Arizona Diamondbacks vs San Francisco Giants Prediction 9/8/2025 Today’s MLB Picks

The Arizona Diamondbacks and San Francisco Giants meet on Monday in MLB action from Oracle Park. Here’s an Arizona Diamondbacks vs San Francisco Giants prediction. We will look at this from a betting perspective and determine the best Diamondbacks vs Giants pick. We will examine:

The Arizona Diamondbacks’ recent form and player performance

The San Francisco Giants’ recent form and player performance

Recent betting trends and streaks involving the Giants

Recent betting trends and streaks involving the Diamondbacks

Recent betting trends in games played between Arizona and San Francisco

A summary that ties it all together and produces a favorable betting outcome for the Diamondbacks and Giants game.

Diamondbacks Continue to Struggle

There was a real thought that the Diamondbacks were a playoff team this season, but all season they have been nothing but a major disappointment. The Diamondbacks on Sunday scored only four runs against the Boston Red Sox, while the pitching gave up seven. The starting pitching was fine, but Taylor Rashi was a problem out of the bullpen, going 1.2 innings giving up two hits and three runs. 

The Diamondbacks are averaging 4.94 runs while their pitching is giving up 4.76 runs per game. The offense is ranked 5th while the pitching is ranked 23rd. Nabil Crismatt is going to get the start for the Diamondbacks and he sits with a 2-0 record and an ERA of 2.14. Against the Texas Rangers in his last start he went 6.1 innings giving up seven hits and two runs. 

Why the Diamondbacks Will Beat the Giants

• The Giants have lost each of their last seven games as home favorites against National League opponents following a loss.
• The Diamondbacks have won six of their last seven games as underdogs after playing the previous day.
• The Giants have failed to cover the run line in each of their last 11 games as home favorites against National League opponents following a loss.
• The Diamondbacks have covered the run line in each of their last eight games as underdogs after playing the previous day.
• The Giants have trailed after 5 innings in three of their last four night games against NL West opponents.

What Happened to the Giants?

The questions have had their issues heading into this game and the last few months have been mostly struggles. The Giants over the weekend faced off against the St. Louis Cardinals and they lost two of the last three games. They were competitive in each of the games they lost, but they ended up losing by a run on Saturday and Sunday. On Sunday, the Giants scored three runs in the sixth inning, but managed zero runs the rest of the game and which led to the defeat. 

The Giants are averaging 4.32 runs while their pitching is giving up 4.14 runs per game. The offense is ranked 17th while the pitching is ranked 10th. In this game, they need to find a way to get the offense going. If the offense gets going, this can be a strong end to the season. That is a big if for this team though. Getting the start for the Giants will be Logan Webb who sits with a 13-9 record and an ERA of 3.17. Against the Colorado Rockies, he went five innings giving up seven hits and two runs. 

Why the Giants Will Beat the Diamondbacks

• The Giants have won six of their last seven games at Oracle Park.
• The Diamondbacks have lost four of their last five road games following a loss.
• The Giants have covered the run line in seven of their last eight night games against the Diamondbacks at Oracle Park following a loss.
• The Diamondbacks have failed to cover the run line in five of their last six games at Oracle Park against NL West opponents that held a winning record.

Arizona Diamondbacks vs San Francisco Giants Prediction

Want a good old-fashioned pitchers’ duel? Make sure to tune into this game, because that’s exactly what this game is going to be. Logan Webb sits with an ERA of 3.17, and the Diamondbacks offense is going to have one of those off days. For the Diamondbacks, they send Crismatt who has been quite impressive in himself, and we know the Giants’ offense has been inconsistent all season. Neither team is reaching four runs here. Back the under to cash.