Chicago White Sox vs Baltimore Orioles Prediction 5/31/25 MLB Picks

The Chicago White Sox and Baltimore Orioles meet Saturday in MLB action at Oriole Park at Camden Yards. Here’s a Chicago White Sox vs Baltimore Orioles Prediction. This article will include a Chicago White Sox vs Baltimore Orioles Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 18-39 on the year and play the Tigers, Royals, and Astros next. The Chicago White Sox are batting .221 on the season, have a .293 OBP, and a .343 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 54 hits and 17 RBI, while Miguel Vargas and Andrew Vaughn have combined for 84 hits and 45 RBI. 

Davis Martin gets the ball for the Chicago White Sox, and he is 2-5 with a 3.45 ERA and 38 strikeouts this season. This will be Martin’s first career game against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 20-36 on the year and play the Mariners, Athletics, and Tigers next. The Baltimore Orioles are batting .237 on the season, have a .303 OBP, and a .384 slugging percentage. The Baltimore Orioles pitching staff has a 5.41 ERA and a 1.47 WHIP. Ryan O’Hearn leads the Baltimore Orioles with 55 hits and 21 RBI, while Gunnar Henderson and Jackson Holliday have combined for 101 hits and 39 RBI.

Dean Kremer gets the ball for the Baltimore Orioles, and he is 4-5 with a 5.02 ERA and 44 strikeouts this season. Kremer is 1-0 with a 0.77 ERA and 9 strikeouts in his career against the Chicago White Sox.

Why the Baltimore Orioles will win

• The White Sox have lost 12 of their last 13 road games against American League opponents that held a losing record.
• The Orioles have won seven of their last eight games against the White Sox.
• The White Sox have failed to cover the run line in six of their last seven games against the Orioles following a loss.
• The Orioles have covered the run line in five of their last six games as favorites against the White Sox following a win.
• The Orioles have led after 5 innings in four of their last five day games against American League opponents that held a losing record.
• The Orioles have led after 3 innings in three of their last four day games against AL Central opponents that held a losing record.

Why the Chicago White Sox will win

• The Orioles have lost each of their last eight day games against AL Central opponents.
• The White Sox have won three of their last four games as underdogs against AL East opponents following a road loss.
• The Orioles have failed to cover the run line in each of their last nine games as home favorites after playing the previous day.
• The White Sox have covered the run line in each of their last six games against American League opponents.

Baltimore Orioles Player Prop Facts

• Dean Kremer has recorded a win in three of his last four appearances with the Orioles as home favorites against AL opponents.
• Gunnar Henderson has hit a home run in five of the Orioles’ last seven home games against AL Central opponents that held a losing record.
• Ryan O’Hearn has recorded at least one Single in each of the Orioles’ last six day games.
• Gunnar Henderson has scored at least one run in each of the Orioles’ last seven games against the White Sox at Oriole Park at Camden Yards.
• Dean Kremer has recorded five or more strikeouts in each of his last five home appearances against AL opponents that held a losing record.
• Ramon Urias has recorded at least one RBI in four of the Orioles’ last five games against AL opponents.
• Ryan Mountcastle has recorded at least one Double in three of his last four home appearances after playing the previous day.
• Ramon Urias has recorded at least one hit in each of his last 10 appearances after playing the previous day.

Chicago White Sox vs Baltimore Orioles Prediction

I’m not excited to back either of these teams, as we’ve faded the White Sox and Orioles a lot this season. However, the Orioles are having their best week of the season and have to view this as a chance to chip away in the standings. Kremer is having a strong month, where he’s allowed 29 hits and 10 runs in his last 30.1 innings. Kremer has also been great through 18 home innings, posting a 2.50 ERA and .206 allowed batting average. The Orioles should win this game. Of course, I’ll lay the RL to shave down the juice.