Boston Red Sox vs Houston Astros Prediction 8/12/2025 Today’s MLB Picks

The Boston Red Sox and Houston Astros meet Tuesday in MLB action at Daikin Park. Here’s a Boston Red Sox vs Houston Astros Prediction. This article will include a Boston Red Sox vs Houston Astros Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 65-55 on the year and play the Marlins, Orioles, and Yankees next. The Boston Red Sox are batting .253 on the season, have a .324 OBP, and a .429 slugging percentage. The Boston Red Sox pitching staff has a 3.76 ERA and a 1.30 WHIP. Jarren Duran leads the Boston Red Sox with 125 hits and 65 RBI, while Trevor Story and Ceddanne Rafaela have combined for 216 hits and 124 RBI. The Red Sox will face off against the Miami Marlins this weekend.

Dustin May gets the ball for the Boston Red Sox, and he is 6-8 with a 4.93 ERA and 101 strikeouts this season. This will be May’s second career game against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 67-52 on the year and play the Orioles, Tigers, and Orioles next. The Houston Astros are batting .259 on the season, have a .323 OBP, and a .410 slugging percentage. The Houston Astros pitching staff has a 3.71 ERA and a 1.19 WHIP. Jose Altuve leads the Houston Astros with 127 hits and 63 RBI while Jeremy Pena and Christian Walker have combined for 214 hits and 109 RBI. Over the weekend the Astros will face off against the Baltimore Orioles.

Spencer Arrighetti gets the ball for the Houston Astros, and he is 1-2 with a 7.43 ERA and 13 strikeouts this season. This will be Arrighetti’s second career game against the Boston Red Sox.

Why the Houston Astros will win

• The Astros have won 10 of their last 11 games at Daikin Park against teams that held a winning record.
• The Red Sox have lost seven of their last eight night games against AL West opponents following a road loss.
• The Red Sox have failed to cover the run line in each of their last four road games against AL West opponents.
• The Astros have covered the run line in each of their last three games at Daikin Park.
• The Red Sox have trailed after 3 innings in nine of their last 11 night games against AL West opponents.
• The Red Sox have trailed after 5 innings in nine of their last 11 night games against AL West opponents.

Why the Boston Red Sox will win

• The Astros have lost 12 of their last 13 games as favorites against American League opponents.
• The underdogs have won each of the Astros’ last four games.
• The Astros have failed to cover the run line in each of their last 12 games as home favorites against American League opponents.
• The underdogs have covered the run line in each of the Red Sox’s last five games at Daikin Park.
• The Red Sox have won the first inning in three of their last four night games against American League opponents.
• The Red Sox have led after 3 innings in three of their last four night games against American League opponents.
• The Red Sox have led after 5 innings in three of their last four games as underdogs against American League opponents.

Houston Astros Player Prop Facts

• Yainer Diaz has hit a home run in each of his last two home appearances after playing the previous day.
• Ramon Urias has recorded at least one Double in three of his last four appearances in night games against AL East teams that held a winning record.
• Jake Meyers has recorded at least one hit in each of his last 10 appearances against AL opponents.

Boston Red Sox Player Prop Facts

• Alex Bregman has hit a home run in four of his last five road appearances against AL opponents.
• Dustin May has recorded five or more strikeouts in four of his last five road appearances against AL opponents.
• Alex Bregman has recorded two hits in each of his last five appearances in night games against AL West teams that held a winning record.
• Ceddanne Rafaela has recorded at least one Double in each of the Red Sox’s last three games at Daikin Park against AL West opponents that held a winning record.

Boston Red Sox vs Houston Astros Prediction

We have two capable offenses and two struggling pitchers. May has allowed 25 hits and 16 runs in his last 25 innings, and wasn’t great in his Red Sox debut. Arrighetti has an ERA over seven and a 1.58 WHIP, and he’s pitched just 3.2 innings since April. It’s going to take time for Arrighetti to really get rolling. Given the form of both arms and what the lineups are capable of, I expect some fireworks. Give me the over on Tuesday between the Red Sox and Astros.