Aug 19, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks outfielder Corbin Carroll loses his helmet as he runs the bases after hitting a triple in the fourth inning against the Cleveland Guardians at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

Cincinnati Reds vs Arizona Diamondbacks Prediction 8/23/2025 Today’s MLB Picks

Pick details

Cincinnati (67-62) vs Arizona (63-66)

August 23, 2025 at 08:10 PM EDT

The Line: Betting Odds: Arizona +115 — Over/Under: +9

(Get latest betting odds)

The Cincinnati Reds and the Arizona Diamondbacks meet Friday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Cincinnati Reds will send out Andrew Abbott for the start here and Abbott is 8-3 with a 2.28 ERA and 112 strikeouts this season. This will be Abbott’s second career start against the Diamondbacks. The Arizona Diamondbacks will start Nabil Crismatt here and Crismatt is 0-0 with a 1.80 ERA and 5 strikeouts this season. This will be Crismatt’s first career start against the Reds.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to rebound from a 6-5 loss at the hands of the Diamondbacks on Friday to sit at 67-62 this season. After this series, the Reds will head on the road for a series against the Los Angeles Dodgers.

Reds Lose Back-To-Back Games

Elly De La Cruz has 135 hits with 19 home runs, 76 RBIs, 25 doubles and 31 stolen bases while TJ Friedl has 121 hits with 18 doubles, 10 home runs and 40 RBIs with 11 stolen bases. Gavin Lux has added 100 hits with 21 doubles and 48 RBIs while Spencer Steer has 15 home runs and 59 RBIs and Matt McLain has added 11 homers, 40 RBIs and 16 stolen bases as well on the year. Jose Trevino’s also chipped in 19 doubles as well this season.

Why the Cincinnati Reds will win

  • The favorites have won each of the Reds’ last seven games.
  • The Diamondbacks have lost five of their last six night games against NL Central opponents following a home win.
  • The Diamondbacks have failed to cover the run line in each of their last seven night games against NL Central opponents following a home win.
  • The Reds have covered the run line in each of their last seven games against the Diamondbacks.

Cincinnati Reds Player Prop Facts

  • Miguel Andujar has recorded a Double in each of his last four appearances in night games against teams that held a losing record.
  • Miguel Andujar has recorded at least one hit in each of his last 10 appearances in night games.
  • Tyler Stephenson has hit at least one home run in three of his last five appearances in night games against NL West teams that held a losing record.
  • Elly De La Cruz ranks T8th in the league in Steals (31) this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their win over the Reds from Saturday to sit at 63-66 this season. After this series, the Diamondbacks will take to the road for a series against the Milwaukee Brewers.

Diamondbacks Win Three In A Row

Corbin Carroll has 113 hits with 27 home runs, 65 RBIs, 16 triples and 22 doubles this season. Carroll also has 17 stolen bases and Geraldo Perdomo has a team-high 22 stolen bases as well as 13 home runs and 81 RBIs with a team-high 134 hits this season. Ketel Marte’s added 23 home runs and 56 RBIs as well on the year and Lourdes Gurriel has 115 hits with 23 doubles, 17 home runs and 71 RBIs.

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won each of their last seven games as home underdogs against NL Central opponents.
  • The Reds have lost nine of their last 10 games as favorites against NL West opponents following a road loss.
  • The Reds have failed to cover the run line in each of their last 10 games as favorites against NL West opponents following a road loss.
  • The underdogs have covered the run line in each of the last nine games between the Reds and Diamondbacks.

Arizona Diamondbacks Player Prop Facts

  • Geraldo Perdomo has recorded at least one hit in each of the Diamondbacks’ last 10 home games against NL opponents.
  • Gabriel Moreno has hit a home run in three of his last four appearances in night games against teams that held a winning record.
  • Corbin Carroll ranks 5th amongst qualified players for Slugging Percentage (.556) this season.

Total Runs Facts

  • Each of the Reds’ last six games following an extra innings loss have gone UNDER the total runs line.
  • Five of the Diamondbacks’ last six home games against NL Central opponents have gone OVER the total runs line.

Cincinnati Reds vs. Arizona Diamondbacks Prediction

I’m going to take a stab at Arizona here. Normally I’m big on backing the Reds when Andrew Abbott takes the mound, but the thing is that Abbott hasn’t necessarily gotten the best support lately from his offense and the Diamondbacks have actually been surprisingly solid against left-handed pitching in the last couple of weeks. I will have my concern about the Diamondbakcs’ bullpen always, but I still think that the Diamondbacks can get the job done in this one. Give me the D-Backs here.

Chris Ruffolo's Pick: Arizona +115

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