Mar 24, 2025; Mesa, Arizona, USA; Atlanta Braves catcher Drake Baldwin (75) hits an RBI single against the Chicago Cubs in the second inning at Sloan Park. Mandatory Credit: Rick Scuteri-Imagn Images

Atlanta Braves vs Chicago Cubs Prediction 9/1/2025 Today’s MLB Picks

Pick details

Atlanta (62-75) vs Chicago (78-59)

September 1, 2025 at 04:05 PM EDT

The Line: Betting Odds: Chicago -113 — Over/Under: +8

(Get latest betting odds)

In this article, we will formulate a Braves vs Cubs Prediction for this MLB game on Monday, September 1st at the Wrigley Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 78-59 record this season and are sitting on the second place of the NL Central. The Cubs have a 41-25 home record and are 62-64 in over/under. They are coming off a 5-6 road defeat the Rockies, that ended their two-game winning streak. They are playing the Braves and the Nationals next.

The Cubs have a .250 batting average this season, .320 OBP and .429 Slugging percentage. Chicago’s pitching staff has a 3.86 ERA and 1.21 WHIP. Nico Hoerner leads the Cubs with 143 hits, and he is the team’s best hitter with a .289 batting average. Seiya Suzuki leads the team in RBI, with 89, adding a team-high 28 home runs.

Colin Rea (R) is the projected starting pitcher for the Cubs, and he has a 10-6 record, 4.23 ERA and 1.32 WHIP.

Atlanta Braves Preview

The Atlanta Braves have a 62-75 record this season and are sitting on the 4th place of the NL East. The Braves have a 29-42 road record and 62-65 in over/under. They are coming off a 3-1 road victory over the Phillies, that ended their three-game losing streak. Under is 4-1 in their last 5 games and are playing the Cubs and the Mariners next.

The Braves have a .244 batting average this season, .320 OBP and .394 Slugging percentage. Atlanta’s pitching staff has a 4.38 ERA and 1.31 WHIP. Matt Olson leads the Braves with 142 hits, and he is also the team’s best hitter with a .269 batting average. He also leads the team in RBI, with 77, while Marcell Ozuna leads the team in home runs with 21.

Spencer Strider (R) is the projected starting pitcher for the Braves, and he has a 5-12 record, 4.95 ERA and 1.38 WHIP.

Why the Chicago Cubs will win

The Braves have lost seven of their last eight games against NL Central opponents following a win.
The Cubs have won seven of their last eight home games following a road loss.
The Cubs have covered the run line in each of their last seven games against NL East opponents following a road loss.
The Braves have failed to cover the run line in each of their last six Monday games as underdogs against National League opponents.
The Braves have trailed after 3 innings in eight of their last 10 games against National League opponents that held a winning record.
The Braves have trailed after 5 innings in seven of their last eight games against opponents that held a winning record.

Why the Atlanta Braves will win

The Braves have won four of their last five games as underdogs against the Cubs.
The Cubs have lost four of their last five games as home favorites against the Braves following a loss.
The Braves have covered the run line in each of their last six day games against National League opponents.
The Cubs have failed to cover the run line in each of their last four day games against NL East opponents.
The Braves have led after 5 innings in four of their last five games against the Cubs.

Total Runs Facts

Six of the last seven games between the Braves and Cubs have gone UNDER the total runs line.
Five of the Braves’ last six day games against National League opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last six home games against NL East opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Braves’ last 10 games as underdogs.

Matchup/League Facts

The Cubs rank 1st in the league for walks allowed this season (355).
The Cubs rank T3rd in the league for steals this season (135).
The Braves rank 3rd in the league for walks this season (492).
The Braves rank 25th in the league for steals this season (68).

Braves vs Cubs Prediction

The Braves are 7-2 in their last 9 head-to-head meetings against the Cubs, and have won their last two visits in Chicago. Under is 6-1 in their last 7 meetings.

In this Braves vs Cubs Prediction, the Cubs are coming as -125 home favorites. I don’t trust either pitcher in this matchup, as they have a combined 9.18 ERA, and Strider has been weaker on the road, and coming into this matchup in terrible form, with a 1-4 record and 8.75 ERA across his last 5 starts. Chicago has the 4th-best offense in the league, and both teams are better against righties, averaging 9.8 runs per game against right-handed pitching. With the total set at just 7.5 runs, I have to go over that number.

Nikos Lagouretos's Pick: Over 8

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