Cincinnati Reds vs Chicago White Sox Prediction 8/11/2026 Today’s MLB Picks

In this article, we will formulate a Reds vs White Sox Prediction for this MLB matchup on Tuesday, August 11th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 61-56 record this season and are sitting in the 1st place of the AL Central. They have a 36-22 home record and are coming off a 5-3 home win against the Guardians. They will face the Tigers and the Cubs next.

The Chicago White Sox have a .237 batting average this season, .317 OBP and .405 Slugging percentage. Chicago’s pitching staff has a 4.11 ERA and 1.31 WHIP. Chase Meidroth is the team’s best hitter with a .274 batting average. Colson Montgomery leads the team in RBI with 68, while Munetaka Murakami adds a team-high 26 home runs.

Sean Burke (R) is the projected starting pitcher for the White Sox, and he has a 7-6 record, 3.08 ERA and 1.12 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 56-61 record this season and are sitting in the 5th place of the NL Central. They have a 27-30 away record and are coming off a 1-7 road loss against the Nationals. They will face the Marlins and the Cardinals next.

The Cincinnati Reds have a .229 batting average this season, .309 OBP and .397 Slugging percentage. Cincinnati’s pitching staff has a 4.48 ERA and 1.41 WHIP. Elly De La Cruz is the team’s best hitter with a .271 batting average. Sal Stewart leads the team in RBI with 87, adding a team-high 25 home runs.

Nick Lodolo (L) is the projected starting pitcher for the Reds, and he has a 3-2 record, 4.60 ERA and 1.47 WHIP.

Cincinnati Reds @ the Chicago White Sox Betting Trends: August 11, 2026

• Probable Starting Pitcher: Sean Burke      Record this season: 7-6      ERA: 3.08
• Home Record: 2-4
• Last 5 against Reds: –

Why the Chicago White Sox will win

• The home team has won each of the Reds’ last seven games.
• The Reds have lost four of their last five road games.
• The Reds have failed to cover the run line in each of their last six games.
• The White Sox have covered the run line in eight of their last nine night games against National League opponents that held a losing record.
• The White Sox have led after 3 innings in five of their last six games as favorites against NL Central opponents.
• The Reds have trailed after 5 innings in each of their last four road night games.

• Probable Starting Pitcher: Nick Lodolo      Record this season: 3-2      ERA: 4.60
• Road Record: 1-0
• Last 5 against White Sox: 1-1

Why the Cincinnati Reds will win

• The White Sox have lost each of their last 10 home games against NL Central opponents that held a losing record.
• The Reds have won each of their last four games as underdogs against American League opponents following a loss.
• The White Sox have failed to cover the run line in 12 of their last 13 home games against NL Central opponents that held a losing record.
• The Reds have covered the run line in each of their last four games as underdogs against American League opponents following a loss.
• The White Sox have lost the first inning in three of their last four home games against NL Central opponents.
• The White Sox have trailed after 5 innings in nine of their last 11 home games against NL Central opponents that held a losing record.
• The White Sox have trailed after 3 innings in five of their last six games against National League opponents.

Total Runs Facts

• Each of the Reds’ last six games as road underdogs have gone UNDER the total runs line.
• Each of the White Sox’s last four games against NL Central opponents have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the White Sox’s last seven games against NL Central opponents.
• There has been no run scored during the first inning in four of the Reds’ last five games as road underdogs.

Chicago White Sox Player Prop Facts

• Colson Montgomery has hit a home run in three of the White Sox’s last four games against NL Central opponents.
• Sean Burke has recorded eight or more strikeouts in each of his last four appearances in night games against teams that held a losing record.
• Munetaka Murakami has recorded at least one hit in each of the White Sox’s last 10 home games.
• Colson Montgomery ranks T9th in the league in Home Runs (26) this season.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in each of his last two road appearances against AL opponents that held a winning record.
• Nick Lodolo has recorded five or more strikeouts in each of his five previous road appearances against AL opponents.
• Elly De La Cruz has recorded at least one hit in each of the Reds’ last 16 road games against AL Central opponents.

Matchup/League Facts

• The White Sox rank 25th in the league for hits this season (930).
• The White Sox rank 6th in the league for home runs this season (152).
• The Reds rank 30th in the league for hits this season (890).
• The Reds rank 30th in the league for batting average this season (.229).

Reds vs White Sox Prediction

The Reds are 4-2 in their last 6 meetings against the White Sox, having won their last three visits in Chicago.

In this Reds vs White Sox Prediction, the White Sox are coming as -155 home favorites. I like the White Sox in this one at home with the red-hot Sean Burke on the bump, who has given up two runs or less in each of his last nine starts. On the flip side, Lodolo has not played for a month now and the Reds bats are cold, averaging just 3.1 runs per game in their last 5. On top of that, the White Sox also have a better bullpen and I expect them to get the job done at home in this one.

Nikos Lagouretos's Pick: Chicago White Sox ML