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Tampa Bay Rays vs Minnesota Twins Prediction 5/27/25 MLB Picks

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Minnesota Twins (29-24) vs Tampa Bay Rays (27-26)

May 27, 2025 at 07:05 PM EDT

The Line: Betting Odds: Minnesota Twins -122 / Tampa Bay Rays +102 — Over/Under: 8.5

(Get latest betting odds)

The Minnesota Twins are visiting the Tampa Bay Rays on Tuesday, May 27th at the George M. Steinbrenner Field in the second game of this series, with the Rays having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Minnesota Twins vs Tampa Bay Rays Prediction. We will examine:

The Tampa Bay Rays’ recent form and player performance

The Minnesota Twins’ recent form and player performance

Recent betting trends and streaks involving the Tampa Bay Rays

Recent betting trends and streaks involving the Minnesota Twins

Recent betting trends in games played between the Minnesota Twins vs Tampa Bay Rays

A summary that ties it all together and produces a favorable betting outcome for the Minnesota Twins vs Tampa Bay Rays game

Tampa Bay Rays Preview

The Tampa Bay Rays have a 27-26 record this season and are sitting in second place in the AL East. The Rays have a 17-18 home record and are 20-30 in over/under. They are coming off a 7-2 home victory over the Twins and have six consecutive wins. Under is 6-2-1 in their last 9 games and are playing the Astros and the Rangers next.

The Rays have a .245 batting average this season, a .309 OBP, and a .379 slugging percentage. Tampa’s pitching staff has a 3.66 ERA and 1.19 WHIP.  Yandy Diaz leads the Rays with 48 hits and a team-high 29 RBI, while Jonathan Aranda is the team’s best hitter with a .302 batting average.

Taj Bradley (R) will take the mound for the Rays, and he has a 4-3 record, 4.61 ERA, and 1.31 WHIP. He has been better at home with a 3.72 ERA across six home starts, but he has given at least two runs in nine of his ten starts this season. Taj Bradley has a record of 0-1 with an ERA of 5.09 and 20 strikeouts in 3 appearances versus the Twins in his career.

Minnesota Twins Preview

The Minnesota Twins have a 29-24 record this season and are sitting in third place in the AL Central. The Twins have an 11-16 road record and are 18-30 in over/under. They are coming off a 2-7 road defeat by the Rays and have back-to-back losses. Under is 6-2-2 in their last 10 games and are playing the Orioles and the Tigers next.

The Twins have a .238 batting average this season, a .307 OBP, and a .379 Slugging percentage. Minnesota’s pitching staff has a 3.28 ERA and 1.16 WHIP. Ty France leads the Twins with 47 hits and a team-high 29 RBI. Byron Buxton leads the team in home runs, with 10, and he is the team’s best hitter with a .261 batting average.

Joe Ryan (R) will take the mound for the Twins, and he has a 4-2 record, 2.68 ERA, and 0.81 WHIP. He has been slightly better on the road with a 2.48 ERA across five road starts, and he has been in excellent form lately, with just two earned runs in 25 innings pitched across his last four starts. In his previous start versus the Rays last season, he gave up one run in 6 innings of work.  

Why the Tampa Bay Rays will win

  • The Twins have lost each of their last eight night games against AL East opponents that held a winning record.
  • The Rays have won each of their last six games.
  • The Twins have failed to cover the run line each of their last eight night games against AL East opponents that held a winning record.
  • The Rays have covered the run line in each of their last 12 Tuesday games as underdogs against American League opponents.
  • The Twins have trailed after 3 innings in eight of their last nine road games against AL East opponents that held a winning record.
  • The Twins have trailed after 5 innings in seven of their last eight night games against AL East opponents that held a winning record.

Why the Minnesota Twins will win

  • The Twins have won eight of their last nine games against AL East opponents.
  • The Rays have lost eight of their last nine games against AL Central opponents.
  • The Twins have covered the run line in each of their last 10 Tuesday games against American League opponents.
  • The Rays have failed to cover the run line each of their last six Tuesday night games against teams that held a winning record.
  • The Rays have lost the first inning in three of their last four night games against AL Central opponents.
  • The Rays have trailed after 3 innings in each of their last six Tuesday night games against opponents that held a winning record.
  • The Rays have trailed after 5 innings in each of their last six Tuesday games against opponents that held a winning record.

Total Runs Facts

  • Eight of the Twins’ last nine night games after playing the previous day have gone UNDER the total runs line.
  • Six of the Rays’ last seven games as underdogs against AL Central opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last eight Tuesday games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Rays’ last eight night games against American League opponents.

Matchup/League Facts

  • The Rays rank T1st in the league for steals this season (71).
  • The Rays rank 4th in the league for walks allowed this season (151).
  • The Twins rank 1st in the league for walks allowed this season (128).
  • The Twins rank 2nd in the league for runs allowed this season (183).

Minnesota Twins vs Tampa Bay Rays Prediction

The Rays are 5-2 in their last 7 meetings against the Twins, and are 3-1 in their last 4 meetings in Tampa. Under is 5-2-2 in their last 9 meetings.

In this Minnesota Twins vs Tampa Bay Rays Prediction, the Twins are coming as -125 home favorites. The Twins are rightfully favored in this spot, as they have a better overall record, and the Rays are below average at home. The Rays have been red-hot lately, but Joe Ryan has been elite for the Twins this season, and he is coming in excellent form into this matchup. On the other hand, Bradley has been mediocre this season and has been very bad against Twins bats, so I like the Twins here as long as those two pitchers are on the mound. Take the Minnesota Twins on the moneyline in the first 5 innings.

Nikos Lagouretos's Pick: Minnesota Twins F5 ML

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