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Boston Red Sox vs Arizona Diamondbacks Prediction 9/7/2025 Today’s MLB Picks
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Boston (78-65) vs Arizona (72-71)
September 7, 2025 at 04:10 PM EDT
The Line: Betting Odds: Arizona -106 — Over/Under: +9
In this article, we will formulate a Red Sox vs Diamondbacks Prediction for this MLB game on Sunday, September 7th at the Chase Field in the third game of this series, with the Dbacks having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.
Arizona Diamondbacks Preview
The Arizona Diamondbacks have a 72-71 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 38-33 home record and are 67-67 in over/under They are coming off a 5-1 home victory over the Red Sox, and are 8-2 in their last 10 games. Under is 6-3-1 in their last 10 games and are playing the Twins and the Giants next.
The Diamondbacks have a .250 batting average this season, .323 OBP and .437 slugging percentage. Arizona’s pitching staff has a 4.43 ERA and 1.32 WHIP. Geraldo Perdomo leads the Diamondbacks with 150 hits, adding a team-high 91 RBI. He is also the team’s best hitter with a .286 batting average. Corbin Carroll leads the team in home runs with 29.
Ryne Nelson (R) is the projected starting pitcher for the Diamondbacks, and he has a 7-3 record, 3.57 ERA and 1.05 WHIP.
Boston Red Sox Preview
The Boston Red Sox have a 78-65 record this season and are sitting on the third place of the AL East. The Red Sox have a 34-37 road record and are 70-70 in over/under. They are coming off a 1-5 road defeat by the Dbacks, and have three consecutive losses. They are 5-2 to the over in their last 7 games and are playing the Athletics and the Yankees next.
The Red Sox have a .254 batting average this season, .324 OBP and .425 slugging percentage. Boston’s pitching staff has a 3.78 ERA and 1.30 WHIP. Jarren Duran leads the Red Sox with 142 hits, and he is the team’s best hitter, with a .260 batting average. Trevor Story leads the team in RBI, with 88, adding a team-high 23 home runs.
Brayan Bello (R) is the projected starting pitcher for the Red Sox, and he has a 11-6 record, 3.07 ERA and 1.23 WHIP.
Boston Red Sox @ Arizona Diamondbacks Betting Trends: September 7, 2025
- Probable Starting Pitcher: Ryne Nelson     Record this season: 7-3     ERA: 3.57
- Home Record: 5-1
- Last 5 against Red Sox: 1-0
Why the Arizona Diamondbacks will win
- The Diamondbacks have won seven of their last eight games as underdogs.
- The Red Sox have lost five of their last six games as favorites against National League opponents.
- The Diamondbacks have covered the run line in each of their last nine games as underdogs.
- The Red Sox have failed to cover the run line in seven of their last eight games against the Diamondbacks following a loss.
- The Diamondbacks have led after 5 innings in each of their last seven home games against AL East opponents.
- The Diamondbacks have won the first inning in six of their last seven day games at Chase Field.
- The Diamondbacks have led after 3 innings in seven of their last eight home games.
- Probable Starting Pitcher: Brayan Bello     Record this season: 11-6     ERA: 3.07
- Road Record: 3-3
- Last 5 against Diamondbacks: 0-1
Why the Boston Red Sox will win
- The Red Sox have won each of their last nine Sunday games as road favorites.
- The Red Sox have covered the run line in each of their last nine Sunday games as road favorites.
- The Red Sox have led after 5 innings in five of their last six day games against opponents that held a winning record.
Total Runs Facts
- Each of the Red Sox’s last five road games after playing the previous day have gone UNDER the total runs line.
- Six of the Diamondbacks’ last seven games against AL East opponents have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Diamondbacks’ last seven day games at Chase Field.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Red Sox’s last five day games against NL West opponents.
Arizona Diamondbacks Player Prop Facts
- Corbin Carroll has hit a home run in three of the Diamondbacks’ last five games as underdogs.
- Ryne Nelson has recorded five or more strikeouts in five of his last six home appearances.
- Corbin Carroll has recorded at least one hit in each of his last 11 appearances against AL East opponents.
- Ryne Nelson has recorded a win in three of his last four appearances in day games.
- Corbin Carroll ranks 5th amongst qualified players for Slugging Percentage (.560) this season.
Boston Red Sox Player Prop Facts
- Trevor Story has hit a home run in each of his last two appearances at Chase Field against opponents that held a winning record.
- Trevor Story has recorded at least one hit in each of his last nine appearances at Chase Field against opponents that held a winning record.
- Connor Wong has recorded at least one Double in three of his four previous appearances against the Diamondbacks.
Matchup/League Facts
- The Diamondbacks rank 2nd in the league for triples this season (34).
- The Diamondbacks rank 2nd in the league for RBIs this season (689).
- The Red Sox rank 1st in the league for doubles this season (287).
- The Red Sox rank 5th in the league for hits this season (1246).
Red Sox vs Diamondbacks Prediction
The Dbacks have won their last six head-to-head meetings against the Red Sox, and both teams are tied 3-3 wins in their last 6 meetings in Arizona.
In this Red Sox vs Diamondbacks Prediction, both teams are coming at a pickem price. Both pitchers have been excellent this season, with a combined 6.64 ERA, and their home/away splits are even better, as Nelson has a 2.60 home ERA and Bello a 2.85 road ERA. Both teams are struggling offensively lately, with the Red Sox having just 7 total runs scored in their last 3 games, and the Dbacks having 5 runs or less in five of their last six games. The total is set at 9, and I don’t think there will be 10 runs scored in this game, so take the under in this one.