Angels vs Astros Prediction 3/28/2026 Today’s MLB Picks

In this article we will formulate an Angels vs Astros prediction for this MLB game on Saturday, March 28th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Angels Betting Preview

The Los Angeles Angels are 2-0 this season after they won games one and two by scores of 3-0 and 6-2. In the game two win, Los Angeles jumped out to a 5-1 lead in the fifth inning and they added one more in the ninth in the victory. The Angels recorded 11 hits and they committed two errors, while they were led by Lowe, who went 2-4 with one home run and three RBIs in the win. Kikuchi allowed eight hits and two earned runs over 4.1 innings, while Zeferjahn picked up the win in relief. 

Last season, Los Angeles had a 4.89 ERA with a 1.43 WHIP and a .260 opponent batting average, while they scored 673 runs with a .225 batting average and a .298 on base percentage. Taylor Ward (now in Baltimore) led the way with 36 home runs and 103 RBIs, while Jo Adell added 37 home runs and 98 RBIs. The projected starting pitcher for Los Angeles is Reid Detmers, who went 5-3 with a 3.96 ERA and a 1.30 WHIP over 63.2 innings pitched last season. 

Houston Astros Betting Preview

The Houston Astros are 0-2 this year after they lost game two in this series by a score of 6-2 on Friday night. Houston tied the game at one in the first inning, but they only scored one run in the last eight innings in the loss. The Astros recorded eight hits in the game and they were led by Alvarez, who went 1-5 with one home run and one RBI. Burrows allowed nine hits and five earned runs over 5.2 innings for the loss, while Weiss allowed two hits and one earned run in the ninth. 

Last season, Houston had a 3.86 ERA with a 1.22 WHIP and a .232 opponent batting average, while they scored 686 runs with a .250 batting average and a .315 on base percentage. Christian Walker led the team with 27 home runs and 88 RBIs, while Jose Altuve added 26 home runs and 77 RBIs. The projected starting pitcher for Houston is Cristian Javier, who went 2-4 with a 4.62 ERA and a 1.27 WHIP over 37.0 innings pitched last year. 

Why the Houston Astros will win

• The Astros have won 14 of their last 16 games against the Angels following a loss.
• The Angels have lost 11 of their last 13 night games against the Astros following a win.
• The Angels have failed to cover the run line in five of their last six games as road underdogs after playing the previous day.
• The Astros have covered the run line in 12 of their last 15 night games against the Angels at Daikin Park following a loss.

Why the Los Angeles Angels will win

• The underdogs have won four of the Angels’ last five games at Daikin Park.
• The Astros have lost seven of their last eight night games against AL West opponents.
• The Astros have failed to cover the run line in 13 of their last 14 night games against AL West opponents following a home loss.
• The road team has covered the run line in each of the Angels’ last four games.
• The Angels have led after 5 innings in each of their last three games against American League opponents that held a losing record.
• The Angels have led after 3 innings in each of their last three games against American League opponents that held a losing record.

Total Runs Facts

• Eight of the Astros’ last nine games as favorites against the Angels have gone UNDER the total runs line.
• Each of the Angels’ last five games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six games between the Angels and Astros at Daikin Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in three of the Angels’ last four road games against AL West opponents.

Houston Astros Player Prop Facts

• Yordan Alvarez has recorded at least one hit in each of his last 11 Saturday night appearances with the Astros at Daikin Park.
• Jeremy Pena has hit a home run in each of his last two appearances after playing the previous day.
• Cristian Javier has recorded five or more strikeouts in each of his last six Saturday appearances with the Astros as favorites.
• Cristian Javier has recorded a win in three of his last four appearances at Daikin Park against opponents that held a winning record.

Los Angeles Angels Player Prop Facts

• Josh Lowe has recorded a Double in four of his last five road appearances against AL West opponents.
• Nolan Schanuel has recorded at least one hit in each of his 12 previous appearances at Daikin Park.
• Mike Trout has hit at least one home run in five of the Angels’ last six games as underdogs.

Angels vs Astros Prediction 

Houston comes into this matchup looking for their first win of the season, but they have scored just two runs through two games. The Astros are starting Javier, who has battled injuries over the last two years, so we will see what we get from him. LA has to be thrilled with their start to the season and they are starting Detmers, who allowed quite a few base runners in 2025, but did a decent job of limiting runs. I can’t back this Houston offense right now, so give me the Angels to win.

David Racey's Pick: Angels ML