Baltimore Orioles vs Boston Red Sox Prediction 5/25/25 MLB Picks

The Baltimore Orioles and Boston Red Sox meet Sunday in MLB action at Fenway Park. Here’s a Baltimore Orioles vs Boston Red Sox Prediction. This article will include a Baltimore Orioles vs Boston Red Sox Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 17-34 on the year and play the Cardinals, White Sox, and Mariners next. The Baltimore Orioles are batting .235 on the season, have a .303 OBP, and a .385 slugging percentage. The Baltimore Orioles pitching staff has a 5.61 ERA and a 1.49 WHIP. Gunnar Henderson leads the Baltimore Orioles with 47 hits and 14 RBI, while Ryan O’Hearn and Jackson Holliday have combined for 90 hits and 39 RBI. 

Dean Kremer gets the ball for the Baltimore Orioles, and he is 3-5 with a 5.50 ERA and 40 strikeouts this season. Kremer is 2-4 with a 5.64 ERA and 40 strikeouts in his career against the Boston Red Sox.

Boston Red Sox Betting Preview

The Boston Red Sox are 27-26 on the year and play the Brewers, Braves, and Angels next. The Boston Red Sox are batting .254 on the season, have a .326 OBP, and a .427 slugging percentage. The Boston Red Sox pitching staff has a 4.02 ERA and a 1.35 WHIP. Jarren Duran leads the Boston Red Sox with 61 hits and 33 RBI, while Rafael Devers and Alex Bregman have combined for 119 hits and 83 RBI.

Walker Buehler gets the ball for the Boston Red Sox, and he is 4-1 with a 4.00 ERA and 33 strikeouts this season. Buehler is 1-0 with a 1.54 ERA and 15 strikeouts in his career against the Baltimore Orioles.

Why the Boston Red Sox will win

• The Orioles have lost each of their last eight day games following a win.
• The Red Sox have won each of their last five day games against the Orioles following a home loss.
• The Orioles have failed to cover the run line in each of their last six games as underdogs against AL East opponents following a win.
• The Red Sox have covered the run line in each of their last four games as favorites against the Orioles following a loss.
• The Red Sox have led after 3 innings in eight of their last nine Sunday day games as home favorites.

Why the Baltimore Orioles will win

• The underdogs have won five of the Red Sox’s last six games at Fenway Park.
• The Red Sox have lost three of their last four games as favorites against AL East opponents.
• The Red Sox have failed to cover the run line in five of their last six games as home favorites against AL East opponents.
• The underdogs have covered the run line in five of the Red Sox’s last six games at Fenway Park.
• The Red Sox have trailed after 5 innings in each of their last three home day games.

Boston Red Sox Player Prop Facts

• Walker Buehler has recorded a win in each of his three previous appearances in day games against AL teams that held a losing record.
• Rafael Devers has recorded at least one RBI in each of the Red Sox’s last five day games.
• Walker Buehler has recorded seven or more strikeouts in four of his last five home appearances against opponents that held a losing record.
• Jarren Duran has recorded a Single in each of the Red Sox’s last four day games.
• Jarren Duran has scored at least one run in seven of his eight previous appearances in day games against AL East teams that held a losing record.
• Abraham Toro has hit a home run in three of his last four appearances with the Red Sox against AL opponents.
• Connor Wong has recorded a Double in three of his last four appearances in day games against teams that held a losing record.
• Abraham Toro has recorded at least one hit in each of his last nine home appearances against AL East opponents that held a losing record.

Baltimore Orioles vs Boston Red Sox Prediction

The Orioles are a team I’ll continue to fade, and despite them splitting the doubleheader yesterday, they haven’t won two straight games since April 30-May 2. I want nothing to do with the Orioles, and it doesn’t help with Kremer on the mound, a pitcher with a 5.50 ERA and 1.38 WHIP. In 37.2 road innings, Kremer has a 6.93 ERA and a .308 allowed batting average. Buehler has been hit or miss, but he’s allowed seven hits and three runs in his last 8.1 innings. We know what Buehler is capable of when he’s right, a two-time all-star and two-time World Series winner. I’ll gladly take the soft price with the Red Sox at home.