Angels vs Guardians Prediction 5/13/2026 Today’s MLB Picks

In this article we will formulate an Angels vs Guardians prediction for this MLB game on Wednesday, May 13th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Angels Betting Preview

The Los Angeles Angels are 16-27 this year after they lost the first two games in this series by scores of 2-7 and 2-3. In game two, Los Angeles cut the deficit to 2-1 in the sixth and 3-2 in the eighth, but couldn’t find the tying run. The Angels recorded eight hits and they committed one error in the game, while they were led by Grissom, who went 1-4 with one home run and one RBI. Urena allowed three hits and two earned runs over 5.0 innings for the loss, while Fermin pitched a scoreless inning in relief. Prior to this series, Los Angeles lost two out of three against the Blue Jays, but did win two out of three against the White Sox before that. 

This season, Los Angeles has a 4.58 ERA with a 1.44 WHIP and a .241 opponent batting average, while they have scored 181 runs with a .233 batting average and a .321 on base percentage. Jorge Soler has led the Angels with eight home runs and 28 RBIs, while Mike Trout has added 11 home runs and 23 RBIs. The projected starting pitcher for Los Angeles is Reid Detmers, who is 1-3 with a 4.33 ERA and a 1.24 WHIP over 43.2 innings pitched this year. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 23-21 this season after they won game two by a score of 3-2 last night. Cleveland led 2-0 after the fifth inning and they were able to hang on for the win. The Guardians recorded four hits in the game and they were led by Martinez, who went 2-3 with one home run and one RBI. Cecconi allowed five hits and zero earned runs over 4.0 innings, while Gaddis picked up the win and Smith got the save. Prior to this series, Cleveland lost two out of three against the Twins and split four games with the Royals. 

This season, Cleveland has a 3.85 ERA with a 1.28 WHIP and a .238 opponent batting average, while they have scored 183 runs with a .228 batting average and a .322 on base percentage. Chase DeLauter has led the Guardians with six home runs and 25 RBIs, while Jose Ramirez has added six home runs and 16 RBIs. The projected starting pitcher for Cleveland is Parker Messick, who is 4-1 with a 2.30 ERA and a 0.98 WHIP over 47.0 innings pitched this season. 

Why the Cleveland Guardians will win

• The Angels have lost each of their last 11 games at Progressive Field following a road loss.
• The Guardians have won each of their last 10 day games against the Angels following a home win.
• The Angels have failed to cover the run line each of their last five day games against AL Central opponents that held a winning record.
• The Guardians have covered the run line in five of their last six day games against the Angels at Progressive Field following a win.
• The Guardians have led after 5 innings in each of their last three games against the Angels.
• The Guardians have led after 3 innings in each of their last three games against the Angels at Progressive Field.

Why the Los Angeles Angels will win

• The Guardians have lost six of their last eight games as home favorites against American League opponents following a home win.
• The Angels have won three of their last four Wednesday games as underdogs against American League opponents.
• The Guardians have failed to cover the run line in nine of their last 10 games as home favorites against American League opponents following a home win.
• The Angels have covered the run line in eight of their last nine games against teams that held a winning record.

Total Runs Facts

• Seven of the Angels’ last nine day games against American League opponents have gone OVER the total runs line.
• Three of the Guardians’ last four day games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Angels’ last six day games at Progressive Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last five games between the Angels and Guardians.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit at least one home run in six of the Guardians’ last 12 games as favorites against the Angels.
• Steven Kwan has recorded a hit in each of the Guardians’ last eight Wednesday day games.

Los Angeles Angels Player Prop Facts

• Mike Trout has hit at least one home run in four of the Angels’ last five road games against opponents that held a winning record.
• Mike Trout has recorded at least one hit in each of the Angels’ last eight games as underdogs against the Guardians.
• Mike Trout ranks T10th in the league in Home Runs (11) this season.

Matchup/League Facts

• The Guardians rank 3rd in the league for steals this season (44).
• The Guardians rank 3rd in the league for walks this season (188).
• The Angels rank 26th in the league for runs allowed this season (211).
• The Angels rank 25th in the league for ERA this season (4.58).

Angels vs Guardians Prediction 

Cleveland comes into this matchup looking to complete the sweep and they have allowed two runs in three of their last four games. The Guardians are 12-9 at home this year, while the Angels are 8-17 on the road. Los Angeles continues to struggle over the last two weeks and they have scored two runs or fewer in four of their last five. The Angels are starting Detmers, who has allowed 3+ earned runs in three of his last four starts, while Messick has allowed one earned run in two of his last three outings. Take the Guardians to get another win here.

David Racey's Pick: Guardians ML