Aug 6, 2025; Pittsburgh, Pennsylvania, USA;  Pittsburgh Pirates designated hitter Andrew McCutchen (22) hits a single against the San Francisco Giants during the eighth inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images

Cincinnati Reds vs Pittsburgh Pirates Prediction 8/7/2025 Today’s MLB Picks

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Cincinnati (60-55) vs Pittsburgh (49-66)

August 7, 2025 at 06:40 PM EDT

The Line: Betting Odds: Pittsburgh -1.5 — Over/Under: +7

(Get latest betting odds)

The Cincinnati Reds and Pittsburgh Pirates meet Thursday in MLB action at PNC Park. Here’s a Cincinnati Reds vs Pittsburgh Pirates Prediction. This article will include a Cincinnati Reds vs Pittsburgh Pirates Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 60-55 on the year and play the Phillies, Brewers, and Angels next. The Cincinnati Reds are batting .246 on the season, have a .318 OBP, and a .390 slugging percentage. The Cincinnati Reds pitching staff has a 3.87 ERA and a 1.24 WHIP. Elly De La Cruz leads the Cincinnati Reds with 123 hits and 73 RBI, while TJ Friedl and Spencer Steer have combined for 201 hits and 87 RBI. 

Brady Singer gets the ball for the Cincinnati Reds, and he is 9-8 with a 4.36 ERA and 111 strikeouts this season. Singer is 2-2 with a 5.66 ERA and 18 strikeouts in his career against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 49-66 on the year and play the Brewers, Cubs, and Blue Jays next. The Pittsburgh Pirates are batting .232 on the season, have a .303 OBP, and a .346 slugging percentage. The Pittsburgh Pirates pitching staff has a 3.88 ERA and a 1.22 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 100 hits and 53 RBI while Andrew McCutchen and Isiah Kiner-Falefa have combined for 180 hits and 69 RBI.

Paul Skenes gets the ball for the Pittsburgh Pirates, and he is 6-8 with a 2.02 ERA and 154 strikeouts this season. Skenes is 3-0 with a 0.53 ERA and 25 strikeouts in his career against the Cincinnati Reds.

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last 12 games at PNC Park against teams that held a winning record.
  • The Reds have lost seven of their last eight night games against National League opponents following a road loss.
  • The Pirates have covered the run line in eight of their last nine games against teams that held a winning record.
  • The Reds have failed to cover the run line in each of their last five night games against National League opponents following a road loss.
  • The Reds have trailed after 3 innings in five of their last six games as road underdogs against NL Central opponents.
  • The Reds have trailed after 5 innings in five of their last six games as road underdogs against NL Central opponents.

Why the Cincinnati Reds will win

  • The underdogs have won three of the Reds’ last four games at PNC Park.
  • The Pirates have lost four of their last six games as favorites following a loss.
  • The Pirates have failed to cover the run line in seven of their last eight games as favorites against NL Central opponents.
  • The Reds have covered the run line in five of their last six games as road underdogs.

Pittsburgh Pirates Player Prop Facts

  • Andrew McCutchen has hit a home run in two of the Pirates’ last three games against opponents that held a winning record.
  • Andrew McCutchen has recorded at least one hit in each of his last 10 home appearances against opponents that held a winning record.
  • Oneil Cruz ranks 2nd in the league in Steals (34) this season.

Cincinnati Reds Player Prop Facts

  • Spencer Steer has hit a home run in three of the Reds’ last four Thursday games against NL opponents that held a losing record.
  • Brady Singer has recorded six or more strikeouts in each of his last four appearances with his team as a road underdog against NL Central opponents.
  • Spencer Steer has recorded a hit in each of the Reds’ last seven games at PNC Park.
  • Jose Trevino has recorded a Double in each of his last three road appearances against NL Central opponents.

Cincinnati Reds vs Pittsburgh Pirates Prediction

The Reds are playing the better ball, but I’m not excited to get behind Singer, who has a 5.73 ERA and .289 allowed batting average in 48.2 road innings. The Pirates aren’t winning games and are awful offensively, but Skenes is one of the best pitchers in baseball. In 62.2 home innings, Skenes has a 1.87 ERA and .180 allowed batting average. I’m not thrilled to get behind the Pirates, but there’s a clear pitching edge in this spot. Give me the home team.

Randy Chambers's Pick: Pittsburgh Pirates

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