Aug 26, 2025; Arlington, Texas, USA; Los Angeles Angels starting pitcher Yusei Kikuchi (16) throws during the first inning against the Texas Rangers at Globe Life Field. Mandatory Credit: Kevin Jairaj-Imagn Images

Angels vs Astros Prediction 9/1/2025 Today’s MLB Picks

Pick details

Los Angeles (64-72) vs Houston (75-62)

September 1, 2025 at 02:10 PM EDT

The Line: Betting Odds: Houston -139 — Over/Under: +8.5

(Get latest betting odds)

In this article we will formulate an Angels vs Astros prediction for this MLB game on Monday, September 1st at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Angels Betting Preview

The Los Angeles Angels are 64-72 this year after they won two of the first three games in this series by scores of 0-2, 4-1, and 3-0. In their game three win, Los Angeles scored once in the fifth and twice in the eighth, which was enough to secure the shutout victory. The Angels recorded six hits in the game and they were led by Trout and Peraza, who both had one RBI in the win. Los Angeles started Soriano, who allowed one hit and zero earned runs over 7.0 innings for the win, while Jansen got the save. 

Prior to this series, the Angels lost two out of three against the Rangers and all three against the Cubs. Los Angeles has lost three of their last five games and they are currently fourth in the AL West standings. The Los Angeles pitching staff has a 4.72 ERA with a 1.43 WHIP and a .261 opponent batting average, while the offense has scored 581 runs with a .229 batting average and a .303 on base percentage this season. Taylor Ward has led LA with 30 home runs and 94 RBIs, while Jo Adell has added 30 home runs and 82 RBIs this year. The projected starting pitcher for Los Angeles is Yusei Kikuchi, who is 6-9 with a 3.68 ERA and a 1.43 WHIP over 154.0 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 75-62 this season after they lost game three by a score of 3-0 on Sunday afternoon. Houston got a pretty solid performance from their pitchers, but never got the offense going in the loss. The Astros recorded just two hits and they committed one error in the game, while they were led by Alvarez and Urias, who both had one hit in the loss. Houston started Brown, who allowed three hits and one earned run over 6.0 innings for the loss, while McCullers Jr. allowed two earned runs in relief. 

Prior to this series, the Astros won two out of three against the Rockies and three out of four against the Orioles. Houston has won three of their last five games and they are currently first in the AL West standings. The Houston pitching staff has a 3.83 ERA with a 1.22 WHIP and a .232 opponent batting average, while their offense has scored 572 runs with a .252 batting average and a .318 on base percentage this season. Jose Altuve has led Houston with 23 home runs and 65 RBIs, while Christian Walker has added 21 home runs and 74 RBIs this year. The projected starting pitcher for Houston is Luis Garcia, who is making his first appearance of the season due to injury. 

Why the Astros will beat the Angels 

The Astros have won 17 of their last 19 games against the Angels at Daikin Park following a loss.
The Angels have lost eight of their last nine games following a road win.
The Astros have covered the run line in seven of their last eight day games against the Angels at Daikin Park following a loss.
The Angels have failed to cover the run line in each of their last six Monday day road games against American League opponents.

Why the Angels will beat the Astros 

The Astros have lost seven of their last eight games as home favorites against AL West opponents.
The Angels have won each of their last eight Monday games against American League opponents.
The Astros have failed to cover the run line in 16 of their last 17 games at Daikin Park against American League opponents that held a losing record.
The Angels have covered the run line in nine of their last 10 day games against American League opponents.
The Angels have led after 5 innings in each of their last three day games against AL West opponents that held a winning record.

Total Runs Facts

Each of the Astros’ last six home games have gone UNDER the total runs line.
Each of the Angels’ last three games against AL West opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last six games as home favorites against American League opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Angels’ last six day games at Daikin Park.

Houston Astros Player Prop Facts

Isaac Paredes has recorded at least one Double in three of his last four appearances in day games.
Isaac Paredes has hit a home run in each of his last three home appearances against the Angels.
Isaac Paredes has recorded at least one hit in each of his last 10 home appearances against the Angels.

Los Angeles Angels Player Prop Facts

Nolan Schanuel has hit a home run in each of his last two road appearances against the Astros.
Nolan Schanuel has recorded at least one hit in each of his 10 previous road appearances against the Astros.
Yusei Kikuchi has recorded six or more strikeouts in each of his last six appearances at Daikin Park.

Matchup/League Facts

The Astros rank 4th in the league for hits allowed this season (1058).
The Astros rank 26th in the league for triples this season (11).
The Angels rank 29th in the league for hits this season (1037).
The Angels rank 29th in the league for doubles this season (187).

David Racey is 16-7 (70%) overall in the last two days. Click here for his premium plays for this today!

Angels vs Astros Prediction 

Los Angeles has had some very solid pitching so far in this series and they will look to get the series win here. The Angels are 30-37 on the road this year, while the Astros are 41-30 at home. Houston is only leading the AL West by two games right now and they are starting Garcia, who is a welcomed addition, but could show some rust. LA is starting Kikuchi, who has allowed at least four earned runs in three of his last four outings. I don’t love either pitcher coming into this game, so I am going to take the over here.

David Racey's Pick: Over 8.5

Need More? Get Premium Picks

Hot Cappers

Latest Picks & Game Previews

  • Miami Marlins vs Washington Nationals Prediction 9/1/2025 Today’s MLB Picks

    September 01, 2025

  • Guardians vs Red Sox Prediction 9/1/2025 Today’s MLB Picks

    September 01, 2025

  • Lorenzo Musetti vs Jaume Munar Prediction 9/1/2025 Today’s Tennis Picks

    September 01, 2025

  • Angels vs Astros Prediction 9/1/2025 Today’s MLB Picks

    September 01, 2025

  • Jannik Sinner vs Alexander Bublik Prediction 9/1/2025 Today’s Tennis Picks

    September 01, 2025

  • TCU vs North Carolina Prediction 9/1/2025 Today’s College Football Picks

    September 01, 2025

  • Houston Dynamo vs Los Angeles Galaxy Prediction 07/25/2025 Picks

    September 06, 2025