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Arizona Diamondbacks vs Washington Nationals Prediction 4/5/25 MLB Picks

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Washington Nationals (1-6) vs Arizona Diamondbacks (5-3)

Game Info: Saturday, April 5, 2025 at 4:05 pm (Nationals Park)

The Line: Betting Odds: Washington Nationals +114 / Arizona Diamondbacks -135 — Over/Under: 9

(Get latest betting odds)


In this article, we will formulate an Arizona Diamondbacks vs Washington Nationals Prediction for this MLB game on Saturday, April 5th, at Nationals Park. To formulate this prediction, we will look at: 

-The Diamondbacks’ recent form and recent player performance 

-The Nationals’ recent form and recent player performance

-Recent Betting trends and streaks involving Arizona

-Recent Betting trends and streaks involving Washington

-Recent betting trends in games played between Arizona and Washington

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Diamondbacks and Nationals. 

Diamondbacks Bounced Back

Two games ago, the Diamondbacks struggled with the pitching against the New York Yankees, but they bounced back Friday. The Diamondbacks gave up four runs, but it didn’t matter because the offense scored six runs on the way to the victory. Corbin Carroll was the star of the show, hitting two home runs and driving in three RBIs. Brandon Pfaadt didn’t have his best stuff on the mound, but he still did enough to secure the win. 

The Diamondbacks are averaging 6.38 runs, while their defense is giving up 5.25 runs per game. The offense has been good, but the pitching has left a whole lot to be desired. As a team, they are batting .271, which is 5th in the league. Eugenio Surarez is having a huge season, and he has hit five home runs. Eduardo Rodriguez is going to get the start, and he sits with a 0-0 record but a higher ERA of 5.06. Against the Chicago Cubs in his first start, he gave up only three hits and three runs. 

Slow Start for the Nationals

It has been quite a slow start for the Nationals, and they are still looking for their first win of the season. CJ Abrams hit a home run on Friday, but it wasn’t enough. They actually had three different players that hit a home run, but that was about the offense they could generate. The Nationals are averaging 3.57 runs, while their defense is pitching and giving up 5.57 runs per game. The offense is ranked 20th, and that isn’t good enough to be competitive. 

Mitchell Parker will start for Washington. He has a 1-0 record and an ERA of 0.00. Against the Philadelphia Phillies, he pitched 6.1 innings, giving up seven hits and zero runs. He played with fire but still came away with a win. 

Arizona Diamondbacks vs Washington Nationals Prediction

Sure, Parker didn’t give up any runs in his first start, but it wasn’t a very comfortable game, and he still gave up seven hits. In this game, the Diamondbacks’ offense is going to put on a show here, and that will be the difference. The Diamondbacks are going to finish with at least seven hits, and this time, it will result in four or five runs for Arizona. The Nationals are going to have no answer here, and Arizona is going to end up cruising. Back the Diamondbacks on the run line.

Shane Mickle's Pick: Arizona Diamondbacks -1.5

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