Sep 11, 2025; Toronto, Ontario, CAN; Toronto Blue Jays starting pitcher Kevin Gausman (34) reacts after a complete game win over the Houston Astros at Rogers Centre. Mandatory Credit: John E. Sokolowski-Imagn Images

Blue Jays vs Rays Prediction 9/17/2025 Today’s MLB Picks

Pick details

Toronto (89-62) vs Tampa Bay (73-78)

September 17, 2025 at 07:05 PM EDT

The Line: Betting Odds: Tampa Bay +110 — Over/Under: +8.5

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In this article we will formulate a Blue Jays vs Rays prediction for this MLB game on Wednesday, September 17th at George M. Steinbrenner Field in Tampa, Florida. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 89-62 this year after they won the first two games in this series by scores of 2-1 and 6-5. In their game two win, Toronto scored four runs in the first two innings and led 6-3, but barely escaped with the victory. The Blue Jays recorded 11 hits and they committed one error in the game, while they were led by Springer, who went 3-5 with two RBIs in the win. Toronto started Berrios, who allowed four hits and three earned runs over 4.0 innings, while Lauer picked up the win and Hoffman got the save. 

Prior to this series, the Blue Jays won all three against the Orioles and two out of three against the Astros. Toronto has won six games in a row and they are currently first in the AL East standings. The Toronto pitching staff has a 4.13 ERA with a 1.26 WHIP and a .238 opponent batting average, while their offense has scored 757 runs with a .269 batting average and a .337 on base percentage this season. Vladimir Guerrero Jr. has led Toronto with 23 home runs and 81 RBIs, while George Springer has added 29 home runs and 78 RBIs this year. The projected starting pitcher for Toronto is Kevin Gausman, who is 10-10 with a 3.44 ERA and a 1.00 WHIP over 177.2 innings pitched this year. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 73-78 this season after they lost game two by a score of 6-5 on Tuesday night. Tampa Bay cut the deficit to 4-3 in the third and 6-5 in the ninth, but couldn’t find the tying run in the loss. The Rays recorded 10 hits in the game and they were led by Lowe, who went 2-5 with one home run and four RBIs in the loss. TB started Pepiot, who allowed four hits and four earned runs over 1.2 innings for the loss, while Gerber and Kelly both allowed one earned run in relief. 

Prior to this series, the Rays lost two out of three against the Cubs and two out of three against the White Sox. Tampa Bay has lost six of their last seven games and they are fourth in the AL East standings. The Tampa Bay pitching staff has a 3.88 ERA with a 1.21 WHIP and a .236 opponent batting average, while the offense has scored 673 runs with a .251 batting average and a .313 on base percentage this season. Junior Caminero has led Tampa Bay with 44 home runs and 108 RBIs, while Brandon Lowe has added 29 home runs and 79 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Ian Seymour, who is 3-2 with a 3.16 ERA and a 1.13 WHIP over 42.2 innings pitched this season. 

Why the Blue Jays will beat the Rays

The Rays have lost each of their last seven games against AL East opponents that held a winning record.
The Blue Jays have won each of their last six games against teams that held a losing record.
The Rays have failed to cover the run line in each of their last eight home games against American League opponents following a home loss.
The Blue Jays have covered the run line in each of their last six Wednesday night games against AL East opponents.

Total Runs Facts

Four of the Blue Jays’ last five road games have gone UNDER the total runs line.
Four of the Rays’ last five games against AL East opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Rays’ last 11 games against AL East opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Blue Jays’ last four games at George M. Steinbrenner Field.

Tampa Bay Rays Player Prop Facts

Brandon Lowe has hit a home run in four of the Rays’ last six home games against the Blue Jays.
Yandy Diaz has recorded at least one hit in each of his last eight appearances after playing the previous day.
Taylor Walls has recorded a Double in each of his last three appearances against AL East opponents.

Toronto Blue Jays Player Prop Facts

George Springer has hit at least one home run in two of the Blue Jays’ last three games as road favorites.
Kevin Gausman has recorded six or more strikeouts in 10 of his last 11 appearances with his team as a favorite against the Rays.
Kevin Gausman has recorded a win in three of his last four appearances with the Blue Jays as favorites against AL East opponents.
Bo Bichette has recorded at least one hit in each of his last 12 appearances against AL opponents.
Ernie Clement has recorded a Double in four of his last five road appearances against AL East opponents.

Blue Jays vs Rays Prediction 

Toronto continues to stack wins and they are trying to extend their winning streak to seven games here. The Blue Jays are 39-37 on the road this year, while the Rays are 38-38 at home. Tampa Bay has lost six of their last seven and they are starting Seymour, who has allowed two earned runs or fewer in four straight outings. Toronto is going with Gausman, who has given up a total of two earned runs in his last 24.0 innings. Take the Blue Jays once again here.

David Racey's Pick: Blue Jays ML

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