Brewers vs Pirates Prediction 9/5/2025 Today’s MLB Picks

In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Friday, September 5th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 86-55 this season after they lost two out of three against the Phillies by scores of 8-10, 6-3, and 0-2. In their game three loss, Milwaukee generated a decent number of baserunners, but they couldn’t find any runs in the shutout loss. The Brewers recorded seven hits in the game and they were led by Vaughn, who went 3-4 in the game. Milwaukee started Peralta, who allowed two hits and zero earned runs over 5.0 innings, while Myers picked up the loss in relief. 

Prior to that series, the Brewers won two out of three against the Blue Jays and split four games with the Diamondbacks. Milwaukee has lost three of their last four games and they are leading the NL Central standings. The Milwaukee pitching staff has a 3.63 ERA with a 1.24 WHIP and a .232 opponent batting average, while the offense has scored 717 runs with a .259 batting average and a .332 on base percentage this season. Christian Yelich has led Milwaukee with 27 home runs and 92 RBIs, while William Contreras has added 17 home runs and 69 RBIs this year. The projected starting pitcher for Milwaukee is Quinn Priester, who is 11-2 with a 3.28 ERA and a 1.24 WHIP over 134.1 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 64-77 this year after they won all three games against the Dodgers by scores of 9-7, 3-0, and 5-3. In their game three win, Pittsburgh led 5-0 in the fifth inning, but barely hung on in the ninth for the victory. The Pirates recorded nine hits in the game and they were led by Yorke, who went 1-3 with two RBIs in the win. Pittsburgh started Skenes, who allowed two hits and zero earned runs over 6.0 innings for the win, while Moretta allowed three earned runs in relief. 

Prior to that series, the Pirates won two out of three against the Red Sox and split four games with the Cardinals. Pittsburgh has won five of their last six games and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.87 ERA with a 1.22 WHIP and a .237 opponent batting average, while their offense has scored 517 runs with a .234 batting average and a .308 on base percentage this season. Oneil Cruz has led Pittsburgh with 19 home runs and 54 RBIs, while Bryan Reynolds has added 15 home runs and 70 RBIs this year. The projected starting pitcher for Pittsburgh is Johan Oviedo, who is 2-0 with a 3.60 ERA and a 1.20 WHIP over 15.0 innings pitched this year. 

Why the Pirates will beat the Brewers

The Brewers have lost each of their last five games as favorites after playing the previous day.
The Pirates have won each of their last seven home games.
The Pirates have covered the run line in each of their last eight night games against National League opponents.
The Brewers have failed to cover the run line in 12 of their last 13 games as favorites after playing the previous day.
The Brewers have trailed after 3 innings in three of their last four road games against NL Central opponents.
The Brewers have trailed after 5 innings in three of their last four games against NL Central opponents.

Why the Brewers will beat the Pirates

The Brewers have won each of their last seven road games against teams that held a losing record.
The Pirates have lost five of their last six home games against the Brewers following a win.
The Brewers have covered the run line each of their last seven road games against National League opponents that held a losing record.

Total Runs Facts

Five of the Brewers’ last six games as road favorites have gone OVER the total runs line.
Three of the last four games between the Brewers and Pirates at PNC Park have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Pirates’ last five games as home underdogs.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Brewers’ last five night games at PNC Park.

Pittsburgh Pirates Player Prop Facts

Oneil Cruz has hit at least one home run in two of the Pirates’ last three games against the Brewers at PNC Park.
Johan Oviedo has recorded five or more strikeouts in six of his last seven appearances.
Bryan Reynolds has recorded at least one hit in each of his last 10 appearances against the Brewers after playing the previous day.
Joey Bart has recorded a Double in three of his last four appearances against NL opponents that held a winning record.

Milwaukee Brewers Player Prop Facts

William Contreras has hit a home run in each of the Brewers’ last two night games against opponents that held a losing record.
Andrew Vaughn has recorded at least one hit in each of his last 14 appearances in night games against NL Central teams that held a losing record.
Danny Jansen has recorded a Double in four of his last five appearances with his team as a road favorite against NL Central opponents.

Brewers vs Pirates Prediction

These two teams come into this series on opposite sides of the NL Central standings, but Pittsburgh is one of the hottest teams in the MLB right now. The Pirates are 42-30 at home this year, while the Brewers are 40-29 on the road. Pittsburgh is coming off of a sweep of the Dodgers and they are starting Oviedo, who has allowed two earned runs or fewer in three straight starts. Milwaukee is going with Priester, who has allowed two earned runs or fewer in four of his last five. I think we could see a lower scoring game with these two pitchers, so I like the under here.