Aug 13, 2025; Kansas City, Missouri, USA; Kansas City Royals first baseman Vinnie Pasquantino (9) hits a home run during the fourth inning against the Washington Nationals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

Chicago White Sox vs Kansas City Royals Prediction 8/15/2025 Today’s MLB Picks

Pick details

Chicago (44-77) vs Kansas City (60-61)

August 15, 2025 at 08:10 PM EDT

The Line: Betting Odds: Kansas City -185 — Over/Under: +9

(Get latest betting odds)

The Chicago White Sox and the Kansas City Royals meet Monday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs. Kansas City Royals prediction.

Starting Pitching Matchup

The Chicago White Sox will start Aaron Civale here and Civale is 3-7 with a 4.91 ERA and 62 strikeouts this season. In his last five starts against the Royals, Civale is 4-0 with a 1.97 ERA and 33 strikeouts. Noah Cameron will get the nod for the Royals here and is 6-5 with a 2.52 ERA and 76 strikeouts this season. This will be Cameron’s first career start against the White Sox.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to rebound from a 1-0 loss at the hands of the Detroit Tigers last time out to sit at 44-77 this season. After this series, the White Sox will head on the road for a series against the Atlanta Braves.

White Sox Drop 8 Of Their Last 10

Lenyn Sosa has 102 hits including 16 doubles and 48 RBIs. Andrew Benintendi has 72 hits including 13 doubles, 14 home runs, 45 RBIs and a .223 batting average while Miguel Vargas has 90 hits, 25 doubles, 13 home runs and 44 RBIs. Brooks Baldwin has also added 26 RBIs while Luis Robert Jr. has a team-high 31 stolen bases along with 47 RBIs so far this season. Chase Meidroth has added 78 hits with 11 stolen bases as well as 12 doubles this season.

Why the Chicago White Sox will win

  • The White Sox have won each of their last seven night games against teams that held a losing record.
  • The Royals have lost eight of their last 10 games as home favorites against American League opponents.
  • The White Sox have covered the run line each of their last six night games against teams that held a losing record.
  • The Royals have failed to cover the run line in seven of their last eight night games against AL Central opponents.

Chicago White Sox Player Prop Facts

  • Aaron Civale has recorded a win in four of his last five appearances against the Royals.
  • Aaron Civale has recorded five or more strikeouts in each of his last six appearances against the Royals.
  • Luis Robert has recorded at least one hit in each of his last 12 appearances against opponents that held a losing record.
  • Michael A. Taylor has hit a home run in each of the White Sox’s last two games as road underdogs.
  • Michael A. Taylor has recorded a Double in four of his last five appearances after not playing the previous day.
  • Luis Robert ranks T5th in the league in Steals (31) this season.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to rebound from an 8-7 loss at the hands of the Washington Nationals last time out to sit at 60-61 this season. After this series, the Royals will square off against the Texas Rangers at home.

Royals Looking To Rebound

Bobby Witt Jr. has 135 hits with 37 doubles and 30 stolen bases along with 4 triples, 17 home runs and 67 RBIs while Vinnie Pasquantino has 120 hits with 20 doubles, a triple, 22 home runs and 80 RBIs. Maikel Garcia’s added 133 hits with 31 doubles, 5 triples, 11 home runs and 51 RBIs and 22 stolen bases and Salvador Perez also has 21 home runs and 68 RBIs but also has 98 strikeouts so far this season.

Why the Kansas City Royals will win

  • The White Sox have lost each of their last 11 games at Kauffman Stadium.
  • The Royals have won each of their last 11 night games against the White Sox following a loss.
  • The Royals have covered the run line in each of their last seven night games against the White Sox following a loss.
  • The White Sox have failed to cover the run line in four of their last five night games following a loss.

Kansas City Royals Player Prop Facts

  • Vinnie Pasquantino has hit a home run in three of the Royals’ last four games as favorites.
  • Maikel Garcia has recorded at least one hit in each of his last 10 appearances with the Royals as favorites against AL Central opponents.
  • Bobby Witt Jr. ranks 6th in the league in Hits (135) this season.

Total Runs Facts

  • Nine of the last 10 games between the White Sox and Royals at Kauffman Stadium have gone UNDER the total runs line.
  • Four of the White Sox’s last five road games against AL Central opponents have gone UNDER the total runs line.

Chicago White Sox vs. Kansas City Royals Prediction

I’m going to take a shot on Chicago here. I just think this price is a bit too rich for my blood with the Royals who have still been a relatively inconsistent offense for much of the season. The White Sox haven’t been much better, but Civale has really strong numbers against the Royals in his career even if the recent numbers overall haven’t been great. I’ll side with the White Sox and the hefty plus money in this one.

Chris Ruffolo's Pick: Chicago +155

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