Houston Astros vs Milwaukee Brewers Prediction 5/7/25 MLB Picks

Milwaukee Brewers (19-18) vs Houston Astros (17-18)

Game Info: Wednesday, May 7, 2025 at 1:10 pm (American Family Field)

F. Valdez (L) vs Q. Priester (R)

Betting Odds: Milwaukee Brewers +110 / Houston Astros -130 --- Over/Under: 7.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

The Houston Astros and the Milwaukee Brewers meet Wednesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The Houston Astros will send out Framber Valdez for the start here, and Valdez is 1-4 with a 4.39 ERA and 37 strikeouts this season. This will be Valdez’s first career start against the Brewers. The Milwaukee Brewers will start Quinn Priester here, and Priester is 1-0 with a 5.79 ERA and 17 strikeouts this season. This will be Priester’s first career start against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to bounce back from their 4-3 loss at the hands of the Brewers in Tuesday’s matchup to improve to 17-18 on the year. After this series, the Astros will head home for an interleague series against the Cincinnati Reds.

Astros Lose 5 Of Their Last 6 Games

Jose Altuve has 35 hits, including 4 home runs and 14 RBIs. Jeremy Pena also has 36 hits with 4 homers and 12 RBIs with 5 stolen bases, while Yordan Alvarez has 4 doubles and a team-high 18 RBIs with 21 strikeouts as well. Jake Meyers has 5 doubles as well, and Christian Walker has also accrued a team-high 40 strikeouts so far this season. Altuve also has 3 stolen bases, while Jake Meyers has a team-high 7 stolen bases this season. Isaac Paredes also has a team-high 4 home runs with 14 RBIs of his own, and Cam Smith has contributed 3 homers and 10 RBIs.

Why the Houston Astros will win

  • The Astros have won each of their last five day games following a loss.
  • The Brewers have lost four of their last five day games against the Astros following a win.
  • The Astros have covered the run line in seven of their last eight games as favorites following a road loss.
  • The Brewers have failed to cover the run line in each of their last four games as underdogs following a home win.

Houston Astros Player Prop Facts

  • Framber Valdez has recorded six or more strikeouts in each of his last four road appearances against opponents that held a winning record.
  • Jeremy Pena has recorded at least one Single in each of the Astros' last eight games as favorites.
  • Yordan Alvarez has hit at least one home run in 11 of his last 27 appearances with the Astros as road favorites.
  • Yordan Alvarez has recorded an RBI in four of his last five appearances against opponents that held a winning record.
  • Mauricio Dubon has recorded at least one hit in each of his last 11 Wednesday appearances.
  • Victor Caratini has scored at least one run in seven of his last eight appearances in day games.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to add on to their win over the Astros from Tuesday’s matchup to improve their record to 19-18 on the year. After this series, the Brewers will head out on the road for an interleague series against the Tampa Bay Rays.

Brewers Win Third In A Row

Brice Turang has a team-high 41 hits with 3 home runs, 16 RBIs, and 8 stolen bases, while Jackson Chourio has 39 hits with a team-high 12 doubles, 6 home runs, and 24 RBIs, and Sal Frelick has 35 hits as well as 2 triples and 7 stolen bases so far this season. Christian Yelich also has 7 stolen bases with 6 homers and 25 RBIs while also adding 3 doubles. Yelich also has a team-high 38 strikeouts up to this point in the year. William Contreras has 3 homers and 19 RBIs as well this season.

Why the Milwaukee Brewers will win

  • The Brewers have won 10 of their last 11 games as underdogs against AL West opponents.
  • The Astros have lost eight of their last nine games as road favorites against NL Central opponents.
  • The Brewers have covered the run line in 11 of their last 12 games as underdogs against AL West opponents.
  • The Astros have failed to cover the run line in eight of their last nine games as favorites against NL Central opponents.

Milwaukee Brewers Player Prop Facts

  • Jackson Chourio has hit at least one home run in three of the Brewers' last seven day games against opponents that held a losing record.
  • Jackson Chourio has recorded a Double in four of the Brewers' last five home games against AL opponents that held a losing record.
  • Jackson Chourio has recorded at least one RBI in six of the Brewers' last seven home games against AL opponents that held a losing record.
  • Brice Turang has scored at least one run in five of the Brewers' last six home games against opponents that held a losing record.
  • Brice Turang has recorded at least one Single in each of the Brewers' last seven home games against AL opponents that held a losing record.
  • Christian Yelich has recorded at least one hit in each of his last 17 appearances with his team as a home underdog against AL opponents.
  • Brice Turang ranks 8th amongst qualified players for Batting Average (.318) this season.

Total Runs Facts

  • Each of the Astros' last seven games as favorites have gone OVER the total runs line.
  • Seven of the Brewers' last eight games as underdogs against American League opponents have gone OVER the total runs line.

Houston Astros vs. Milwaukee Brewers Prediction

I’m on the Astros in this one. I get the case to be made for the Brew Crew, as Milwaukee’s been the better team so far in this series. However, the Astros have a clear edge in starting pitching in this game, and I think Valdez can put the Astros in a spot to salvage something from this series. Give me the Astros in this one.

Chris’s Pick Houston Astros -130

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

18+ Has gambling become a problem for you? Call the National Problem Gambling Hotline.
1-800-522-4700 | ncpgambling.org

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss