Aug 9, 2025; Detroit, Michigan, USA;  Los Angeles Angels starting pitcher Yusei Kikuchi (16) throws a pitch against the Detroit Tigers in the first inning at Comerica Park. Mandatory Credit: Lon Horwedel-Imagn Images

Cincinnati Reds vs Los Angeles Angels Prediction 8/20/2025 Today’s MLB Picks

Pick details

Cincinnati (67-60) vs Los Angeles (60-66)

August 20, 2025 at 09:38 PM EDT

The Line: Betting Odds: Los Angeles -132 / Cincinnati +119 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a Reds vs Angels Prediction for this MLB game on Wednesday, August 20th at the Angel Stadium in the third game of this series, with the Reds having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 60-66 record this season and are sitting on the 4th place of the AL West. The Angels have a 33-32 home record and 71-52 in over/under They are coming off a 4-6 home defeat by the Reds, and are 1-4 in their last 5 games. Over is 9-2 in their last 11 games and are playing the Cubs and the Rangers next.

The Angels have a .233 batting average this season, .306 OBP and .408 Slugging percentage. LA’s pitching staff has a 4.70 ERA and 1.44 WHIP. Nolan Schanuel leads the Angels with 123 hits, and he is the team’s best hitter with a .269 batting average. Taylor Ward leads the team with 92 RBI, adding a team-high 29 home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 6-8 record, 3.52 ERA and 1.44 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 67-60 record this season and are sitting in the third place of the NL Central. The Reds have a 31-31 road record and are 46-74 in over/under. They are coming off a 6-4 road victory over the Angels, and have three consecutive wins. They are playing the Diamondbacks and the Dodgers next.

The Reds have a .248 batting average this season, .319 OBP and .393 slugging percentage. Cincinnati’s pitching staff has a 3.80 ERA and 1.24 WHIP. Elly De La Cruz leads the Reds with 135 hits, and in RBI, with 76, adding a team-high 19 home runs. Gavin Lux is the team’s best hitter with a .280 batting average.

Nick Martinez (R) is the projected starting pitcher for the Reds, and he has a 10-9 record, 4.73 ERA and 1.23 WHIP.

Why the Los Angeles Angels will win

  • The Angels have won six of their last seven night games against National League opponents following a home loss.
  • The Reds have lost three of their last four games against AL West opponents following a road win.
  • The favorites have covered the run line in each of the last five games between the Reds and Angels.
  • The Reds have failed to cover the run line in seven of their last nine night games against teams that held a losing record.
  • The Reds have trailed after 5 innings in four of their last five games as underdogs against American League opponents.
  • The Reds have lost the first inning in four of their last five games against AL West opponents that held a losing record.
  • The Reds have trailed after 3 innings in seven of their last eight games as road underdogs against American League opponents.

Why the Cincinnati Reds will win

  • The Reds have won each of their last 10 games against the Angels.
  • The Angels have lost each of their last 10 games against the Reds following a loss.
  • The Reds have covered the run line in each of their last 10 games against the Angels.
  • The Angels have failed to cover the run line in each of their last nine games against the Reds following a loss.
  • The Angels have lost the first inning in four of their last five night games.
  • The Angels have trailed after 3 innings in each of their last six Wednesday night games as favorites.
  • The Reds have led after 5 innings in seven of their last eight night games against the Angels.

Total Runs Facts

  • Five of the Angels’ last six games as favorites against National League opponents have gone OVER the total runs line.
  • Seven of the Reds’ last nine road games against American League opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last 10 games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Reds’ last 11 night games against AL West opponents.

Matchup/League Facts

  • The Angels rank 30th in the league for strikeouts against this season (1235).
  • The Angels rank 30th in the league for walks allowed this season (484).
  • The Reds rank 6th in the league for opponent batting average this season (.234).
  • The Reds rank 6th in the league for hits allowed this season (995).

Reds vs Angels Prediction

The Reds have won their last 10 meetings against the Angels, having won their last five visits in Los Angeles.

In this Reds vs Angels Prediction, the Reds are coming as -135 favorites. Kikuchi takes the mound for the Angels, and while he has been struggling lately, with back-to-back games with 4 earned runs, he has been better at home throughout the season, with a 2.40 home ERA. Martinez was torched in his last start, having given up 5 runs in just 2.2 innings pitched, and the Reds are terrible against left-handed pitching, so this looks like a nice bounce-back sport for the home team. Take the Los Angeles Angels to get the job done at home in this one.

Nikos Lagouretos's Pick: Los Angeles Angels -132

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