Mets vs Nationals Prediction 4/25/25 MLB Picks

Washington Nationals (11-14) vs New York Mets (18-7)

Game Info: Friday, April 25, 2025 at 6:45 pm (Nationals Park)

K. Senga (R) vs J. Irvin (R)

Betting Odds: Washington Nationals +142 / New York Mets -170 --- Over/Under: 8.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

In this article we will formulate a Mets vs Nationals prediction for this MLB game on Friday, April 25th at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

New York Mets Betting Preview

The New York Mets are 18-7 this year after they swept the Phillies in three games by scores of 5-4, 5-1, and 4-3. In their game three win, the Mets blew an early 2-0 lead, but they were able to rally in the 10th inning, where they scored twice for the win. New York recorded 10 hits and they committed one error in the game, while they were led by Baty, who went 1-2 with one home run and two RBIs in the win. The Mets started Peterson, who allowed eight hits and two earned runs over 5.1 innings, while Kranick pitched the final two outs in the top of the 10th to get the win. 

Prior to that series, the Mets swept the Cardinals in three games, but did lose two out of three against the Twins before that. New York has won seven games in a row and they are currently first in the NL East standings. The New York pitching staff has a 2.34 ERA with a 1.18 WHIP and a .217 opponent batting average, while the offense has scored 105 runs with a .234 batting average and a .310 on base percentage this season. Pete Alonso has led New York with six home runs and 26 RBIs, while Brandon Nimmo has added four home runs and 10 RBIs this year. The projected starting pitcher for New York is Kodai Senga, who is 3-1 with a 0.79 ERA and a 0.97 WHIP over 22.2 innings pitched this year. 

Washington Nationals Betting Preview

The Washington Nationals are 11-14 this season after they won two out of three against the Orioles by scores of 7-0, 4-3, and 1-2. In their game three loss, the Nationals led 1-0 in the second inning, but couldn’t find anymore offense in the loss. Washington recorded five hits in the game and they were led by Bell, who had their lone RBI in the loss. The Nationals started Gore, who allowed four hits and two earned runs over 6.0 innings in the loss, while Ferrer and Henry pitched three scoreless innings in relief. 

Prior to that series, the Nationals won two out of three against the Rockies, but did lose three out of four against the Pirates before that. Washington has won four of their last six games and they are currently fourth in the NL East standings. The Washington pitching staff has a 4.69 ERA with a 1.40 WHIP and a .253 opponent batting average, while the offense has scored 105 runs with a .232 batting average and a .301 on base percentage this season. James Wood has led Washington with eight home runs and 18 RBIs, while Nathaniel Lowe has added four home runs and 19 RBIs this year. The projected starting pitcher for Washington is Jake Irvin, who is 2-0 with a 3.68 ERA and a 1.06 WHIP over 29.1 innings pitched this season. 

Why the Nationals will beat the Mets 

  • The home team has won each of the last eight games between the Mets and Nationals.
  • The Mets have lost four of their last five games as road favorites following an extra innings win.
  • The underdogs have covered the run line in each of the Nationals' last eight games at Nationals Park.
  • The Mets have failed to cover the run line in each of their last six Friday night games as road favorites against NL East opponents.
  • The Mets have trailed after 5 innings in three of their last four road games against National League opponents.

Why the Mets will beat the Nationals 

  • The Mets have won each of their last seven games.
  • The Nationals have lost eight of their last nine night games against the Mets following a loss.
  • The Mets have covered the run line in seven of their last eight games after going to extra innings.
  • The Nationals have failed to cover the run line in nine of their last 10 games as underdogs against the Mets following a loss.
  • The Nationals have trailed after 5 innings in three of their last four night games against NL East opponents.

Total Runs Facts

  • Each of the Nationals' last six games as underdogs have gone UNDER the total runs line.
  • Four of the Mets' last five road games against NL East opponents have gone OVER the total runs line.
  • The 'Inning 1 OVER 0.5 runs' market has hit in each of the Mets' last seven games as road favorites against National League opponents.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in each of the last six night games between the Mets and Nationals at Nationals Park.

Washington Nationals Player Prop Facts

  • Nathaniel Lowe has hit a home run in each of the Nationals' last two home games against NL East opponents.
  • Nathaniel Lowe has recorded two or more RBIs in each of his last four home appearances against NL East opponents that held a winning record.
  • Luis Garcia has scored at least one run in each of his last 13 Friday night appearances against teams that held a winning record.
  • Keibert Ruiz has recorded at least one Single in eight of his last nine home appearances after playing the previous day.
  • Josh Bell has recorded at least one hit in each of his last 12 appearances against the Mets at Nationals Park.

New York Mets Player Prop Facts

  • Jeff McNeil has hit at least one home run in each of his last three appearances in night games against NL East teams that held a losing record.
  • Tyrone Taylor has recorded a Double in each of the Mets' last three games against the Nationals.
  • Kodai Senga has recorded a win in each of his last three appearances.
  • Brandon Nimmo has recorded at least one RBI in each of his last five appearances against the Nationals after not playing the previous day.
  • Francisco Lindor has recorded at least one Single in 12 of his last 13 appearances with the Mets as road favorites against NL opponents.
  • Kodai Senga has recorded five or more strikeouts in eight of his nine previous appearances with the Mets as favorites against NL East opponents.
  • Francisco Lindor has scored at least one run in nine of his last 10 appearances in night games against NL East teams that held a losing record.
  • Starling Marte has recorded at least one hit in each of his last 11 appearances against the Nationals.

Mets vs Nationals Prediction 

New York comes into this series on a nice winning streak and they have one of the best records in the MLB, but they are just 6-6 on the road. Washington has also had some success in their last two series and they are 7-5 at home. The Nationals are coming off of a tough loss on Thursday night against Baltimore and they will go against Senga, who has allowed a grand total of zero earned runs in his last three starts. On the other side, New York will go up against Irvin, who has allowed two earned runs in his last two starts (13.1 IP). I like both pitchers in this matchup and I lean towards the under here. 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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