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Arizona Diamondbacks vs Cincinnati Reds Prediction 6/7/25 MLB Picks

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Cincinnati Reds (30-33) vs Arizona Diamondbacks (31-31)

June 7, 2025 at 04:10 PM EDT

The Line: Betting Odds: Cincinnati Reds -102 / Arizona Diamondbacks -119 — Over/Under: 9.5

(Get latest betting odds)

In this article, we will formulate a Diamondbacks vs Reds prediction for this MLB game on Saturday, June 7, at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks (31-31, 16-14 Away) lost four consecutive series to the Dodgers, Cardinals, Pirates, and Nationals, but bounced back in style, with a sweep of the Atlanta Braves on the road. In the opening game of the series against the Reds, the rain didn’t allow the teams to finish the tilt, so they had to postpone it after six innings with a 3-3 result. Eduardo Rodriguez pitched for 5.0 innings, allowing two runs on six hits with three strikeouts and no walks. 

This year, the Diamondbacks average 5.11 runs per game (4th in the MLB) on a .255/.333/.448 triple-slash. When it comes to pitching, the Diamondbacks’ staff has a 4.76 ERA (24th) and 1.32 WHIP (21st). Eugenio Suarez leads the Diamondbacks with a .230 batting average, 16 home runs, and 46 RBI this season.

The projected starting pitcher for the Diamondbacks is Ryne Nelson, who is 2-1 in three starts this season, with a 3.43 ERA and 1.00 WHIP in 42.0 innings.

Cincinnati Reds Betting Preview

The Cincinnati Reds (30-33, 15-16 Away) defeated the Kansas City Royals, but then lost back-to-back series to the Chicago Cubs and Milwaukee Brewers. Before the rain stopped Game 1 of the series against Arizona, the Reds’ starter Nick Lodolo pitched for 6.0 innings, allowing three runs on five hits with four strikeouts and no walks. 

This season, the Reds average 4.44 runs per game (10th in the MLB) on a .243/.318/.391 triple-slash. When it comes to pitching, the Reds’ staff has a 3.80 ERA (12th) and 1.20 WHIP (11th). Elly De La Cruz leads the Reds with a .257 batting average, 12 home runs, and 43 RBI this season.

Nick Martinez will take the mound for the Reds on Saturday. The 34-year-old right-hander has a 3-6 record in 12 starts this year with a 3.89 ERA and 1.17 WHIP in 69.1 innings.

Total Runs Facts

  • Each of the Diamondbacks’ last four road games on the first leg of a doubleheader have gone OVER the total runs line.
  • Four of the Reds’ last five home games on the first leg of a doubleheader have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the last seven games between the Diamondbacks and Reds.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Diamondbacks’ last five road games against NL Central opponents.

Matchup/League Facts

  • The Reds rank T7th in the league for steals this season (57).
  • The Reds rank 8th in the league for opponent batting average this season (.231).
  • The Diamondbacks rank 4th in the league for home runs this season (87).
  • The Diamondbacks rank T4th in the league for triples this season (12).

Diamondbacks vs Reds Prediction

The Diamondbacks won eight of the previous ten H2H encounters, including six of the last six. Five of the last seven H2H duels went Under, and I am backing another Under in this one because of solid starters. Ryne Nelson, who opened the season as a reliever rather than a starter, experienced an excellent May, during which he allowed only five runs in 25.0 innings. Nick Martinez, on the other hand, struggled in his previous start against the Cubs, but he did register six consecutive quality starts before that. I don’t think the starters will allow more than five runs combined in the opening five or six innings. Go with Under. 

Oliver Zivic's Pick: Under 9.5

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