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Chicago Cubs vs Washington Nationals Prediction 6/3/25 MLB Picks

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Washington Nationals (28-31) vs Chicago Cubs (37-22)

June 3, 2025 at 06:45 PM EDT

The Line: Betting Odds: Washington Nationals +130 / Chicago Cubs -155 — Over/Under: 9

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The Chicago Cubs are visiting the Washington Nationals on Tuesday, June 3rd at the Nationals Park in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s Chicago Cubs vs Washington Nationals Prediction. We will examine:

The Washington Nationals recent form and player performance

The Chicago Cubs recent form and player performance

Recent betting trends and streaks involving the Washington Nationals

Recent betting trends and streaks involving the Chicago Cubs

Recent betting trends in games played between the Chicago Cubs vs Washington Nationals

A summary that ties it all together and produces a favorable betting outcome for Chicago Cubs vs Athletics game

Washington Nationals Preview

The Washington Nationals have a 28-31 record this season and are sitting on the third place of the NL East. The Nationals have a 13-14 home record and are 29-28 in over/under They are coming off a 1-3 road defeat by the Diamondbacks, which ended their previous four-game winning streak. Over is 5-1 in their last 6 games, and are playing the Mets and the Rangers next.

The Nationals have a .244 batting average this season, .313 OBP and .396 Slugging percentage. Washington’s pitching staff has a 5.02 ERA and 1.39 WHIP. James Wood leads the Nationals with 64 hits, 44 RBI and a team-high 16 home runs, while being the team’s best hitter with a .286 batting average.

Trevor Williams (R) will take the mound for the Nationals, and he has a 3-5 record, 5.69 ERA and 1.45 WHIP. He has been weaker at home with a 6.48 ERA across five home starts, but he is coming off a shutout start against the Mariners in 6 innings of work. Trevor Williams has a 4-8 record with an ERA of 4.55, 68 strikeouts and 1 save in 18 appearances against the Cubs in his career.

Chicago Cubs Preview

The Chicago Cubs have a 37-22 record this season and are sitting on the first place of the NL Central. The Cubs have a 17-11 road record and are 32-21 in over/under. They are coming off a 7-3 home victory over the Reds, and are playing the Tigers and the Phillies next.

The Cubs have a .261 batting average this season, .336 OBP and .447 Slugging percentage. Chicago’s pitching staff has a 3.84 ERA and 1.25 WHIP. Nico Hoerner leads the Cubs with 65 hits and he is the team’s best hitter with a .301 batting average. Seiya Suzuki leads the team in RBI, with 52.

Cade Horton (R) will take the mound for the Cubs, and he has a 2-0 record, 3.98 ERA and 1.23 WHIP. He has been slightly better on the road, with a 3.86 ERA in his two road games, and this will be his first career start against the Nationals.

Why the Washington Nationals will win

  • The underdogs have won five of the Nationals’ last six games at Nationals Park.
  • The Cubs have lost three of their last four games as road favorites against NL East opponents following a home win.
  • The Cubs have failed to cover the run line in each of their last eight night games against National League opponents following a home win.
  • The underdogs have covered the run line in each of the Nationals’ last six games at Nationals Park.
  • The Cubs have trailed after 5 innings in each of their last three road games against National League opponents that held a losing record.
  • The Cubs have lost the first inning in each of their last three road games against National League opponents that held a losing record.
  • The Cubs have trailed after 3 innings in each of their last three road games.

Why the Chicago Cubs will win

  • The Nationals have lost each of their last six home games against NL Central opponents.
  • The Cubs have won eight of their last nine games against the Nationals.
  • The Nationals have failed to cover the run line in each of their last five home games against NL Central opponents.
  • The road team has covered the run line in four of the Nationals’ last five games.
  • The Nationals have trailed after 5 innings in each of their last six home games against NL Central opponents.
  • The Nationals have trailed after 3 innings in each of their last five games as underdogs against NL Central opponents.

Total Runs Facts

  • Each of the Nationals’ last six night games as underdogs have gone OVER the total runs line.
  • Five of the Cubs’ last six road games have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cubs’ last six road games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last six night games between the Cubs and Nationals.

Matchup/League Facts

  • The Nationals rank 26th in the league for ERA this season (5.02).
  • The Nationals rank T6th in the league for triples this season (10).
  • The Cubs rank T1st in the league for RBIs this season (333).
  • The Cubs rank 2nd in the league for runs scored this season (341).

Chicago Cubs vs Washington Nationals Prediction

The Cubs are 8-2 in their last 10 overall meetings against the Nationals, and have won their last three visits in Washington. Under is 3-0 in their last 3 meetings.

In this Chicago Cubs vs Washington Nationals Prediction, the Cubs are coming as -143 road favorites. The Cubs are rightfully favored, as they have a better overall record this season, and have been very good on the road, while the Nationals are mediocre at home. Both teams have been in very good form lately, but the Nationals finally cooled off with a 1-3 loss to the Dbacks, after having scored 9+ runs in four straight games. The Cubs have the better bullpen and superior offense, as they are second in the MLB in runs scored. Trevor Williams has been terrible for the Nationals this season, so this game has Cubs written all over it. Take the Chicago Cubs on the moneyline on the road.

Nikos Lagouretos's Pick: Chicago Cubs ML

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