Aug 12, 2025; Cincinnati, Ohio, USA; Cincinnati Reds shortstop Elly De La Cruz (44) high fives second baseman Matt McLain (9) and first baseman Spencer Steer (7) after the victory over the Philadelphia Phillies at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Cardinals vs Reds Prediction 8/31/2025 Today’s MLB Picks

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Reds (68-68) vs Cardinals (68-69)

August 31, 2025 at 12:10 PM EDT

The Line: Betting Odds: Cincinnati -133 — Over/Under: 8.5

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In this article we will formulate a Cardinals vs Reds prediction for this MLB game on Sunday, August 31st at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 68-69 this year after they won the first two games in this series by scores of 7-5 and 4-2. In their game two win, St. Louis had their lead cut to 3-2 in the seventh inning, but they added an insurance run in the eighth to seal the victory. The Cardinals recorded seven hits in the game and they were led by Church, who went 1-3 with two RBIs in the win. St. Louis started McGreevy, who allowed five hits and one earned run over 6.0 innings for the win, while Leahy picked up the save. 

Prior to this series, the Cardinals split four games with the Pirates and lost two out of three against the Rays. St. Louis has won three games in a row and they are fourth in the NL Central standings. The St. Louis pitching staff has a 4.27 ERA with a 1.31 WHIP and a .257 opponent batting average, while their offense has scored 599 runs with a .247 batting average and a .316 on base percentage this season. Wilson Contreras has led St. Louis with 20 home runs, 74 RBIs, and four stolen bases, while Alec Burleson (IL) has added 16 home runs and 60 RBIs this year. The projected starting pitcher for St. Louis is Andre Pallante, who is 6-12 with a 5.44 ERA and a 1.42 WHIP over 139.0 innings pitched this year. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 68-68 this season after they lost game two by a score of 4-2 on Saturday night. Cincinnati led 1-0 in the first inning, but only scored once in the final eight innings for the loss. The Reds recorded eight hits in the game and they were led by McLain and Lux, who both had one RBI in the loss. Cincinnati started Abbott, who allowed three hits and two earned runs over 5.0 innings for the loss, while Phillips and Maxwell both allowed one earned run in relief. 

Prior to this series, the Reds lost all three against the Dodgers and two out of three against the Diamondbacks. Cincinnati has lost eight of their last nine games and they are currently third in the NL Central standings. The Cincinnati pitching staff has a 3.84 ERA with a 1.24 WHIP and a .235 opponent batting average, while their offense has scored 604 runs with a .246 batting average and a .317 on base percentage this season. Elly De La Cruz has led Cincinnati with 19 home runs and 77 RBIs, while Spencer Steer has added 17 home runs and 63 RBIs this year. The projected starting pitcher for Cincinnati is Brady Singer, who is 11-9 with a 4.06 ERA and a 1.27 WHIP over 137.1 innings pitched this season. 

Why the Reds will beat the Cardinals 

The Reds have won each of their last seven day games at Great American Ball Park following a loss.
The Cardinals have lost 10 of their last 11 day games against NL Central opponents following a road win.
The Cardinals have failed to cover the run line in five of their last six day games against the Reds at Great American Ball Park following a win.
The Reds have covered the run line in four of their last five day games against the Cardinals following a loss.
The Reds have won the first inning in each of their last three games as favorites against the Cardinals.

Total Runs Facts

Thirteen of the Reds’ last 14 day games after playing the previous day have gone UNDER the total runs line.
Four of the Cardinals’ last five road games against NL Central opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last five road games against NL Central opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four games between the Cardinals and Reds.

Cincinnati Reds Player Prop Facts

Spencer Steer has hit a home run in each of the Reds’ last two day games against NL opponents that held a losing record.
Brady Singer has recorded a win in each of his last three appearances at Great American Ball Park.
Brady Singer has recorded six or more strikeouts in each of his last four appearances at Great American Ball Park.
Elly De La Cruz has recorded at least one hit in each of the Reds’ last seven home games.
Elly De La Cruz ranks T10th in the league in Hits (145) this season.

St. Louis Cardinals Player Prop Facts

Willson Contreras has hit a home run in four of the Cardinals’ last six road games.
Nolan Arenado has recorded at least one hit in 14 of his last 16 appearances against the Reds.

Matchup/League Facts

The Reds rank 7th in the league for hits allowed this season (1066).
The Reds rank T23rd in the league for home runs this season (134).
The Cardinals rank 4th in the league for walks allowed this season (382).
The Cardinals rank 26th in the league for home runs this season (131).

Cardinals vs Reds Prediction 

St. Louis has won the first two games in this series and they are looking to complete the series sweep and pass the Reds in the division with a win here. The Cardinals are 31-37 on the road this year, while the Reds are 36-31 at home. Cincinnati continues to really struggle over the last two weeks and they are starting Singer, who has allowed one earned run or fewer in four of his last five starts. The Cardinals are going with Pallante, who has allowed 7, 5, 4, and 6 earned runs in his last four outings. Take the Reds to get the win here.

David Racey's Pick: Reds ML

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