Mar 26, 2026; Cincinnati, Ohio, USA; Boston Red Sox left fielder Roman Anthony (19) scores on a RBI single hit by designated hitter Jarren Duran (not pictured) in the ninth inning against the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images
Katie Stratman-Imagn Images

Boston Red Sox vs Cincinnati Reds Prediction 3/28/2026 Today’s MLB Picks

Pick details

MATCHUP Boston Red Sox Cincinnati Reds
Team Records 1-0 0-1
Spread -1.5 113 +1.5 -136
Moneyline -143 +119
Total Over 7.5 (-114) Under 7.5 (-106)
Where Great American Ball Park, Cincinnati, Ohio
When Saturday, March 28, 2026
Time 04:10 PM EDT
TV MLB.TV

The Boston Red Sox and Cincinnati Reds meet Saturday in MLB action at Great American Ball Park. Here’s a Boston Red Sox vs. Cincinnati Reds Prediction. This article will include a Boston Red Sox vs. Cincinnati Reds Pick.

Boston Red Sox Betting Preview


The Boston Red Sox are 1-0 on the year and play the Astros and Padres next. The Boston Red Sox are batting .333 on the season, have a .385 OBP, and have a .361 slugging percentage. The Boston Red Sox pitching staff has a 0.00 ERA and a 0.78 WHIP. Roman Anthony leads the Boston Red Sox with 3 hits and 0 RBI, while Marcelo Mayer and Jarren Duran have combined for 4 hits and 1 RBI.

Sonny Gray gets the ball for the Boston Red Sox, and he was 14-8 with a 4.28 ERA and 201 strikeouts last season. Gray is 1-3 with a 4.18 ERA and 33 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview


The Cincinnati Reds are 0-1 on the year and play the Pirates and Rangers next. The Cincinnati Reds are batting .125 on the season and have a .200 OBP, and a .188 slugging percentage. The Cincinnati Reds pitching staff has a 3.00 ERA and a 1.67 WHIP. Sal Stewart leads the Cincinnati Reds with 3 hits and 0 RBI while Elly De La Cruz and Spencer Steer have combined for 1 hit and 0 RBI.

Brady Singer gets the ball for the Cincinnati Reds, and he was 14-12 with a 4.03 ERA and 163 strikeouts last season. Singer is 2-2 with a 4.88 ERA and 22 strikeouts in his career against the Boston Red Sox.

Why the Cincinnati Reds will win

  • The Reds have won each of their last nine day games at Great American Ball Park following a home loss.
  • The Red Sox have lost each of their last four games as road favorites against NL Central opponents following a road win.
  • The Reds have covered the run line in nine of their last 10 games as home underdogs following a home loss.
  • The Red Sox have failed to cover the run line in seven of their last eight games as favorites against NL Central opponents following a road win.
  • The Red Sox have trailed after 3 innings in four of their last five games as road favorites against NL Central opponents.
  • The Red Sox have trailed after 5 innings in four of their last five games against opponents that held a losing record.

Why the Boston Red Sox will win

  • The Reds have lost each of their last eight home games against AL East opponents following a home loss.
  • The Red Sox have won four of their last five road games against National League opponents that held a losing record.
  • The Reds have failed to cover the run line in each of their last seven games against American League opponents.
  • The favorites have covered the run line in each of the Reds’ last four games.
  • The Reds have trailed after 5 innings in four of their last five games as home underdogs against AL East opponents.

Total Runs Facts

  • Nine of the Red Sox’s last 10 games have gone UNDER the total runs line.
  • Four of the Reds’ last five home games have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last six games at Great American Ball Park.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Red Sox’s last six games as favorites against NL Central opponents.

Cincinnati Reds Player Prop Facts

  • Spencer Steer has recorded at least one hit in each of his last 10 Saturday-day appearances at Great American Ball Park.
  • Brady Singer has recorded five or more strikeouts in each of his last six appearances against opponents that held a winning record.
  • Brady Singer has recorded a win in five of his last six appearances at Great American Ball Park.
  • Will Benson has hit a home run in two of the Reds’ last three games against AL opponents.
  • Elly De La Cruz ranked 7th in the league in Steals (37) last season.

Boston Red Sox Player Prop Facts

  • Trevor Story has recorded a Double in four of his last five appearances with the Red Sox as favorites against the Reds.
  • Sonny Gray has recorded seven or more strikeouts in six of his last seven appearances against NL opponents.
  • Wilyer Abreu has recorded at least one hit in each of his last 12 appearances with the Red Sox as favorites against NL Central opponents.
  • Triston Casas has hit a home run in each of his last three appearances against NL Central opponents that held a losing record.

Matchup/League Facts

  • The Reds ranked 22nd in the league for strikeouts last season (1415).
  • The Reds ranked 21st in the league for home runs last season (167).
  • The Red Sox ranked 4th in the league for batting average last season (.254).
  • The Red Sox were one of only four teams in the league to have ranked top 10 in both steals and batting average last season.

Boston Red Sox vs Cincinnati Reds Prediction


It’s one game, but it usually takes the bats time to get going and find a rhythm. The Reds possibly had the worst offensive showing of any team on opening day. No runs, just four hits and 1-7 with runners in scoring position. Gray still has all-star caliber stuff and he’s coming back to Cincinnati, which should make him excited. The Red Sox have a lineup that’s cooking out of the gate. We’re getting a fairly cheap price. I like the Red Sox to get off to a quick 2-0 start.

Randy Chambers's Pick: Boston Red Sox