Chicago Cubs vs Boston Red Sox Prediction 07/20/2025 Picks

The Boston Red Sox and the Chicago Cubs meet Sunday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Chicago Cubs prediction.

Starting Pitching Matchup

The Boston Red Sox will start Garrett Crochet here, and Crochet is 10-4 with a 2.23 ERA and 160 strikeouts this season. This will be Crochet’s second career start against the Cubs. Cade Horton will get the nod for the Cubs here and is 3-3 with a 4.45 ERA and 43 strikeouts this season. This will be Horton’s first career start against the Red Sox.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from their 6-0 loss at the hands of the Cubs on Saturday to sit at 53-47 on the year. After this series, the Red Sox will head on the road for an interleague series against the Phillies.

Red Sox Looking To Avoid Sweep

Alex Bregman has 61 hits, including 18 doubles, along with 11 home runs and 35 RBIs this season. Trevor Story added 93 hits with 15 home runs, 58 RBIs, and 16 stolen bases, while Jarren Duran has 103 hits with 25 doubles, 10 triples, 8 home runs, 50 RBIs, and a team-high 16 stolen bases. Kristian Campbell added 51 hits with 10 doubles, 6 homers, and 21 RBIs while Wilyer Abreu has 18 home runs with 52 RBIs and 5 stolen bases and Ceddanne Rafaela has 14 homers, 21 doubles, 2 triples, 48 RBIs, and 13 stolen bases this season.

Why the Boston Red Sox will win

The favorites have won each of the Red Sox’s last 12 games.
The Cubs have lost four of their last five day games against AL East opponents following a home win.
The Cubs have failed to cover the run line in each of their last six day games against AL East opponents following a home win.
The Red Sox have covered the run line in each of their last six games as favorites against National League opponents.

Boston Red Sox Player Prop Facts

Triston Casas has hit a home run in four of his last five road appearances against NL Central opponents.
Ceddanne Rafaela has recorded at least one Double in five of his last six appearances with the Red Sox as favorites against NL opponents.
Ceddanne Rafaela has recorded at least one hit in each of his last 12 appearances.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to build on their win over Boston from Saturday to sit at 59-39 on the year. After this series, the Cubs will square off in an interleague series with the Kansas City Royals at home.

Cubs Win Four In A Row

Ian Happ has 79 hits with 15 doubles, 12 home runs and 46 RBIs. Kyle Tucker has 100 hits including 19 doubles, 4 triples, 17 home runs and 56 RBIs while Seiya Suzuki also has 97 hits with 24 doubles and 25 home runs and 77 RBIs of his own. Pete Crow-Armstrong also has contributed 99 hits, 21 doubles, 4 triples, 25 home runs and 71 RBIs as well this season. Dansby Swanson has added 16 home runs and 47 RBIs, while also having 105 strikeouts and Suzuki has a team-high 109 strikeouts so far this season. Crow-Armstrong also has a team-high 27 stolen bases while Nico Hoerner has 16 stolen bases this season. Tucker’s also added 22 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 19 home runs and 59 RBIs this season.

Why the Chicago Cubs will win

The home team has won each of the Red Sox’s last nine games.
The Red Sox have lost 12 of their last 13 road games against National League opponents that held a winning record.
The Red Sox have failed to cover the run line in each of their last six games following a road loss.
The Cubs have covered the run line each of their last four games against teams that held a winning record.

Chicago Cubs Player Prop Facts

Kyle Tucker has hit a home run in three of the Cubs’ last four games as home underdogs.
Seiya Suzuki has recorded a Double in three of the Cubs’ last four day games against opponents that held a winning record.
Justin Turner has recorded at least one hit in each of his last eight appearances with his team as a home underdog against AL East opponents.
Pete Crow-Armstrong ranks 4th in the league in Steals (28) this season.

Total Runs Facts

Each of the Cubs’ last eight day games against AL East opponents have gone UNDER the total runs line.
Each of the Red Sox’s last seven games as favorites against National League opponents have gone OVER the total runs line.

Boston Red Sox vs. Chicago Cubs Prediction

I’m on the Red Sox here. I get that the Cubs have been the better team so far in this series and the Red Sox just haven’t been able to get out of the blocks, but Garrett Crochet has been a strong option for the Red Sox this season and has assumed the role of stopper for this team. The Cubs haven’t been as strong against left-handed pitching as they were to start the season, and I think Crochet can do enough here to help Boston salvage a win to close out the series. Give me Boston here.