Chicago White Sox vs Kansas City Royals Prediction 5/7/25 MLB Picks

Kansas City Royals Betting Preview

The Kansas City Royals are 21-16 on the year and play the Red Sox, Astros, and Cardinals next. The Kansas City Royals are batting .238 on the season, have a .300 OBP, and a .360 slugging percentage. The Kansas City Royals pitching staff has a 3.04 ERA and a 1.20 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 44 hits and 19 RBI, while Maikel Garcia and Salvador Perez have combined for 70 hits and 32 RBI.

Michael Wacha gets the ball for the Kansas City Royals, and he is 1-4 with a 3.52 ERA and 29 strikeouts this season. Wacha is 5-1 with a 3.21 ERA and 53 strikeouts in his career against the Chicago White Sox.

Why the Kansas City Royals will win

• The White Sox have lost each of their last 12 night games against AL Central opponents that held a winning record.
• The Royals have won 17 of their last 18 home games against AL Central opponents that held a losing record.
• The White Sox have failed to cover the run line in 12 of their last 14 night games against AL Central opponents.
• The favorites have covered the run line in six of the White Sox's last seven games at Kauffman Stadium.
• The Royals have led after 5 innings in eight of their last nine Wednesday night games as home favorites.

Why the Chicago White Sox will win

• The Royals have lost three of their last four Wednesday night games as home favorites against AL Central opponents.
• The White Sox have won three of their last four games against American League opponents following a loss.
• The Royals have failed to cover the run line in each of their last four night games against AL Central opponents following a home win.
• The White Sox have covered the run line in each of their last four games as underdogs against American League opponents following a loss.

Kansas City Royals Player Prop Facts

• Bobby Witt Jr. has recorded a Double in four of the Royals' last five games against AL Central opponents that held a losing record.
• Michael Wacha has recorded five or more strikeouts in nine of his last 10 home appearances against opponents that held a losing record.
• Bobby Witt Jr. has scored at least one run in seven of the Royals' last eight games against the White Sox.
• Kyle Isbel has recorded at least one hit in each of his last seven appearances with the Royals as home favorites.
• Bobby Witt Jr. has recorded at least one Single in each of the Royals' last 10 games as favorites against the White Sox.
• Michael Wacha has recorded a win in seven of his last eight appearances in night games against AL Central teams that held a losing record.
• MJ Melendez has hit a home run in three of his last four appearances against the White Sox at Kauffman Stadium.
• MJ Melendez has recorded at least one RBI in each of his last four home appearances against the White Sox.
• Bobby Witt Jr. ranks T8th in the league in Hits (44) this season.

Chicago White Sox Player Prop Facts

• Josh Rojas has recorded at least one RBI in three of his last four appearances against AL opponents.
• Andrew Benintendi has recorded at least one Single in seven of his last eight appearances against AL Central opponents.
• Andrew Benintendi has hit a home run in three of his last six appearances against former teams.
• Andrew Benintendi has recorded at least one hit in nine of his last 10 appearances against AL Central opponents.
• Andrew Benintendi has scored a run in each of his last five appearances with the White Sox as underdogs.

Chicago White Sox vs Kansas City Royals Prediction

As I’ve said time and time again this season, I want absolutely nothing to do with the White Sox. They’ve been the worst team in baseball over the last three years and continue to burn a hole in bettors' pockets. Cannon isn’t changing much, especially when he has a 6.35 ERA and .244 allowed batting average in 22.2 road innings. The Royals have been on fire over the last couple of weeks, and that shouldn’t stop here against a downright terrible franchise. Wacha has been respectable this season, which includes allowing 11 hits and three runs in his last 12.1 innings. The White Sox do nothing for me, and we’ve been making a killing fading them over the years. Give me the Royals and the RL for max betting value.