Boston Red Sox vs San Diego Padres Prediction 8/8/2025 Today’s MLB Picks

The Boston Red Sox and San Diego Padres meet Friday in MLB action at Petco Park. Here’s a Boston Red Sox vs San Diego Padres Prediction. This article will include a Boston Red Sox vs San Diego Padres Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 64-52 on the year and play the Astros, Marlins, and Orioles next. The Boston Red Sox are batting .254 on the season, have a .323 OBP, and a .430 slugging percentage. The Boston Red Sox pitching staff has a 3.72 ERA and a 1.30 WHIP. Jarren Duran leads the Boston Red Sox with 121 hits and 64 RBI, while Trevor Story and Ceddanne Rafaela have combined for 213 hits and 124 RBI. 

Walker Buehler gets the ball for the Boston Red Sox, and he is 6-6 with a 5.74 ERA and 71 strikeouts this season. Buehler is 6-1 with a 1.80 ERA and 79 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 64-51 on the year and play the Giants, Dodgers, and Giants next. The San Diego Padres are batting .251 on the season, have a .320 OBP, and a .382 slugging percentage. The San Diego Padres pitching staff has a 3.58 ERA and a 1.21 WHIP. Manny Machado leads the San Diego Padres with 133 hits and 72 RBI while Luis Arraez and Fernando Tatis Jr. have combined for 240 hits and 87 RBI.

Nick Pivetta gets the ball for the San Diego Padres, and he is 11-3 with a 2.73 ERA and 136 strikeouts this season. Pivetta is 0-0 with a 0.69 ERA and 15 strikeouts in his career against the Boston Red Sox.

Why the San Diego Padres will win

• The Padres have won five of their last six games at Petco Park.
• The Red Sox have lost 14 of their last 17 road games against National League opponents that held a winning record.
• The Padres have covered the run line in five of their last six games at Petco Park against teams that held a winning record.
• The Red Sox have failed to cover the run line in four of their last five games as road underdogs following a loss.
• The Padres have led after 3 innings in eight of their last 10 games at Petco Park against opponents that held a winning record.
• The Padres have led after 5 innings in four of their last five games against opponents that held a winning record.

Why the Boston Red Sox will win

• The Red Sox have won each of their last six games following a home loss.
• The Padres have lost four of their last five games as home favorites against AL East opponents.
• The Red Sox have covered the run line in nine of their last 10 games as road underdogs against National League opponents following a home loss.
• The Padres have failed to cover the run line in nine of their last 10 home games against AL East opponents following a win.
• The Padres have trailed after 3 innings in each of their last three games as home favorites against AL East opponents.
• The Red Sox have led after 5 innings in six of their last seven night games against the Padres.

San Diego Padres Player Prop Facts

• Xander Bogaerts has hit a home run in each of the Padres’ last two games.
• Nick Pivetta has recorded seven or more strikeouts in three of his last four appearances at Petco Park.
• Jackson Merrill has recorded at least one hit in each of his last nine appearances against AL East opponents that held a winning record.
• Nick Pivetta ranks T4th in the league for Wins (11) this season.

Boston Red Sox Player Prop Facts

• Trevor Story has recorded at least one hit in each of the Red Sox’s last eight games.
• Trevor Story has recorded a Double in three of the Red Sox’s last four night games against opponents that held a winning record.
• Triston Casas has hit a home run in each of his last two appearances in night games against teams that held a winning record.

Boston Red Sox vs San Diego Padres Prediction

The Red Sox and Padres are on a heater right now so you can make a case for either side. The difference is Buehler has a 5.74 ERA and 1.60 WHIP on the season, and he has a 7.44 ERA and .328 allowed batting average in 42.1 road innings. Pivetta has a 2.73 ERA and 0.94 WHIP on the season, and he’s allowed five earned runs in his last 37.2 innings. In 72.1 home innings, Pivetta has a 1.99 ERA and .173 allowed batting average. Home field and a clear edge on the mound. Give me the Padres.