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