Washington Nationals vs Seattle Mariners Prediction 5/27/25 MLB Picks

The Washington Nationals and the Seattle Mariners meet Tuesday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Washington Nationals vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Washington Nationals will send Mitchell Parker out for the start here, and Parker is 4-3 with a 4.39 ERA and 36 strikeouts this season. This will be Parker’s first career start against the Mariners. The Seattle Mariners did not have a starting pitcher announced at the time that this article was posted.

Washington Nationals Recap

The Washington Nationals come into this game looking to bounce back from a 3-2 loss at the hands of the Giants last time out to drop to 24-29 on the year. After this series, the Nationals will head on the road for a series against the Arizona Diamondbacks.

Nationals Looking For Some Consistency

Keibert Ruiz has 49 hits with 9 doubles and a pair of home runs with 20 RBIs, while James Wood has 57 hits with 13 doubles and a team-high 13 home runs, along with 36 RBIs and 7 stolen bases while also putting up 61 strikeouts. Nathaniel Lowe has 45 hits with 9 doubles and 34 RBIs, along with 8 home runs and 61 strikeouts. CJ Abrams has 8 home runs and 19 RBIs along with 10 doubles and 9 stolen bases, while Luis Garcia Jr. has 9 doubles and 7 stolen bases of his own this season. Dylan Crews has also logged a team-high 11 stolen bases this season.

Why the Washington Nationals will win

• The underdogs have won seven of the Nationals’ last eight games.
• The Mariners have lost four of their last five games as favorites.
• The Nationals have covered the run line in each of their last nine road games against AL West opponents following a loss.
• The Mariners have failed to cover the run line in 11 of their last 12 games as favorites.

Washington Nationals Player Prop Facts

• Nathaniel Lowe has hit a home run in each of his last two appearances against AL West opponents.
• Nathaniel Lowe has recorded at least one RBI in five of his last six appearances against AL West opponents.
• Keibert Ruiz has scored a run in six of the Nationals’ last seven games against the Mariners.
• Keibert Ruiz has recorded at least one Single in each of the Nationals’ last six games against the Mariners.
• Keibert Ruiz has recorded at least one hit in each of his last 10 appearances after not playing the previous day.
• Amed Rosario has recorded a Double in four of his last five appearances against opponents that held a winning record.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to rebound from a 5-3 loss at the hands of the Houston Astros last time out to slip to 29-23 on the year. After this series, the Mariners will take on the Minnesota Twins in a home series.

Mariners Split Last 8 Games

Jorge Polanco has 37 hits, including 10 home runs and 30 RBIs, while Cal Raleigh has 48 hits with 10 doubles, a team-high 17 home runs, and 35 RBIs. Randy Arozarena has 42 hits with 11 doubles, 6 home runs, 21 RBIs, and 9 stolen bases. Julio Rodriguez also has 49 hits with a pair of triples, 9 home runs, 29 RBIs, and 6 stolen bases. Dylan Moore has 8 homers and 8 stolen bases as well this season. Rowdy Tellez has also added 8 home runs and 23 RBIs, while J.P. Crawford has 45 hits with 5 doubles, 4 home runs, and 19 RBIs.

Why the Seattle Mariners will win

• The Mariners have won each of their last eight home games against National League opponents following a road loss.
• The Nationals have lost seven of their last eight games against American League opponents that held a winning record.
• The Mariners have covered the run line in seven of their last eight home games against National League opponents following a road loss.
• The Nationals have failed to cover the run line in six of their last seven games against American League opponents that held a winning record.

Seattle Mariners Player Prop Facts

• Randy Arozarena has scored at least one run in each of his last eight appearances in night games against NL East teams that held a losing record.
• J.P. Crawford has recorded at least one Single in each of the Mariners’ last seven games as favorites against NL opponents.
• Randy Arozarena has recorded at least one hit in each of his last 10 appearances against NL East opponents that held a losing record.
• Jorge Polanco has recorded at least one RBI in each of the Mariners’ last four games against NL East opponents.
• Jorge Polanco has hit at least one home run in each of the Mariners’ last three night games against NL opponents that held a losing record.
• Cal Raleigh ranks 4th in the league in Home Runs (17) this season.

Total Runs Facts

• Each of the Mariners’ last eight games as home favorites have gone OVER the total runs line.
• Twelve of the Nationals’ last 13 night games against American League opponents have gone UNDER the total runs line.

Washington Nationals vs. Seattle Mariners Prediction

I’m leaning towards Seattle here. I get that Washington is a bit of a tempting underdog, but the thing is that Mitchell Parker really struggled in his road outings last year, and I’m not about to think that all of a sudden, that’s changed. The Mariners have cooled off since their strong run earlier this month, but there’s still value in backing them in spots, and I think the Mariners get the job done here. Give me Washington in this one.