Arizona Diamondbacks vs Milwaukee Brewers Prediction 8/25/2025 Today’s MLB Picks

The Arizona Diamondbacks and the Milwaukee Brewers meet Monday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Diamondbacks vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Eduardo Rodriguez for the start here and Rodriguez is 5-7 with a 5.40 ERA and 115 strikeouts this season. In his career, Rodriguez is 0-2 with a 2.60 ERA and 15 strikeouts against Milwaukee. Brandon Woodruff will start for Milwaukee here and is 4-1 with a 2.47 ERA and 55 strikeouts this season. In his last five starts against the Diamondbacks, Woodruff is 1-1 with a 4.73 ERA and 32 strikeouts.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to rebound from a 6-1 loss at the hands of the Cincinnati Reds in Sunday’s series finale to sit at 64-67 this season. After this series, the Diamondbacks will head on the road for a series against the Los Angeles Dodgers.

Diamondbacks Have Four-Game Win Streak Snapped

Corbin Carroll has 113 hits with 27 home runs, 65 RBIs, 16 triples and 22 doubles this season. Carroll also has 17 stolen bases and Geraldo Perdomo has a team-high 22 stolen bases as well as 13 home runs and 81 RBIs with a team-high 134 hits this season. Ketel Marte’s added 23 home runs and 56 RBIs as well on the year and Lourdes Gurriel has 115 hits with 23 doubles, 17 home runs and 71 RBIs.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last six games as underdogs against NL Central opponents following a home loss.
• The Brewers have lost four of their last five games as favorites.
• The underdogs have covered the run line in each of the Diamondbacks’ last nine games.
• The Brewers have failed to cover the run line in each of their last six games as favorites.

Arizona Diamondbacks Player Prop Facts

• Geraldo Perdomo has hit a home run in three of the Diamondbacks’ last four games as underdogs.
• Eduardo Rodriguez has recorded five or more strikeouts in seven of his eight previous appearances against NL Central opponents that held a winning record.
• Geraldo Perdomo has recorded at least one hit in each of the Diamondbacks’ last 11 games against NL opponents that held a winning record.
• Eduardo Rodriguez has recorded a win in three of his last four road appearances against NL Central opponents.
• Corbin Carroll ranks 5th amongst qualified players for Slugging Percentage (.554) this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to rebound from their 4-3 loss at the hands of the San Francisco Giants last time out to sit at 81-50 this season. After this series, the Brewers will head on the road for a marquee series with the Toronto Blue Jays.

Brewers Drop 5 Of Their Last 7

Brice Turang has 134 hits with 14 home runs, 64 RBIs and 22 stolen bases while Jackson Chourio has 123 hits with a team-high 29 doubles, 18 stolen bases, 17 home runs and 67 RBIs and Sal Frelick has 127 hits as well as 3 triples, 9 home runs, 50 RBIs and 18 stolen bases so far this season. Christian Yelich also has 15 stolen bases with 26 homers and 88 RBIs while also adding 15 doubles. Yelich also has a team-high 143 strikeouts up to this point in the year. William Contreras has 14 homers and 63 RBIs as well this season. Joey Ortiz has chipped in 93 hits with 17 doubles, 7 home runs and 43 RBIs and Caleb Durbin also has 20 doubles with 8 homers and 44 RBIs.

Why the Milwaukee Brewers will win

• The Diamondbacks have lost eight of their last nine road games against NL Central opponents.
• The Brewers have won seven of their last eight night games against teams that held a losing record.
• The Diamondbacks have failed to cover the run line in each of their last six road games against NL Central opponents.
• The Brewers have covered the run line in each of their last six Monday games.

Milwaukee Brewers Player Prop Facts

• Brandon Woodruff has recorded seven or more strikeouts in each of his last seven home appearances against NL West opponents.
• Sal Frelick has recorded at least one hit in each of his last 14 appearances against opponents that held a losing record.
• Brandon Woodruff has recorded a win in each of his last four appearances in night games against teams that held a losing record.
• Jackson Chourio has hit a home run in three of his last four appearances in night games against NL West teams that held a losing record.
• Sal Frelick ranks 8th amongst qualified players for Batting Average (.298) this season.

Total Runs Facts

• Seven of the Diamondbacks’ last eight road games against National League opponents have gone UNDER the total runs line.
• Fifteen of the Brewers’ last 20 games as favorites against NL West opponents have gone UNDER the total runs line.

Arizona Diamondbacks vs. Milwaukee Brewers Prediction

I’m on the Brewers in this one. I just don’t love Eduardo Rodriguez and I don’t love this matchup for him. The Brewers haven’t been as hot over the last week, but they’ve still been smoking left-handed pitching in the month of August and pretty much over the duration of this winning run they’ve had over the last couple of months, and I just think it’s a bad spot for E-Rod to be in. Give me the Brew Crew here.