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Athletics vs St. Louis Cardinals Prediction 9/1/2025 Today’s MLB Picks
Pick details
Oakland (63-75) vs St. Louis (68-70)
September 1, 2025 at 02:15 PM EDT
The Line: Betting Odds: St. Louis -1.5 — Over/Under: +8
The Athletics and St. Louis Cardinals meet Monday in MLB action at Busch Stadium. Here’s a Athletics vs St. Louis Cardinals Prediction. This article will include a Athletics vs St. Louis Cardinals Pick.
Athletics Betting Preview
The Athletics are 63-75 on the year and play the Angels, Red Sox, and Reds next. The Athletics are batting .253 on the season, have a .318 OBP, and a .431 slugging percentage. The Athletics pitching staff has a 4.83 ERA and a 1.37 WHIP. Brent Rooker leads the Athletics with 145 hits and 79 RBI, while Tyler Soderstrom and Tyler Wilson have combined for 259 hits and 133 RBI.
Luis Morales gets the ball for the Athletics, and he is 2-0 with a 1.19 ERA and 22 strikeouts this season. This will be Morales’ first career game against the St. Louis Cardinals.
St. Louis Cardinals Betting Preview
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The St. Louis Cardinals are 68-70 on the year and play the Giants, Mariners, and Brewers next. The St. Louis Cardinals are batting .247 on the season, have a .316 OBP, and a .384 slugging percentage. The St. Louis Cardinals pitching staff has a 4.27 ERA and a 1.31 WHIP. Alec Burleson leads the St. Louis Cardinals with 123 hits and 60 RBI while Masyn Winn and Brendan Donovan have combined for 238 hits and 95 RBI.
Sonny Gray gets the ball for the St. Louis Cardinals, and he is 12-7 with a 4.19 ERA and 168 strikeouts this season. Gray is 2-1 with a 3.38 ERA and 27 strikeouts in his career against the Athletics.
Athletics vs St. Louis Cardinals Prediction
Morales has been incredible in 22.2 innings, allowing 12 hits and three runs, so I gave the A’s a strong look in this one. With that said, it’s still a small sample size, and only 8.2 of those innings came on the road. The Athletics also just looked lifeless in a sweep against the Rangers. Gray is far more trustworthy over what he’s done throughout his career, and he’s allowed 12 earned runs in his last 31 innings. Gray also spent his first four and a half seasons in Oakland, so he should be excited about this matchup, facing a familiar franchise. I’ll roll with the Cards on Monday afternoon.
