Minnesota Twins vs Milwaukee Brewers Prediction 5/16/25 MLB Picks

The Minnesota Twins and Milwaukee Brewers meet Friday in MLB action at American Family Field. Here’s a Minnesota Twins vs Milwaukee Brewers Prediction. This article will include a Minnesota Twins vs Milwaukee Brewers Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 24-20 on the year and play the Guardians, Royals, and Rays next. The Minnesota Twins are batting .239 on the season, have a .309 OBP, and a .382 slugging percentage. The Minnesota Twins pitching staff has a 3.30 ERA and a 1.16 WHIP. Byron Buxton leads the Minnesota Twins with 41 hits and 27 RBI, while Ty France and Trevor Larnach have combined for 78 hits and 44 RBI. 

Joe Ryan gets the ball for the Minnesota Twins, and he is 3-2 with a 2.74 ERA and 54 strikeouts this season. Ryan is 0-0 with a 3.97 ERA and 9 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 21-23 on the year and play the Orioles, Pirates, and Red Sox next. The Milwaukee Brewers are batting .233 on the season, have a .310 OBP, and a .355 slugging percentage. The Milwaukee Brewers’ pitching staff has a 4.15 ERA and a 1.32 WHIP. Jackson Chourio leads the Milwaukee Brewers with 48 hits and 25 RBI, while Brice Turang and Sal Frelick have combined for 82 hits and 26 RBI.

Chad Patrick gets the ball for the Milwaukee Brewers, and he is 2-3 with a 3.19 ERA and 36 strikeouts this season. This will be Patrick’s first career game against the Minnesota Twins.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last eight Friday night games as underdogs against AL Central opponents.
• The Twins have lost seven of their last eight games as favorites against NL Central opponents following a road win.
• The Twins have failed to cover the run line in each of their last seven games as favorites against National League opponents following a win.
• The Brewers have covered the run line in each of their last nine Friday night games as underdogs against American League opponents.
• The Twins have trailed after 3 innings in four of their last five road games.
• The Twins have trailed after 5 innings in four of their last five road games against NL Central opponents.

Why the Minnesota Twins will win

• The Twins have won each of their last 10 games following a win.
• The Brewers have lost each of their last three night games against American League opponents.
• The Twins have covered the run line in each of their last seven night games following a win.
• The Brewers have failed to cover the run line in five of their last six night games against teams that held a winning record.
• The Brewers have trailed after 5 innings in four of their last five night games against opponents that held a winning record.

Milwaukee Brewers Player Prop Facts

• Rhys Hoskins has recorded a Double in each of the Brewers’ last three home games against AL opponents.
• Christian Yelich has hit a home run in three of his last four home appearances against AL opponents that held a winning record.
• Jackson Chourio has recorded at least one RBI in each of the Brewers’ last four games against the Twins.
• Rhys Hoskins has scored at least one run in six of his seven previous appearances against the Twins.
• Brice Turang has recorded at least one Single in each of his last six appearances in night games against teams that held a winning record.
• Christian Yelich has recorded at least one hit in each of his last 12 appearances at American Family Field against AL opponents that held a winning record.

Minnesota Twins Player Prop Facts

• Joe Ryan has recorded seven or more strikeouts in four of his last five appearances.
• Harrison Bader has recorded at least one hit in each of his last eight road appearances.
• Christian Vazquez has recorded a Single in each of his last five road appearances.
• Willi Castro has recorded a Double in each of the Twins’ last three road games against NL Central opponents.
• Willi Castro has recorded an RBI in each of the Twins’ last four games as favorites against NL Central opponents.
• Carlos Correa has hit a home run in two of the Twins’ last three night games against NL opponents that held a losing record.
• Byron Buxton has scored at least one run in eight of his last nine appearances against opponents that held a losing record.

Minnesota Twins vs Milwaukee Brewers Prediction

Patrick has been solid this season with a 3.19 ERA and 1.25 WHIP, but it’s not enough for me to get off the Twins. The Twins haven’t lost a game since May 2, and their offense has caught fire during this streak. Ryan is also putting up CY Young consideration numbers as he has a 2.74 ERA and 0.83 WHIP while also being top-20 in strikeouts. Through 46 innings, Ryan is allowing a .196 batting average and is averaging more than a strikeout per frame. I’m just not trying to step in front of a team that’s won every game over the last two weeks and has one of the best pitchers on the hill. It’s a near pick ’em price, folks. Give me the Twins.