San Diego Padres vs Athletics Prediction 4/8/25 MLB Picks

Athletics (4-7) vs San Diego Padres (9-2)

Game Info: Tuesday, April 8, 2025 at 10:05 pm (Sutter Health Park)

D. Cease (R) vs J. Springs (L)

Betting Odds: Athletics +124 / San Diego Padres -148 --- Over/Under: 8.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

The San Diego Padres and Athletics meet on Tuesday in MLB action at Sutter Health Park. Here’s a San Diego Padres vs Athletics Prediction. This article will include a San Diego Padres vs Athletics Pick.

San Diego Padres Betting Preview

The San Diego Padres are 9-2 on the year and play the Rockies, Cubs, and Astros next. The San Diego Padres are batting .282 on the season, have a .351 OBP, and a .422 slugging percentage. The San Diego Padres' pitching staff has a 2.88 ERA and a 1.15 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 16 hits and 7 RBI, while Manny Machado and Jackson Merrill have combined for 28 hits and 14 RBI. 

Dylan Cease gets the ball for the San Diego Padres, and he is 1-0 with a 3.38 ERA and 14 strikeouts this season. Cease is 3-1 with a 4.28 ERA and 40 strikeouts in his career against the Athletics.

Athletics Betting Preview

The Athletics are 4-7 on the year and play the Mets, White Sox, and Brewers next. The Athletics are batting .242 on the season, have a .308 OBP, and a .416 slugging percentage. The Athletics' pitching staff has a 5.60 ERA and a 1.56 WHIP. Tyler Soderstrom leads the Athletics with 16 hits and 10 RBI, while Jacob Wilson and Lawerence Butler have combined for 27 hits and 10 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 1-1 with a 4.00 ERA and 12 strikeouts this season. Springs is 0-1 with a 16.88 ERA and 0 strikeouts in his career against the San Diego Padres.

Why the Athletics will win

  • The Padres have lost five of their last eight games as road favorites against American League opponents.
  • The Athletics have won five of their last six Tuesday games as underdogs.
  • The Padres have failed to cover the run line each of their last eight Tuesday games against AL West opponents that held a losing record.
  • The Athletics have covered the run line in seven of their last eight night games against NL West opponents.

Why the San Diego Padres will win

  • The Padres have won each of their last eight games against American League opponents.
  • The Athletics have lost nine of their last 10 home games after playing the previous day.
  • The Padres have covered the run line in six of their last seven road games against the Athletics.
  • The Athletics have failed to cover the run line in five of their last six home games.
  • The Padres have won the first inning in three of their last four road games against American League opponents that held a losing record.
  • The Padres have led after 3 innings in five of their last six games as favorites.
  • The Athletics have trailed after 5 innings in each of their last 11 Tuesday night games against NL West opponents that held a winning record.

Matchup/League Facts

  • The Athletics rank 3rd in the league for home runs this season (18).
  • The Athletics rank 28th in the league for ERA this season (5.60).
  • The Padres rank 3rd in the league for steals this season (18).
  • The Padres rank T3rd in the league for strikeouts against this season (68).

San Diego Padres vs Athletics Prediction

The Padres have been on fire through 11 games, and they’re just a team I’m excited to step in front of. The Athletics can’t get out of their own way, and they’ve been killed in every game they’ve played at their new home. In four home games this season, the Athletics have been outscored 13-40. With losses in six of their last eight games overall and their performance in Sacramento, it’s hard to get behind the A’s with confidence. Give me the Padres and the reasonable price in game 2 between San Diego and the Athletics. 

Randy’s Pick San Diego Padres -148

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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