Cincinnati Reds vs San Francisco Giants Prediction 4/8/25 MLB Picks

San Francisco Giants (8-2) vs Cincinnati Reds (4-7)

Game Info: Tuesday, April 8, 2025 at 9:45 pm (Oracle Park)

N. Lodolo (L) vs L. Roupp (R)

Betting Odds: San Francisco Giants -130 / Cincinnati Reds +110 --- Over/Under: 7.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

In this article, we will formulate a Reds vs Giants prediction for this MLB game on Tuesday, April 8, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Betting Preview

The Cincinnati Reds (4-7, 2-3 Away) lost all three series early in the season. Although they secured a win in each of the series, the Reds fell to the Giants, Rangers, and Brewers. Cincinnati surprised the Giants 2-0 in the opening game of the current series, thanks to Blake Dunn, who hit a 2-RBI double in the 8th inning. Hunter Greene got a win after allowing no runs on four hits with seven strikeouts and one walk in 8.2 innings.

This year, the Reds average 3.73 runs per game (19th in the MLB) on a .207/.269/.340 triple-slash. When it comes to pitching, the Reds’ staff has a 3.09 ERA (6th) and 0.97 WHIP (2nd). Elly De La Cruz leads the Reds with a .256 batting average, two home runs, and ten RBI this season.

Nick Lodolo will take the mound for the Reds on Tuesday. The 27-year-old southpaw has a 1-1 record in two starts this year with a 1.42 ERA and 0.71 WHIP over 12.2 innings of work.

San Francisco Giants Betting Preview

The San Francisco Giants (8-2, 3-1 Home) were in a fantastic streak of seven wins before the Reds came to Oracle Park and shut them down in a 2-0 win. It was the first time this season that San Francisco failed to score a run. So far, the Giants swept the Mariners and Astros and won two of three games against the Reds in the opening series of the season. In a recent 2-0 loss, Logan Webb was great through 7.0 innings, allowing no runs on four hits with ten strikeouts and no walks.

This season, the Giants average 4.90 runs per game (10th in the MLB) on a .228/.296/.398 slash line. Regarding pitching, the Giants’ staff has a 2.77 ERA (3rd) and 1.20 WHIP (10th). Wilmer Flores leads the Giants with a .250 batting average, four home runs, and 12 RBI this season.

The projected starting pitcher for the Giants is Landen Roupp, who has a 0-0 record in one start this year with a 6.75 ERA and 2.00 WHIP in 4.0 innings.

Why the Reds will beat the Giants

  • The underdogs have won four of the last five games between the Reds and Giants at Oracle Park.
  • The Giants have lost three of their last four games as home favorites against National League opponents.
  • The Reds have covered the run line in nine of their last 10 night games against National League opponents.
  • The Giants have failed to cover the run line in seven of their last eight games as home favorites against National League opponents.

Total Runs Facts

  • Eight of the Reds' last 10 road games have gone UNDER the total runs line.
  • Each of the Giants' last three night games after playing the previous day have gone UNDER the total runs line.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in 12 of the Reds' last 13 games as road underdogs against National League opponents.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in six of the Giants' last seven night games.

Matchup/League Facts

  • The Giants rank T6th in the league for doubles this season (20).
  • The Giants rank 7th in the league for steals this season (13).
  • The Reds rank T3rd in the league for walks allowed this season (27).
  • The Reds rank 3rd in the league for opponent batting average this season (.194).

Reds vs Giants Prediction

The Giants won six of the previous ten H2H encounters, including three of the last five. The teams have already met four times this year, and the series is tied at 2-2. I trust Lodolo more than Roupp as he posted 2-of-2 quality starts and allowed just two earned runs in two starts, while Roupp struggled in his first start this season. I don't think he will improve on Tuesday, which is why I am backing the Reds to prevail.

 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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