Boston Red Sox vs Houston Astros Prediction 8/13/2025 Today’s MLB Picks

In this article, we will formulate a Boston Red Sox vs Houston Astros Prediction for this MLB game on Wednesday, August 13th at the Daikin Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have a 67-53 record this season and are sitting on the second place of the AL West. The Astros have a 36-25 home record and 54-60 in over/under. They are coming off a 1-14 home defeat by the Red Sox, that ended their previous two-game winning streak. They are 6-1-1 to the over in their last 8 games and are playing the Orioles and the Tigers next.

The Astros have a .259 batting average this season, .323 OBP and .408 slugging percentage. Houston’s pitching staff has a 3.79 ERA and 1.20 WHIP. Jose Altuve leads the Astros with 127 hits, adding a team-high 21 home runs. Jeremy Pena is the team’s best hitter with a .318 batting average, while Christian Walker leads the team in RBI with 65.

Hunter Brown (R) is the projected starter for the Astros, and he has a 9-5 record, 2.51 ERA and 0.98 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 66-55 record this season and are sitting on the second place of the AL East behind the New York Yankees. The Red Sox have a 27-33 road record and are 60-58 in over/under. They are coming off a 14-1 road victory over the Astros, which ended their previous three-game losing streak. They are 11-2 to the over in their last 13 games and are playing the Marlins and the Orioles next.

The Red Sox have a .254 batting average this season, .325 OBP and .431 slugging percentage. Boston’s pitching staff has a 3.74 ERA and 1.30 WHIP. Jarren Duran leads the Red Sox with 126 hits, and he is the team’s best hitter, with a .265 batting average. Trevor Story leads the team in RBI, with 75, while Wilyer Abreu adds a team-high 21 home runs.

Walker Buehler (R) is the projected starting pitcher for the Red Sox, and he has a 7-6 record, 5.40 ERA and 1.56 WHIP.

Why the Houston Astros will win

• The Astros have won each of their last seven night games against AL East opponents following a loss.
• The Red Sox have lost four of their last five road games following a win.
• The Astros have covered the run line in six of their last seven night games against AL East opponents following a loss.
• The Red Sox have failed to cover the run line in four of their last five night games against AL West opponents following a road win.
• The Astros have led after 5 innings in seven of their last eight night games.
• The Astros have led after 3 innings in eight of their last 10 night games against the Red Sox at Daikin Park.

Why the Boston Red Sox will win

• The Astros have lost each of their last eight games as favorites against American League opponents.
• The Red Sox have won each of their last four games as underdogs against American League opponents.
• The Astros have failed to cover the run line in each of their last 16 games as favorites against American League opponents.
• The Red Sox have covered the run line in each of their last seven road games following a road win.
• The Astros have lost the first inning in four of their last five home games against American League opponents.
• The Astros have trailed after 5 innings in eight of their last nine games as home favorites against American League opponents.
• The Astros have trailed after 3 innings in eight of their last nine games as home favorites against American League opponents.

Total Runs Facts

• Each of the Red Sox’s last eight games have gone OVER the total runs line.
• Eight of the last nine games between the Red Sox and Astros at Daikin Park have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Red Sox’s last 11 games at Daikin Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the last eight night games between the Red Sox and Astros at Daikin Park.

Matchup/League Facts

• The Astros rank 1st in the league for strikeouts this season (1138).
• The Astros rank 2nd in the league for batting average this season (.259).
• The Red Sox rank 1st in the league for doubles this season (249).
• The Red Sox rank 2nd in the league for runs scored this season (613).

Boston Red Sox vs Houston Astros Prediction

The Red Sox are 6-1 in their last 7 meetings against the Astros, and are 4-1 this season in their 5 meetings this season. The Red Sox are 3-2 in their last 5 meetings in Houston and over is 7-4 in their last 11 meetings.

In this Boston Red Sox vs Houston Astros Prediction, the Astros are coming as -175 home favorites. The Astros are putting their ace on the mound in Hunter Brown, who has been excellent this season, and has been better at home with a 2.37 home ERA. His previous start against the Red Sox this season was a quality start with just one earned run. On the flip side. Buehler has been struggling for the Red Sox, and has been weaker on the road, with a 6.52 road ERA. The Astros are fighting with the Mariners for the top seed in the AL West, and they need every win they can get. They got a huge pitching advantage in this game, so I expect them to be in the lead as long as those two pitchers are on the mound. Take the Houston Astros on the runline in the first 5 innings.