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Baltimore Orioles vs Oakland Athletics Prediction 6/6/25 MLB Picks
Pick details
Oakland Athletics (24-40) vs Baltimore Orioles (25-36)
June 6, 2025 at 10:05 PM EDT
The Line: Betting Odds: Oakland Athletics +105 / Baltimore Orioles -125 — Over/Under: 11
The Baltimore Orioles are visiting the Athletics on Friday, June 6th at the Sutter Health Park in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs Athletics Prediction. We will examine:
The Athletics’ recent form and player performance
The Baltimore Orioles’ recent form and player performance
Recent betting trends and streaks involving the Athletics
Recent betting trends and streaks involving the Baltimore Orioles
Recent betting trends in games played between the Baltimore Orioles vs Athletics
A summary that ties it all together and produces a favorable betting outcome for the Baltimore Orioles vs Athletics game
Athletics Preview
The Athletics have a 24-40 record this season and are sitting in last place in the AL West. The Athletics have a 10-22 home record and are 36-23 in over/under. They are coming off a 14-3 home victory over the Twins, which ended their previous nine-game losing streak. Over is 8-1-1 in their last 10 games and are playing the Royals and the Angels next.
The Athletics have a .256 batting average this season, a .323 OBP, and a .421 Slugging percentage. Athletics’ pitching staff has a 5.79 ERA and 1.54 WHIP. Jacob Wilson leads the Athletics with 86 hits and a team-high .363 batting average, while Tyler Soderstrom leads the team with 42 RBI and a team-high 14 home runs.
JP Sears (L) will take the mound for the Athletics, and he has a 4-5 record, 5.05 ERA, and 1.28 WHIP. He has been weaker at home, with a 5.68 ERA across four home starts, and he has been terrible lately, having lost his last four starts and having given up 4+ runs in three of those four starts. JP Sears has a record of 2-3 with an ERA of 6.26 and 27 strikeouts in 6 appearances against the Orioles in his career.
Baltimore Orioles Preview
The Baltimore Orioles have a 23-36 record this season and are sitting in last place in the AL East. The Orioles have a 13-19 road record and 28-29 in over/under. They are coming off a 4-3 road victory over the Mariners and have six consecutive wins. Under is 5-0-1 in their last 6 games, and they are playing the Tigers and the Tigers next.
The Orioles have a .237 batting average this season, a .302 OBP, and a .386 slugging percentage. Baltimore’s pitching staff has a 5.10 ERA and 1.43 WHIP. Ryan O’Hearn leads the Orioles with 59 hits, and he is the team’s best hitter with a .326 batting average. Cedric Mullins leads the team in RBI, with 31, and in home runs, with 10.
Dean Kremer (R) will take the mound for the Orioles, and he has a 5-5 record, 4.70 ERA, and 1.39 WHIP. He has been weaker on the road, with a 6.07 ERA across 8 road starts, but he has been in good form lately, with just one earned run in 11.1 innings pitched in his last two starts. Dean Kremer with an ERA of 5.23 and 7 strikeouts in 2 appearances against the Oakland Athletics in his career.
Why the Athletics will win
- The Orioles have lost five of their last six games as favorites following a road win.
- The Athletics have won nine of their last 10 Friday games against teams that held a losing record.
- The Orioles have failed to cover the run line in each of their last six games as favorites following a road win.
- The underdogs have covered the run line in each of the Orioles’ last four games.
- The Orioles have trailed after 5 innings in six of their last seven night games against American League opponents that held a losing record.
- The Orioles have trailed after 3 innings in nine of their last 11 night games against opponents that held a losing record.
Why the Baltimore Orioles will win
- The Athletics have lost each of their last 15 night games after playing the previous day.
- The Orioles have won each of their last eight games against American League opponents.
- The Athletics have failed to cover the run line each of their last 11 home games against teams that held a losing record.
- The Orioles have covered the run line in six of their last seven games against AL West opponents that held a losing record.
- The Athletics have trailed after 5 innings in nine of their last 10 night games against American League opponents.
- The Athletics have trailed after 3 innings in each of their last four night games against AL East opponents.
Total Runs Facts
- Each of the Athletics’ last nine games against AL East opponents have gone OVER the total runs line.
- Each of the Orioles’ last six night games against American League opponents have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Athletics’ last eight Friday games against American League opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Orioles’ last 10 road games.
Matchup/League Facts
- The Athletics rank 30th in the league for ERA this season (5.79).
- The Athletics rank 30th in the league for home runs allowed this season (97).
- The Orioles rank 29th in the league for home runs allowed this season (90).
- The Orioles rank 28th in the league for ERA this season (5.10).
Baltimore Orioles vs Athletics Prediction
The Orioles are 7-3 in their last 10 overall meetings against the Athletics, and are 5-1 in their last 6 meetings in Oakland. Over is 7-3 in their last 10 meetings.
In this Baltimore Orioles vs Athletics Prediction, the Orioles are coming as -120 road favorites. Both teams have almost identical overall records, but the Athletics are the second-worst home team in the whole MLB, and prior to yesterday’s win, they were in a major slump. I don’t trust either of those pitchers, who have a combined 9.75 ERA, and both teams have bottom-5 bullpens, with a combined 11.37 ERA. Sutter Health Park is a hitter-friendly park, and the total is high for a reason. I expect fireworks offensively tonight, so take the over 11 in this one.