Boston Red Sox vs Baltimore Orioles Prediction 8/26/2025 Today’s MLB Picks

The Boston Red Sox and the Baltimore Orioles meet Tuesday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Baltimore Orioles prediction.

Starting Pitching Matchup

The Boston Red Sox will send out Lucas Giolito for the start here and Giolito is 8-2 with a 3.72 ERA and 91 strikeouts this season. In his last five starts against Baltimore, Giolito is 3-1 with a 2.27 ERA and 31 strikeouts. Kyle Bradish will make his season debut for Baltimore here after going 2-0 with a 2.75 ERA and 53 strikeouts last season. In his last five starts against Boston, Bradish is 1-2 with a 7.78 ERA and 21 strikeouts.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to add on to their game looking to add on to their 4-3 win over the Orioles on Monday to sit at 72-60 this season. After this series, the Red Sox will head home for a series against the Pittsburgh Pirates.

Red Sox Win 4 Of Their Last 5 Games

Alex Bregman has 96 hits including 24 doubles along with 16 home runs and 53 RBIs this season. Trevor Story’s added 127 hits with 20 home runs, 82 RBIs and 22 stolen bases while Jarren Duran has 131 hits with 34 doubles, 12 triples, 12 home runs, 70 RBIs and a team-high 21 stolen bases. Kristian Campbell’s added 51 hits with 10 doubles, 6 homers and 21 RBIs while Wilyer Abreu has 22 home runs with 69 RBIs and 6 stolen bases and Ceddanne Rafaela has 14 homers, 26 doubles, 3 triples, 53 RBIs and 19 stolen bases this season.

Why the Boston Red Sox will win

• The road team has won seven of the Orioles’ last eight games.
• The Orioles have lost eight of their last nine night games against American League opponents following a loss.
• The road team has covered the run line in nine of the Orioles’ last 10 games.
• The Orioles have failed to cover the run line in four of their last five games against teams that held a winning record.

Boston Red Sox Player Prop Facts

• Jarren Duran has recorded a Double in four of the Red Sox’s last five road games against opponents that held a losing record.
• Jarren Duran has hit a home run in each of the Red Sox’s last three road games against opponents that held a losing record.
• Lucas Giolito has recorded a win in five of his last six appearances against AL opponents.
• Lucas Giolito has recorded six or more strikeouts in eight of his last nine appearances against AL East opponents that held a losing record.
• Masataka Yoshida has recorded at least one hit in each of his last nine appearances against the Orioles after playing the previous day.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to rebound from their loss at the hands of the Red Sox last time out to sit at 60-71 this season. After this series, the Orioles will take to the road for an interleague series against the San Francisco Giants.

Orioles Drop 4 Of Their Last 5

Adley Rutschman has 70 hits with 16 doubles, 9 homers and 29 RBIs. Jackson Holliday has 118 hits with 17 doubles, 2 triples, 15 homers and 49 RBIs. Gunnar Henderson has 128 hits with 29 doubles, 5 triples, 15 home runs and 57 RBIs with 16 stolen bases and 112 strikeouts while Holliday has a team-high 116 strikeouts as well this season. Heston Kjerstad’s added 4 homers and 19 RBIs while Jordan Westburg has 15 home runs and 34 RBIs this season.

Why the Baltimore Orioles will win

• The underdogs have won five of the last six games between the Red Sox and Orioles.
• The Red Sox have lost four of their last five games as favorites against the Orioles following a win.
• The underdogs have covered the run line in 16 of the Orioles’ last 17 games.
• The Red Sox have failed to cover the run line each of their last six night games against AL East opponents that held a losing record.

Baltimore Orioles Player Prop Facts

• Colton Cowser has hit a home run in each of the Orioles’ last three night games against opponents that held a winning record.
• Gunnar Henderson has recorded a Double in five of the Orioles’ last six games as home underdogs against AL opponents.
• Kyle Bradish has recorded five or more strikeouts in each of his last 10 appearances against AL opponents that held a winning record.
• Ryan Noda has recorded at least one hit in each of his last seven appearances with his team as an underdog against the Red Sox.

Total Runs Facts

• Five of the Orioles’ last six games as home underdogs have gone UNDER the total runs line.
• Nine of the Red Sox’s last 11 games as favorites against American League opponents have gone OVER the total runs line.

Boston Red Sox vs. Baltimore Orioles Prediction

I’m leaning towards the Red Sox here. Giolito hasn’t been my favorite pitcher to back in the past, but there’s really no denying what he’s brought to the table for Boston so far this season and who knows what we’re going to see in Kyle Bradish’s return to the fold for the Orioles in his first start back. The Red Sox are not a great team to see on the other side right away with how hot their bats have been and I think Boston snags another win here. Give me the Red Sox.