San Francisco Giants vs San Diego Padres Prediction 4/30/25 MLB Picks

Giants Looking To Rebound

Jung Hoo Lee leads the Giants with 35 hits, including a team-high 11 doubles, along with a pair of triples, 3 home runs, and 16 RBIs with 3 stolen bases, while Heliot Ramos has 28 hits with 7 doubles, 3 home runs, and 10 RBIs. Wilmer Flores also has a team-high 7 home runs and 28 RBIs, while Mike Yastrzemski has 4 home runs with 13 RBIs and 6 doubles, and Tyler Fitzgerald has a team-high 5 stolen bases as well on the year.

Why the San Francisco Giants will win

• The Giants have won eight of their last nine games as underdogs following a road loss.
• The Padres have lost each of their last three games as favorites.
• The Giants have covered the run line in nine of their last 10 games as road underdogs following a loss.
• The Padres have failed to cover the run line in four of their last five games.

San Francisco Giants Player Prop Facts

• Matt Chapman has hit a home run in each of the Giants' last two day games against NL opponents that held a winning record.
• Heliot Ramos has recorded at least one Double in four of the Giants' last five day games against NL West opponents that held a winning record.
• Heliot Ramos has scored at least one run in each of the Giants' last eight road games against NL opponents.
• Jung Hoo Lee has recorded at least one Single in each of his last nine appearances with the Giants as underdogs against NL opponents.
• Heliot Ramos has recorded at least one hit in each of the Giants' last 14 road games against NL opponents.
• Casey Schmitt has recorded an RBI in each of his last four appearances against NL West opponents.
• Jung Hoo Lee ranks T9th in the league in Hits (36) this season.

San Diego Padres Recap

The San Diego Padres will be out to build on their series-opening win over the Giants to improve their record to 18-11 on the year. After this series, the Padres will head on the road again for a series against the Pittsburgh Pirates.

Padres Snap Four-Game Losing Skid

Manny Machado has 28 hits, including a team-high 10 doubles and 6 stolen bases, while Fernando Tatis Jr. has 36 hits with a team-high 8 home runs and 18 RBIs, along with 7 stolen bases of his own this season. Luis Arraez has added 25 hits with 3 doubles, while Jackson Merrill’s added 14 hits with 3 home runs and 10 RBIs as well. Xander Bogaerts also has 8 doubles and 4 stolen bases this season. Gavin Sheets also has 4 doubles, 3 home runs, and 12 RBIs as well this season.

Why the San Diego Padres will win

• The Padres have won each of their last nine games as home favorites following a win.
• The Giants have lost four of their last five road games.
• The Padres have covered the run line in each of their last 10 home games following a win.
• The Giants have failed to cover the run line in seven of their last eight day games against teams that held a winning record.

San Diego Padres Player Prop Facts

• Jose Iglesias has recorded a Double in three of his last four appearances with his team as a home favorite against the Giants.
• Fernando Tatis Jr. has hit at least one home run in three of the Padres' last four games as favorites against NL opponents.
• Elias Diaz has recorded at least one RBI in each of his last four appearances in day games against NL West teams that held a winning record.
• Luis Arraez has scored at least one run in each of the Padres' last six games as favorites against the Giants.
• Jose Iglesias has recorded at least one Single in each of his last 13 appearances in day games against teams that held a winning record.
• Jose Iglesias has recorded at least one hit in each of his last 13 appearances in day games against teams that held a winning record.
• Fernando Tatis Jr. ranks 7th amongst qualified players for Slugging Percentage (.596) this season.

Total Runs Facts

• Each of the Giants' last nine games as underdogs have gone OVER the total runs line.
• Each of the Padres' last six day games as favorites have gone UNDER the total runs line.

San Francisco Giants vs. San Diego Padres Prediction

I’m on the under in this game. Roupp and King are solid options for their respective rotations, and I think this could end up being a bit of a pseudo Pitcher’s duel. The bullpens on both sides have also been some of the best in baseball over the last couple of weeks and while we saw runs come in bunches in Tuesday’s matchup, one win is not going to convince me all of a sudden that these offenses are back in business and are going to be operating at a high level going forward. I still think this is going to end up being a low-scoring affair, so give me the under in this one.